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| WDR43 | WD repeat-containing protein 43; Ribosome biogenesis factor that coordinates hyperactive transcription and ribogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Essential for stem cell pluripotency and embryonic development. In the nucleoplasm, recruited by promoter-associated/nascent transcripts and transcription to active promoters where it facilitates releases of elongation factor P-TEFb and paused RNA polymerase II to allow transcription elongation and maintain high-level expression of its t [...] (677 aa) | ||||
| WDR3 | WD repeat domain 3; Belongs to the WD repeat WDR3/UTP12 family. (943 aa) | ||||
| PWP2 | Periodic tryptophan protein 2 homolog; PWP2 small subunit processome component. (919 aa) | ||||