STRINGSTRING
PI16 PI16 PI15 PI15 CRISPLD1 CRISPLD1 CRISPLD2 CRISPLD2 GLIPR1 GLIPR1 CRISP1 CRISP1 GLIPR2 GLIPR2 GLIPR1L1 GLIPR1L1 CRISP3 CRISP3 CRISP2 CRISP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PI16Peptidase inhibitor 16; May inhibit cardiomyocyte growth. (463 aa)
PI15Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family. (258 aa)
CRISPLD1Cysteine rich secretory protein LCCL domain containing 1; Belongs to the CRISP family. (500 aa)
CRISPLD2Cysteine-rich secretory protein LCCL domain-containing 2; Promotes matrix assembly; Belongs to the CRISP family. (497 aa)
GLIPR1Glioma pathogenesis-related protein 1; GLI pathogenesis related 1; Belongs to the CRISP family. (266 aa)
CRISP1Cysteine-rich secretory protein 1; May have a role in sperm-egg fusion and maturation; Belongs to the CRISP family. (249 aa)
GLIPR2Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2. (154 aa)
GLIPR1L1GLIPR1-like protein 1; Plays a role in the binding between sperm and oocytes. Component of epididymosomes, one type of membranous microvesicules which mediate the transfer of lipids and proteins to spermatozoa plasma membrane during epididymal maturation. Also component of the CD9- positive microvesicules found in the cauda region. (242 aa)
CRISP3Cysteine rich secretory protein 3; Belongs to the CRISP family. (268 aa)
CRISP2Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. (243 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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