(3 nodes) Congenital disorder of glycosylation type IIh network (Homo sapiens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	COG1	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function. (980 aa)
	COG7	Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function. (770 aa)
	COG8	Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. (612 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COG1	COG7	ENSP00000299886	ENSP00000305442	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.	0.999
COG1	COG8	ENSP00000299886	ENSP00000497669	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.	0.999
COG7	COG1	ENSP00000305442	ENSP00000299886	Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	0.999
COG7	COG8	ENSP00000305442	ENSP00000497669	Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.	0.999
COG8	COG1	ENSP00000497669	ENSP00000299886	Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	0.999
COG8	COG7	ENSP00000497669	ENSP00000305442	Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.	0.999