(13 nodes) Mostly uncharacterized, incl. GMP binding, and UPF0606 protein KIAA1549 network (Homo sapiens)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	DEPDC7	DEP domain containing 7; Belongs to the DEPDC7 family. (511 aa)
	KRT12	Keratin, type I cytoskeletal 12; May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity (By similarity). (494 aa)
	PRRG4	Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family. (226 aa)
	IMMP1L	Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO. (166 aa)
	KIAA1549L	UPF0606 protein KIAA1549L; KIAA1549 like; Belongs to the UPF0606 family. (1849 aa)
	CCDC73	Coiled-coil domain containing 73. (1079 aa)
	TCP11L1	T-complex protein 11-like protein 1; T-complex 11 like 1. (509 aa)
	MPPED2	Metallophosphoesterase MPPED2; Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system. (294 aa)
	OR13C5	Olfactory receptor 13C5; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. (318 aa)
	C11orf91	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91. (193 aa)
	QSER1	Glutamine and serine rich 1. (1735 aa)
	DCDC1	Doublecortin domain-containing protein 1; Microtubule-binding protein which plays an important role in mediating dynein-dependent transport of RAB8A-positive vesicles to the midbody during cytokinesis. (890 aa)
	DNAJC24	DnaJ homolog subfamily C member 24; Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta); Belongs to the DPH4 family. (149 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C11orf91	CCDC73	ENSP00000368296	ENSP00000335325	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	Coiled-coil domain containing 73.	0.447
C11orf91	DEPDC7	ENSP00000368296	ENSP00000241051	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	DEP domain containing 7; Belongs to the DEPDC7 family.	0.418
C11orf91	KIAA1549L	ENSP00000368296	ENSP00000315295	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	UPF0606 protein KIAA1549L; KIAA1549 like; Belongs to the UPF0606 family.	0.446
C11orf91	OR13C5	ENSP00000368296	ENSP00000363911	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	Olfactory receptor 13C5; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	0.507
C11orf91	QSER1	ENSP00000368296	ENSP00000382241	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	Glutamine and serine rich 1.	0.414
C11orf91	TCP11L1	ENSP00000368296	ENSP00000335595	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	T-complex protein 11-like protein 1; T-complex 11 like 1.	0.507
CCDC73	C11orf91	ENSP00000335325	ENSP00000368296	Coiled-coil domain containing 73.	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	0.447
CCDC73	DCDC1	ENSP00000335325	ENSP00000385936	Coiled-coil domain containing 73.	Doublecortin domain-containing protein 1; Microtubule-binding protein which plays an important role in mediating dynein-dependent transport of RAB8A-positive vesicles to the midbody during cytokinesis.	0.579
CCDC73	DEPDC7	ENSP00000335325	ENSP00000241051	Coiled-coil domain containing 73.	DEP domain containing 7; Belongs to the DEPDC7 family.	0.556
CCDC73	IMMP1L	ENSP00000335325	ENSP00000278200	Coiled-coil domain containing 73.	Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.	0.418
CCDC73	PRRG4	ENSP00000335325	ENSP00000257836	Coiled-coil domain containing 73.	Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family.	0.605
CCDC73	QSER1	ENSP00000335325	ENSP00000382241	Coiled-coil domain containing 73.	Glutamine and serine rich 1.	0.612
CCDC73	TCP11L1	ENSP00000335325	ENSP00000335595	Coiled-coil domain containing 73.	T-complex protein 11-like protein 1; T-complex 11 like 1.	0.644
DCDC1	CCDC73	ENSP00000385936	ENSP00000335325	Doublecortin domain-containing protein 1; Microtubule-binding protein which plays an important role in mediating dynein-dependent transport of RAB8A-positive vesicles to the midbody during cytokinesis.	Coiled-coil domain containing 73.	0.579
DCDC1	DNAJC24	ENSP00000385936	ENSP00000417548	Doublecortin domain-containing protein 1; Microtubule-binding protein which plays an important role in mediating dynein-dependent transport of RAB8A-positive vesicles to the midbody during cytokinesis.	DnaJ homolog subfamily C member 24; Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta); Belongs to the DPH4 family.	0.932
DCDC1	IMMP1L	ENSP00000385936	ENSP00000278200	Doublecortin domain-containing protein 1; Microtubule-binding protein which plays an important role in mediating dynein-dependent transport of RAB8A-positive vesicles to the midbody during cytokinesis.	Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.	0.907
DCDC1	KRT12	ENSP00000385936	ENSP00000251643	Doublecortin domain-containing protein 1; Microtubule-binding protein which plays an important role in mediating dynein-dependent transport of RAB8A-positive vesicles to the midbody during cytokinesis.	Keratin, type I cytoskeletal 12; May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity (By similarity).	0.497
DCDC1	MPPED2	ENSP00000385936	ENSP00000350833	Doublecortin domain-containing protein 1; Microtubule-binding protein which plays an important role in mediating dynein-dependent transport of RAB8A-positive vesicles to the midbody during cytokinesis.	Metallophosphoesterase MPPED2; Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system.	0.905
DEPDC7	C11orf91	ENSP00000241051	ENSP00000368296	DEP domain containing 7; Belongs to the DEPDC7 family.	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	0.418
DEPDC7	CCDC73	ENSP00000241051	ENSP00000335325	DEP domain containing 7; Belongs to the DEPDC7 family.	Coiled-coil domain containing 73.	0.556