Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GPR34 | P2RY12 | ENSP00000367384 | ENSP00000307259 | Probable G-protein coupled receptor 34; Orphan receptor. | P2Y purinoceptor 12; Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. | 0.474 |
| GPR87 | P2RY10 | ENSP00000260843 | ENSP00000171757 | G-protein coupled receptor 87; Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage. Belongs to the G-protein coupled receptor 1 family. | Putative P2Y purinoceptor 10; Putative receptor for purines coupled to G-proteins. | 0.438 |
| P2RY1 | P2RY10 | ENSP00000304767 | ENSP00000171757 | P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. | Putative P2Y purinoceptor 10; Putative receptor for purines coupled to G-proteins. | 0.474 |
| P2RY1 | P2RY11 | ENSP00000304767 | ENSP00000323872 | P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. | P2Y purinoceptor 11; Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. | 0.532 |
| P2RY1 | P2RY12 | ENSP00000304767 | ENSP00000307259 | P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. | P2Y purinoceptor 12; Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. | 0.957 |
| P2RY1 | P2RY13 | ENSP00000304767 | ENSP00000320376 | P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. | P2Y purinoceptor 13; Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. | 0.447 |
| P2RY1 | P2RY14 | ENSP00000304767 | ENSP00000308361 | P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. | P2Y purinoceptor 14; Receptor for UDP-glucose and other UDP-sugar coupled to G- proteins. Not activated by ATP, ADP, UTP or ATP. | 0.484 |
| P2RY1 | P2RY2 | ENSP00000304767 | ENSP00000310305 | P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. | P2Y purinoceptor 2; Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP. | 0.679 |
| P2RY1 | P2RY6 | ENSP00000304767 | ENSP00000480966 | P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. | P2Y purinoceptor 6; Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. | 0.489 |
| P2RY10 | GPR87 | ENSP00000171757 | ENSP00000260843 | Putative P2Y purinoceptor 10; Putative receptor for purines coupled to G-proteins. | G-protein coupled receptor 87; Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage. Belongs to the G-protein coupled receptor 1 family. | 0.438 |
| P2RY10 | P2RY1 | ENSP00000171757 | ENSP00000304767 | Putative P2Y purinoceptor 10; Putative receptor for purines coupled to G-proteins. | P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. | 0.474 |
| P2RY10 | P2RY11 | ENSP00000171757 | ENSP00000323872 | Putative P2Y purinoceptor 10; Putative receptor for purines coupled to G-proteins. | P2Y purinoceptor 11; Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. | 0.514 |
| P2RY10 | P2RY2 | ENSP00000171757 | ENSP00000310305 | Putative P2Y purinoceptor 10; Putative receptor for purines coupled to G-proteins. | P2Y purinoceptor 2; Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP. | 0.632 |
| P2RY10 | P2RY6 | ENSP00000171757 | ENSP00000480966 | Putative P2Y purinoceptor 10; Putative receptor for purines coupled to G-proteins. | P2Y purinoceptor 6; Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. | 0.481 |
| P2RY11 | P2RY1 | ENSP00000323872 | ENSP00000304767 | P2Y purinoceptor 11; Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. | P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. | 0.532 |
| P2RY11 | P2RY10 | ENSP00000323872 | ENSP00000171757 | P2Y purinoceptor 11; Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. | Putative P2Y purinoceptor 10; Putative receptor for purines coupled to G-proteins. | 0.514 |
| P2RY11 | P2RY13 | ENSP00000323872 | ENSP00000320376 | P2Y purinoceptor 11; Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. | P2Y purinoceptor 13; Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. | 0.882 |
| P2RY11 | P2RY2 | ENSP00000323872 | ENSP00000310305 | P2Y purinoceptor 11; Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. | P2Y purinoceptor 2; Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP. | 0.726 |
| P2RY11 | P2RY4 | ENSP00000323872 | ENSP00000363643 | P2Y purinoceptor 11; Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. | P2Y purinoceptor 4; Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP. | 0.566 |
| P2RY11 | P2RY6 | ENSP00000323872 | ENSP00000480966 | P2Y purinoceptor 11; Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. | P2Y purinoceptor 6; Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. | 0.724 |
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