STRINGSTRING
PGBD1 PGBD1 ZNF174 ZNF174 ZKSCAN8 ZKSCAN8 ZSCAN20 ZSCAN20 SCAND1 SCAND1 ZKSCAN3 ZKSCAN3 ZKSCAN4 ZKSCAN4 ZSCAN32 ZSCAN32 ZNF213 ZNF213 ZNF396 ZNF396
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGBD1piggyBac transposable element derived 1. (809 aa)
ZNF174Zinc finger protein 174; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family. (407 aa)
ZKSCAN8Zinc finger protein with KRAB and SCAN domains 8; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (578 aa)
ZSCAN20Zinc finger and SCAN domain-containing protein 20; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (1043 aa)
SCAND1SCAN domain-containing protein 1; May regulate transcriptional activity. (179 aa)
ZKSCAN3Zinc finger protein with KRAB and SCAN domains 3; Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas. (538 aa)
ZKSCAN4Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. (545 aa)
ZSCAN32Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (697 aa)
ZNF213Zinc finger protein 213; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (459 aa)
ZNF396Zinc finger protein 396; Isoform 1 and isoform 2 act as DNA-dependent transcriptional repressors. (335 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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