STRINGSTRING
TRAPPC5 TRAPPC5 TRAPPC3 TRAPPC3 TRAPPC6B TRAPPC6B GUCY1A1 GUCY1A1 GUCY1A2 GUCY1A2 TRAPPC3L TRAPPC3L TRAPPC6A TRAPPC6A GUCY1B1 GUCY1B1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRAPPC5Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily. (188 aa)
TRAPPC3Trafficking protein particle complex subunit 3; May play a role in vesicular transport from endoplasmic reticulum to Golgi. (188 aa)
TRAPPC6BTrafficking protein particle complex subunit 6B; Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic. Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival (Probable). (158 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Has guanylyl cyclase on binding to the beta-1 subunit. (763 aa)
TRAPPC3LTrafficking protein particle complex subunit 3-like protein; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily. (181 aa)
TRAPPC6ATrafficking protein particle complex subunit 6A; May play a role in vesicular transport during the biogenesis of melanosomes. (173 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (641 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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