(7 nodes) Mixed, incl. Transposase activity, and Domain of unknown function DUF4371 network (Homo sapiens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ZNF862	Zinc finger protein 862; May be involved in transcriptional regulation. (1169 aa)
	THAP9	DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition. (903 aa)
	HARBI1	Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. (349 aa)
	PGBD2	piggyBac transposable element derived 2. (592 aa)
	NAIF1	Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family. (327 aa)
	PGBD5	PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. (524 aa)
	ZBED8	Protein ZBED8; Zinc finger BED-type containing 8. (594 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HARBI1	NAIF1	ENSP00000317743	ENSP00000362170	Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.	Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family.	0.922
HARBI1	PGBD2	ENSP00000317743	ENSP00000331643	Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.	piggyBac transposable element derived 2.	0.449
HARBI1	PGBD5	ENSP00000317743	ENSP00000375733	Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.	PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene.	0.663
HARBI1	THAP9	ENSP00000317743	ENSP00000305533	Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.	DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition.	0.592
HARBI1	ZBED8	ENSP00000317743	ENSP00000386184	Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.	Protein ZBED8; Zinc finger BED-type containing 8.	0.433
NAIF1	HARBI1	ENSP00000362170	ENSP00000317743	Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family.	Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.	0.922
NAIF1	PGBD2	ENSP00000362170	ENSP00000331643	Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family.	piggyBac transposable element derived 2.	0.456
NAIF1	PGBD5	ENSP00000362170	ENSP00000375733	Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family.	PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene.	0.495
NAIF1	ZBED8	ENSP00000362170	ENSP00000386184	Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family.	Protein ZBED8; Zinc finger BED-type containing 8.	0.460
PGBD2	HARBI1	ENSP00000331643	ENSP00000317743	piggyBac transposable element derived 2.	Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.	0.449
PGBD2	NAIF1	ENSP00000331643	ENSP00000362170	piggyBac transposable element derived 2.	Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family.	0.456
PGBD2	PGBD5	ENSP00000331643	ENSP00000375733	piggyBac transposable element derived 2.	PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene.	0.542
PGBD2	THAP9	ENSP00000331643	ENSP00000305533	piggyBac transposable element derived 2.	DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition.	0.563
PGBD2	ZBED8	ENSP00000331643	ENSP00000386184	piggyBac transposable element derived 2.	Protein ZBED8; Zinc finger BED-type containing 8.	0.692
PGBD2	ZNF862	ENSP00000331643	ENSP00000223210	piggyBac transposable element derived 2.	Zinc finger protein 862; May be involved in transcriptional regulation.	0.603
PGBD5	HARBI1	ENSP00000375733	ENSP00000317743	PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene.	Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.	0.663
PGBD5	NAIF1	ENSP00000375733	ENSP00000362170	PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene.	Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family.	0.495
PGBD5	PGBD2	ENSP00000375733	ENSP00000331643	PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene.	piggyBac transposable element derived 2.	0.542
PGBD5	THAP9	ENSP00000375733	ENSP00000305533	PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene.	DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition.	0.802
PGBD5	ZBED8	ENSP00000375733	ENSP00000386184	PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene.	Protein ZBED8; Zinc finger BED-type containing 8.	0.477