STRINGSTRING
ZNF264 ZNF264 ZBTB21 ZBTB21 GPM6B GPM6B CRELD1 CRELD1 ARHGAP6 ARHGAP6 C2CD2 C2CD2 EGFL6 EGFL6 HCCS HCCS SHROOM2 SHROOM2 N4BP2L2 N4BP2L2 ZNF805 ZNF805 TCEANC TCEANC FAM9A FAM9A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZNF264Zinc finger protein 264; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (627 aa)
ZBTB21Zinc finger and BTB domain-containing protein 21; Acts as a transcription repressor. (1066 aa)
GPM6BNeuronal membrane glycoprotein M6-b; May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake. (328 aa)
CRELD1Protein disulfide isomerase CRELD1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane (By similarity); Belongs to the CRELD family. (422 aa)
ARHGAP6Rho GTPase-activating protein 6; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology. (974 aa)
C2CD2C2 calcium dependent domain containing 2. (696 aa)
EGFL6Epidermal growth factor-like protein 6; May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity). Belongs to the nephronectin family. (554 aa)
HCCSCytochrome c-type heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (268 aa)
SHROOM2Protein Shroom2; May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity). Belongs to the shroom family. (1616 aa)
N4BP2L2NEDD4 binding protein 2 like 2. (752 aa)
ZNF805Zinc finger protein 805; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (627 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (381 aa)
FAM9AProtein FAM9A; Family with sequence similarity 9 member A. (332 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.