STRINGSTRING
H4C8 H4C8 H4C5 H4C5 H2AC4 H2AC4 H4C9 H4C9 H4C13 H4C13 H4C12 H4C12 H4C4 H4C4 H4C1 H4C1 H2BC11 H2BC11 H4C14 H4C14 H4C15 H4C15 H4-16 H4-16 H4C3 H4C3 H4C2 H4C2 H4C11 H4C11 CENPA CENPA H2AC8 H2AC8 H4C6 H4C6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H4C8H4 clustered histone 8. (103 aa)
H4C5H4 clustered histone 5. (103 aa)
H2AC4H2A clustered histone 4. (130 aa)
H4C9H4 clustered histone 9. (103 aa)
H4C13H4 clustered histone 13. (103 aa)
H4C12H4 clustered histone 12. (103 aa)
H4C4H4 clustered histone 4. (103 aa)
H4C1H4 clustered histone 1. (103 aa)
H2BC11Histone H2B type 1-J; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (126 aa)
H4C14H4 clustered histone 14. (103 aa)
H4C15H4 clustered histone 15. (103 aa)
H4-16H4 histone 16. (103 aa)
H4C3H4 clustered histone 3. (103 aa)
H4C2H4 clustered histone 2. (103 aa)
H4C11H4 clustered histone 11. (103 aa)
CENPAHistone H3-like centromeric protein A; Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. Required [...] (140 aa)
H2AC8Histone H2A type 1-B/E; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (130 aa)
H4C6Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.