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DUT | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (252 aa) | ||||
DCTD | Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase. (189 aa) | ||||
SHMT1 | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. (483 aa) | ||||
TYMS | Thymidylate synthase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. (313 aa) |