STRINGSTRING
KRT5 KRT5 KRT72 KRT72 KRT83 KRT83 KRT71 KRT71 KRT82 KRT82 KRT84 KRT84 KRT85 KRT85 KRT6B KRT6B KRT6C KRT6C KRT75 KRT75 KRT1 KRT1 KRT8 KRT8 KRT4 KRT4 KRT86 KRT86 KRT3 KRT3 KRT81 KRT81 KRT6A KRT6A KRT77 KRT77 KRT76 KRT76 KRT7 KRT7 KRT79 KRT79 KRT2 KRT2 KRT74 KRT74 KRT73 KRT73 KRT78 KRT78
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KRT5Keratin, type II cytoskeletal 5; Keratin 5; Belongs to the intermediate filament family. (590 aa)
KRT72Keratin, type II cytoskeletal 72; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). (511 aa)
KRT83Keratin, type II cuticular Hb3; Keratin 83; Belongs to the intermediate filament family. (493 aa)
KRT71Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. (523 aa)
KRT82Keratin, type II cuticular Hb2; Keratin 82; Belongs to the intermediate filament family. (513 aa)
KRT84Keratin, type II cuticular Hb4; Keratin 84. (600 aa)
KRT85Keratin, type II cuticular Hb5; Keratin 85; Belongs to the intermediate filament family. (507 aa)
KRT6BKeratin, type II cytoskeletal 6B; Keratin 6B; Belongs to the intermediate filament family. (564 aa)
KRT6CKeratin, type II cytoskeletal 6C; Keratin 6C; Belongs to the intermediate filament family. (564 aa)
KRT75Keratin, type II cytoskeletal 75; Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments in the companion layer of the hair follicle. (551 aa)
KRT1Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. (644 aa)
KRT8Keratin, type II cytoskeletal 8; Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. Belongs to the intermediate filament family. (511 aa)
KRT4Keratin, type II cytoskeletal 4; Keratin 4; Belongs to the intermediate filament family. (520 aa)
KRT86Keratin, type II cuticular Hb6. (486 aa)
KRT3Keratin, type II cytoskeletal 3; Keratin 3; Belongs to the intermediate filament family. (628 aa)
KRT81Keratin, type II cuticular Hb1; Keratin 81. (505 aa)
KRT6AKeratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Belongs to the intermediate filament family. (564 aa)
KRT77Keratin, type II cytoskeletal 1b; Keratin 77. (578 aa)
KRT76Keratin, type II cytoskeletal 2 oral; Probably contributes to terminal cornification. Belongs to the intermediate filament family. (638 aa)
KRT7Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family. (469 aa)
KRT79Keratin, type II cytoskeletal 79; Keratin 79; Belongs to the intermediate filament family. (535 aa)
KRT2Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). (639 aa)
KRT74Keratin, type II cytoskeletal 74; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). (529 aa)
KRT73Keratin, type II cytoskeletal 73; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). (540 aa)
KRT78Keratin, type II cytoskeletal 78; Keratin 78; Belongs to the intermediate filament family. (520 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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