STRINGSTRING
ZNF444 ZNF444 MZF1 MZF1 ZNF263 ZNF263 ZNF500 ZNF500 ZNF232 ZNF232 PGBD1 PGBD1 ZNF174 ZNF174 ZKSCAN7 ZKSCAN7 ZNF215 ZNF215 ZSCAN1 ZSCAN1 ZSCAN23 ZSCAN23 ZSCAN21 ZSCAN21 ZNF496 ZNF496 ZNF483 ZNF483 ZNF18 ZNF18 ZNF394 ZNF394 ZSCAN26 ZSCAN26 ZNF274 ZNF274 ZNF446 ZNF446 ZSCAN18 ZSCAN18 ZNF396 ZNF396 ZSCAN5B ZSCAN5B ZSCAN10 ZSCAN10 ZSCAN5C ZSCAN5C ZNF202 ZNF202 ZSCAN2 ZSCAN2 ZSCAN9 ZSCAN9 ZBED9 ZBED9 ZSCAN30 ZSCAN30 ZSCAN31 ZSCAN31 ZNF24 ZNF24 ZSCAN29 ZSCAN29 ZNF213 ZNF213 ZSCAN32 ZSCAN32 ZNF445 ZNF445 ZNF287 ZNF287 ZKSCAN5 ZKSCAN5 ZSCAN25 ZSCAN25 ZSCAN5A ZSCAN5A ZNF165 ZNF165 ZSCAN16 ZSCAN16 ZKSCAN4 ZKSCAN4 ZKSCAN3 ZKSCAN3 SCAND1 SCAND1 ZNF75D ZNF75D ZSCAN20 ZSCAN20 ZFP69B ZFP69B ZSCAN12 ZSCAN12 ZNF197 ZNF197 ZNF449 ZNF449 ZKSCAN8 ZKSCAN8 ZSCAN22 ZSCAN22 ZKSCAN2 ZKSCAN2 ZNF397 ZNF397 PEG3 PEG3 ZKSCAN1 ZKSCAN1 ZSCAN4 ZSCAN4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZNF444Zinc finger protein 444; Transcriptional regulator. Binds to the 5'-flanking critical region of the SCARF1 promoter; Belongs to the krueppel C2H2-type zinc-finger protein family. (327 aa)
MZF1Myeloid zinc finger 1; Binds to target promoter DNA and functions as transcription regulator. Regulates transcription from the PADI1 and CDH2 promoter. May be one regulator of transcriptional events during hemopoietic development; Belongs to the krueppel C2H2-type zinc-finger protein family. (734 aa)
ZNF263Zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family. (683 aa)
ZNF500Zinc finger protein 500; May be involved in transcriptional regulation. (480 aa)
ZNF232Zinc finger protein 232; May be involved in transcriptional regulation. (444 aa)
PGBD1piggyBac transposable element derived 1. (809 aa)
ZNF174Zinc finger protein 174; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family. (407 aa)
ZKSCAN7Zinc finger protein with KRAB and SCAN domains 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (754 aa)
ZNF215Zinc finger protein 215; May be involved in transcriptional regulation. (517 aa)
ZSCAN1Zinc finger and SCAN domain-containing protein 1; May be involved in transcriptional regulation. (408 aa)
ZSCAN23Zinc finger and SCAN domain-containing protein 23; May be involved in transcriptional regulation. (389 aa)
ZSCAN21Zinc finger and SCAN domain-containing protein 21; Strong transcriptional activator. (473 aa)
ZNF496Zinc finger protein 496; DNA-binding transcription factor that can both act as an activator and a repressor; Belongs to the krueppel C2H2-type zinc-finger protein family. (587 aa)
ZNF483Zinc finger protein 483; May be involved in transcriptional regulation. (744 aa)
ZNF18Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (549 aa)
ZNF394Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (561 aa)
ZSCAN26Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. (478 aa)
ZNF274Neurotrophin receptor-interacting factor homolog; Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. The SETDB1-TRIM28-ZNF274 complex may play a role in recruiting ATRX to the 3'-exons of zinc-finger coding genes with atypical chromatin signatures to establish or maintain/protect H3K9me3 at these transcriptionally active regions. (653 aa)
ZNF446Zinc finger protein 446; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (450 aa)
ZSCAN18Zinc finger and SCAN domain-containing protein 18; May be involved in transcriptional regulation. (566 aa)
ZNF396Zinc finger protein 396; Isoform 1 and isoform 2 act as DNA-dependent transcriptional repressors. (335 aa)
ZSCAN5BZinc finger and SCAN domain-containing protein 5B; May be involved in transcriptional regulation. (495 aa)
ZSCAN10Zinc finger and SCAN domain-containing protein 10; Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can both activate and /or repress expression of target genes, depending on the context. Specifically binds the 5'-[GA]CGCNNGCG[CT]-3' DNA consensus sequence. Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4. (780 aa)
ZSCAN5CZinc finger and SCAN domain-containing protein 5C; May be involved in transcriptional regulation. (496 aa)
