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MRPS10 MRPS10 MRPS35 MRPS35 MRPS34 MRPS34 MTFMT MTFMT MRPL32 MRPL32 MRPL27 MRPL27 MRPL51 MRPL51 MRPS7 MRPS7 MRPL34 MRPL34 MRPS25 MRPS25 PTCD3 PTCD3 ERAL1 ERAL1 MRPS36 MRPS36 MRPL53 MRPL53 MRPL44 MRPL44 MRPS9 MRPS9 MRPS18B MRPS18B MRPL15 MRPL15 MTIF2 MTIF2 MRPL3 MRPL3 MRPS5 MRPS5 MRPS28 MRPS28 MRPL49 MRPL49 MRPS17 MRPS17 OXA1L OXA1L MRPL17 MRPL17 MRPL10 MRPL10 MRPS18C MRPS18C MRPL33 MRPL33 MRPL16 MRPL16 MRPL58 MRPL58 MRPL39 MRPL39 MRPL13 MRPL13 MRPL4 MRPL4 MRPL38 MRPL38 MRPL48 MRPL48 MRPL11 MRPL11 MRPL57 MRPL57 MRPL46 MRPL46 MRPL1 MRPL1 MRPS31 MRPS31 MRPS11 MRPS11 MRPS24 MRPS24 MRPS23 MRPS23 MRPS33 MRPS33 GADD45GIP1 GADD45GIP1 MRPL54 MRPL54 MRPL40 MRPL40 MRPL12 MRPL12 MRPL30 MRPL30 MRPL35 MRPL35 MRPL43 MRPL43 MRPL20 MRPL20 AURKAIP1 AURKAIP1 MRPL52 MRPL52 MRPL24 MRPL24 MRPL21 MRPL21 MRPL18 MRPL18 DAP3 DAP3 MRPL9 MRPL9 MRPL41 MRPL41 MRPS2 MRPS2 MRPL14 MRPL14 MRPS18A MRPS18A CHCHD1 CHCHD1 MRPS16 MRPS16 MRPS15 MRPS15 MRPL50 MRPL50 MRPS26 MRPS26 MTIF3 MTIF3 MRPL2 MRPL2 MRPL19 MRPL19 MRPL23 MRPL23 MRPS6 MRPS6 MRPS12 MRPS12 MRPL55 MRPL55 MRPL47 MRPL47 MRPS22 MRPS22 MRPS14 MRPS14 MRPL36 MRPL36 MRPS30 MRPS30 MRPS27 MRPS27 MRPL22 MRPL22 MRPL42 MRPL42 MRPS21 MRPS21 MRPL37 MRPL37 MRPL45 MRPL45 MRPL28 MRPL28
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MRPS10Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family. (201 aa)
MRPS35Mitochondrial ribosomal protein S35. (323 aa)
MRPS3428S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation. Belongs to the mitochondrion-specific ribosomal protein mS34 family. (225 aa)
MTFMTMethionyl-tRNA formyltransferase, mitochondrial; Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism (By similarity). (389 aa)
MRPL32Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (188 aa)
MRPL27Mitochondrial ribosomal protein L27. (148 aa)
MRPL51Mitochondrial ribosomal protein L51; Belongs to the mitochondrion-specific ribosomal protein mL51 family. (128 aa)
MRPS7Mitochondrial ribosomal protein S7. (242 aa)
MRPL34Mitochondrial ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (92 aa)
MRPS25Mitochondrial ribosomal protein S25. (173 aa)
PTCD3Pentatricopeptide repeat domain-containing protein 3, mitochondrial; Mitochondrial RNA-binding protein that has a role in mitochondrial translation. (689 aa)
ERAL1GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. (437 aa)
MRPS36Mitochondrial ribosomal protein S36. (103 aa)
MRPL53Mitochondrial ribosomal protein L53. (112 aa)
MRPL4439S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome. (332 aa)
MRPS9Mitochondrial ribosomal protein S9. (396 aa)
MRPS18BMitochondrial ribosomal protein S18B; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily. (258 aa)
MRPL15Mitochondrial ribosomal protein L15. (296 aa)
MTIF2Translation initiation factor IF-2, mitochondrial; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (727 aa)
MRPL3Mitochondrial ribosomal protein L3. (348 aa)
MRPS5Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family. (430 aa)
MRPS28Mitochondrial ribosomal protein S28; Belongs to the bacterial ribosomal protein bS1 family. (187 aa)
MRPL49Mitochondrial ribosomal protein L49. (166 aa)
MRPS17Mitochondrial ribosomal protein S17; Belongs to the universal ribosomal protein uS17 family. (130 aa)
OXA1LMitochondrial inner membrane protein OXA1L; Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria. Belongs to the OXA1/ALB3/YidC family. (495 aa)
MRPL17Mitochondrial ribosomal protein L17. (175 aa)
MRPL10Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family. (271 aa)
MRPS18CMitochondrial ribosomal protein S18C. (142 aa)
MRPL33Mitochondrial ribosomal protein L33. (65 aa)
MRPL16Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family. (251 aa)
MRPL58Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. (206 aa)
MRPL39Mitochondrial ribosomal protein L39; Belongs to the mitochondrion-specific ribosomal protein mL39 family. (353 aa)
MRPL13Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family. (178 aa)
MRPL4Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family. (311 aa)
MRPL38Mitochondrial ribosomal protein L38; Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily. (380 aa)
MRPL48Mitochondrial ribosomal protein L48. (212 aa)
