Your Input: | |||||
| RALGAPA2 | Ral GTPase-activating protein subunit alpha-2; Catalytic subunit of the heterodimeric RalGAP2 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB. (1873 aa) | ||||
| ZNF500 | Zinc finger protein 500; May be involved in transcriptional regulation. (480 aa) | ||||
| RALGPS1 | Ras-specific guanine nucleotide-releasing factor RalGPS1; Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for. (557 aa) | ||||
| RALGAPB | Ral GTPase-activating protein subunit beta; Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators for the Ras-like small GTPases RALA and RALB. (1494 aa) | ||||
| GFOD2 | Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly. (385 aa) | ||||
| JAZF1 | Juxtaposed with another zinc finger protein 1; Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2. Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity (By similarity). Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD (By similarity). Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue (By similarity). Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity (By simi [...] (243 aa) | ||||
| NKIRAS2 | NF-kappa-B inhibitor-interacting Ras-like protein 2; Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity); Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. (191 aa) | ||||
| NR2C1 | Nuclear receptor subfamily 2 group C member 1; Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiatio [...] (603 aa) | ||||
| EZHIP | EZH inhibitory protein; Inhibits PRC2/EED-EZH2 complex function thereby causing down- regulation of H3K27me3. In the PRC2/EED-EZH2 complex, interacts and inhibits EZH2 methyltransferase activity. (503 aa) | ||||
| ZC3H7B | Zinc finger CCCH domain-containing protein 7B; May be a specific regulator of miRNA biogenesis. Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 'ATA(A/T)' motif in the apical loop. (977 aa) | ||||
| DUSP19 | Dual specificity protein phosphatase 19; Has a dual specificity toward Ser/Thr and Tyr-containing proteins. (217 aa) | ||||
| NUTM2G | NUT family member 2G. (741 aa) | ||||
| FOXJ3 | Forkhead box protein J3; Transcriptional activator of MEF2C involved in the regulation pf adult muscle fiber type identity and skeletal muscle regeneration. (622 aa) | ||||
| GARNL3 | GTPase-activating Rap/Ran-GAP domain-like protein 3; GTPase activating Rap/RanGAP domain like 3. (1013 aa) | ||||
| CCNB3 | G2/mitotic-specific cyclin-B3; Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I. (1395 aa) | ||||
| GFOD1 | Glucose-fructose oxidoreductase domain containing 1; Belongs to the Gfo/Idh/MocA family. (390 aa) | ||||
| MAP7D2 | MAP7 domain containing 2. (773 aa) | ||||
| NUTM2A | NUT family member 2A. (878 aa) | ||||
| ZNF816-ZNF321P | ZNF816-ZNF321P readthrough. (233 aa) | ||||
| ZC3H7A | Zinc finger CCCH domain-containing protein 7A; May be a specific regulator of miRNA biogenesis. Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 3'- ATA(A/T)-5' motif in the apical loop. (971 aa) | ||||
| NUTM2B | NUT family member 2B. (878 aa) | ||||
| NR2C2AP | Nuclear receptor 2C2-associated protein; May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes; Belongs to the NR2C2AP family. (167 aa) | ||||
| NUTM2E | NUT family member 2E; Belongs to the NUT family. (878 aa) | ||||
| NUGGC | Nuclear GTPase SLIP-GC; Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA. Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity). (796 aa) | ||||
| FKBP9 | Peptidyl-prolyl cis-trans isomerase FKBP9; PPIases accelerate the folding of proteins during protein synthesis. (623 aa) | ||||
| ADIG | Adipogenin; Plays a role in stimulating adipocyte differentiation and development; Belongs to the adipogenin family. (80 aa) | ||||
| EML5 | Echinoderm microtubule-associated protein-like 5; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic. (1977 aa) | ||||
| NR2C2 | Nuclear receptor subfamily 2 group C member 2; Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response element [...] (615 aa) | ||||
| RALGAPA1 | Ral GTPase-activating protein subunit alpha-1; Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB. (2495 aa) | ||||