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| EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. Belongs to the endothelin/sarafotoxin family. (212 aa) | ||||
| EDN2 | Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides. (178 aa) | ||||
| EDN3 | Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides. (238 aa) | ||||