MRPL11Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family. (192 aa)
MRPL57Mitochondrial ribosomal protein L57; Belongs to the mitochondrion-specific ribosomal protein mL63 family. (102 aa)
MRPL46Mitochondrial ribosomal protein L46; Belongs to the mitochondrion-specific ribosomal protein mL46 family. (279 aa)
MRPL1Mitochondrial ribosomal protein L1. (325 aa)
MRPS31Mitochondrial ribosomal protein S31. (395 aa)
MRPS11Mitochondrial ribosomal protein S11. (194 aa)
MRPS24Mitochondrial ribosomal protein S24; Belongs to the universal ribosomal protein uS3 family. (167 aa)
MRPS23Mitochondrial ribosomal protein S23; Belongs to the mitochondrion-specific ribosomal protein mS23 family. (190 aa)
MRPS33Mitochondrial ribosomal protein S33; Belongs to the mitochondrion-specific ribosomal protein mS33 family. (106 aa)
GADD45GIP1Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...] (222 aa)
MRPL54Mitochondrial ribosomal protein L54. (138 aa)
MRPL40Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family. (206 aa)
MRPL1239S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. (198 aa)
MRPL30Mitochondrial ribosomal protein L30. (161 aa)
MRPL35Mitochondrial ribosomal protein L35. (188 aa)
MRPL43Mitochondrial ribosomal protein L43. (235 aa)
MRPL20Mitochondrial ribosomal protein L20. (149 aa)
AURKAIP1Aurora kinase A-interacting protein; May act as a negative regulator of Aurora-A kinase, by down- regulation through proteasome-dependent degradation. (199 aa)
MRPL52Mitochondrial ribosomal protein L52. (123 aa)
MRPL24Mitochondrial ribosomal protein L24; Belongs to the universal ribosomal protein uL24 family. (216 aa)
MRPL21Mitochondrial ribosomal protein L21. (205 aa)
MRPL1839S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. (180 aa)
DAP328S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family. (398 aa)
MRPL9Mitochondrial ribosomal protein L9. (267 aa)
MRPL4139S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins. (137 aa)
MRPS228S ribosomal protein S2, mitochondrial; Required for mitoribosome formation and stability, and mitochondrial translation; Belongs to the universal ribosomal protein uS2 family. (296 aa)
MRPL1439S ribosomal protein L14, mitochondrial; Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable). (145 aa)
MRPS18AMitochondrial ribosomal protein S18A; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily. (196 aa)
CHCHD1Coiled-coil-helix-coiled-coil-helix domain containing 1. (118 aa)
MRPS16Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (137 aa)
MRPS15Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family. (257 aa)
MRPL50Mitochondrial ribosomal protein L50. (158 aa)
MRPS26Mitochondrial ribosomal protein S26; Belongs to the mitochondrion-specific ribosomal protein mS26 family. (205 aa)
MTIF3Translation initiation factor IF-3, mitochondrial; IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. (278 aa)
MRPL2Mitochondrial ribosomal protein L2; Belongs to the universal ribosomal protein uL2 family. (305 aa)
MRPL19Mitochondrial ribosomal protein L19. (292 aa)
MRPL23Mitochondrial ribosomal protein L23. (153 aa)
MRPS6Mitochondrial ribosomal protein S6. (125 aa)
MRPS12Mitochondrial ribosomal protein S12. (138 aa)
MRPL55Mitochondrial ribosomal protein L55. (164 aa)
MRPL47Mitochondrial ribosomal protein L47; Belongs to the universal ribosomal protein uL29 family. (250 aa)
MRPS22Mitochondrial ribosomal protein S22. (360 aa)
MRPS14Mitochondrial ribosomal protein S14. (128 aa)
MRPL36Mitochondrial ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (103 aa)
MRPS30Mitochondrial ribosomal protein S30. (439 aa)
MRPS2728S ribosomal protein S27, mitochondrial; RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth. (428 aa)
MRPL22Mitochondrial ribosomal protein L22. (206 aa)
MRPL42Mitochondrial ribosomal protein L42; Belongs to the mitochondrion-specific ribosomal protein mL42 family. (142 aa)
MRPS21Mitochondrial ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (87 aa)
MRPL37Mitochondrial ribosomal protein L37; Belongs to the mitochondrion-specific ribosomal protein mL37 family. (483 aa)
MRPL45Mitochondrial ribosomal protein L45. (306 aa)
MRPL28Mitochondrial ribosomal protein L28. (256 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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