ZNF202Zinc finger protein 202; Transcriptional repressor that binds to elements found predominantly in genes that participate in lipid metabolism. Among its targets are structural components of lipoprotein particles (apolipoproteins AIV, CIII, and E), enzymes involved in lipid processing (lipoprotein lipase, lecithin cholesteryl ester transferase), transporters involved in lipid homeostasis (ABCA1, ABCG1), and several genes involved in processes related to energy metabolism and vascular disease. (648 aa)
ZSCAN2Zinc finger and SCAN domain-containing protein 2; May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis. (614 aa)
ZSCAN9Zinc finger and SCAN domain-containing protein 9; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (445 aa)
ZBED9SCAN domain-containing protein 3; Zinc finger BED-type containing 9. (1325 aa)
ZSCAN30Zinc finger and SCAN domain-containing protein 30; May be involved in transcriptional regulation. (494 aa)
ZSCAN31Zinc finger and SCAN domain-containing protein 31; May function as a transcription factor. May be involved in the development of multiple embryonic organs; Belongs to the krueppel C2H2-type zinc-finger protein family. (406 aa)
ZNF24Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro; Belongs to the krueppel C2H2-type zinc-finger protein family. (368 aa)
ZSCAN29Zinc finger and SCAN domain-containing protein 29; May be involved in transcriptional regulation. (852 aa)
ZNF213Zinc finger protein 213; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (459 aa)
ZSCAN32Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (697 aa)
ZNF445Zinc finger protein 445; Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs). Acts together with ZFP57, but seems to be the major factor in human early embryonic imprinting maintenance. In contrast, in mice, ZFP57 plays the predominant role in imprint [...] (1031 aa)
ZNF287Zinc finger protein 287; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (761 aa)
ZKSCAN5Zinc finger protein with KRAB and SCAN domains 5; May be involved in transcriptional regulation. (839 aa)
ZSCAN25Zinc finger and SCAN domain-containing protein 25; May be involved in transcriptional regulation. (544 aa)
ZSCAN5AZinc finger and SCAN domain-containing protein 5A; May be involved in transcriptional regulation. (496 aa)
ZNF165Zinc finger protein 165; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (485 aa)
ZSCAN16Zinc finger and SCAN domain-containing protein 16; May be involved in transcriptional regulation. (348 aa)
ZKSCAN4Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. (545 aa)
ZKSCAN3Zinc finger protein with KRAB and SCAN domains 3; Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas. (538 aa)
SCAND1SCAN domain-containing protein 1; May regulate transcriptional activity. (179 aa)
ZNF75DZinc finger protein 75D; May be involved in transcriptional regulation. (510 aa)
ZSCAN20Zinc finger and SCAN domain-containing protein 20; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (1043 aa)
ZFP69BZinc finger protein 69 homolog B; May be involved in transcriptional regulation. Essential for Golgi structural integrity. (534 aa)
ZSCAN12Zinc finger and SCAN domain-containing protein 12; May be involved in transcriptional regulation. (604 aa)
ZNF197Zinc finger protein 197; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (1029 aa)
ZNF449Zinc finger protein 449; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (518 aa)
ZKSCAN8Zinc finger protein with KRAB and SCAN domains 8; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (578 aa)
ZSCAN22Zinc finger and SCAN domain-containing protein 22; May be involved in transcriptional regulation. (491 aa)
ZKSCAN2Zinc finger protein with KRAB and SCAN domains 2; May be involved in transcriptional regulation. (967 aa)
ZNF397Zinc finger protein 397; Isoform 3 acts as a DNA-dependent transcriptional repressor. (534 aa)
PEG3Paternally-expressed gene 3 protein; Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells; Belongs to the krueppel C2H2-type zinc-finger protein family. (1588 aa)
ZKSCAN1Zinc finger protein with KRAB and SCAN domains 1; May be involved in transcriptional regulation. (563 aa)
ZSCAN4Zinc finger and SCAN domain-containing protein 4; Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity). (433 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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