STRINGSTRING
MYL6B MYL6B ACTC1 ACTC1 MYL1 MYL1 MYLPF MYLPF MYH7 MYH7 MYH3 MYH3 TPM1 TPM1 MYH2 MYH2 TNNT2 TNNT2 MYH8 MYH8 MYH6 MYH6 MYL6 MYL6 MYH4 MYH4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYL6BMyosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium. (208 aa)
ACTC1Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (377 aa)
MYL1Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. (194 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (169 aa)
MYH7Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. (1935 aa)
MYH3Myosin-3; Muscle contraction. (1940 aa)
TPM1Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. (284 aa)
MYH2Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity). (1941 aa)
TNNT2Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (298 aa)
MYH8Myosin-8; Muscle contraction. (1937 aa)
MYH6Myosin-6; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
MYL6Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium. (151 aa)
MYH4Myosin-4; Muscle contraction. (1939 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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