Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADAM33 | DPP10 | ENSP00000348912 | ENSP00000376855 | Disintegrin and metalloproteinase domain-containing protein 33; ADAM metallopeptidase domain 33. | Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity. | 0.787 |
| ADAM33 | NPSR1 | ENSP00000348912 | ENSP00000370950 | Disintegrin and metalloproteinase domain-containing protein 33; ADAM metallopeptidase domain 33. | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE- mediated diseases. | 0.698 |
| ADAM33 | PHF11 | ENSP00000348912 | ENSP00000367570 | Disintegrin and metalloproteinase domain-containing protein 33; ADAM metallopeptidase domain 33. | PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression. | 0.905 |
| ADAM33 | SPINK5 | ENSP00000348912 | ENSP00000352936 | Disintegrin and metalloproteinase domain-containing protein 33; ADAM metallopeptidase domain 33. | Serine protease inhibitor Kazal-type 5; Serine protease inhibitor, probably important for the anti- inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation- involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin. | 0.620 |
| DPP10 | ADAM33 | ENSP00000376855 | ENSP00000348912 | Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity. | Disintegrin and metalloproteinase domain-containing protein 33; ADAM metallopeptidase domain 33. | 0.787 |
| DPP10 | NPSR1 | ENSP00000376855 | ENSP00000370950 | Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity. | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE- mediated diseases. | 0.663 |
| DPP10 | PHF11 | ENSP00000376855 | ENSP00000367570 | Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity. | PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression. | 0.819 |
| DPP10 | SPINK5 | ENSP00000376855 | ENSP00000352936 | Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity. | Serine protease inhibitor Kazal-type 5; Serine protease inhibitor, probably important for the anti- inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation- involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin. | 0.523 |
| NPSR1 | ADAM33 | ENSP00000370950 | ENSP00000348912 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE- mediated diseases. | Disintegrin and metalloproteinase domain-containing protein 33; ADAM metallopeptidase domain 33. | 0.698 |
| NPSR1 | DPP10 | ENSP00000370950 | ENSP00000376855 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE- mediated diseases. | Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity. | 0.663 |
| NPSR1 | PHF11 | ENSP00000370950 | ENSP00000367570 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE- mediated diseases. | PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression. | 0.721 |
| PHF11 | ADAM33 | ENSP00000367570 | ENSP00000348912 | PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression. | Disintegrin and metalloproteinase domain-containing protein 33; ADAM metallopeptidase domain 33. | 0.905 |
| PHF11 | DPP10 | ENSP00000367570 | ENSP00000376855 | PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression. | Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity. | 0.819 |
| PHF11 | NPSR1 | ENSP00000367570 | ENSP00000370950 | PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression. | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE- mediated diseases. | 0.721 |
| PHF11 | SETDB2 | ENSP00000367570 | ENSP00000346175 | PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression. | Histone-lysine N-methyltransferase SETDB2; Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere- associated repeats. Plays a role in chromosome condensation and segregation during mitosis. | 0.989 |
| PHF11 | SPINK5 | ENSP00000367570 | ENSP00000352936 | PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression. | Serine protease inhibitor Kazal-type 5; Serine protease inhibitor, probably important for the anti- inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation- involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin. | 0.754 |
| SETDB2 | PHF11 | ENSP00000346175 | ENSP00000367570 | Histone-lysine N-methyltransferase SETDB2; Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere- associated repeats. Plays a role in chromosome condensation and segregation during mitosis. | PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression. | 0.989 |
| SPINK5 | ADAM33 | ENSP00000352936 | ENSP00000348912 | Serine protease inhibitor Kazal-type 5; Serine protease inhibitor, probably important for the anti- inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation- involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin. | Disintegrin and metalloproteinase domain-containing protein 33; ADAM metallopeptidase domain 33. | 0.620 |
| SPINK5 | DPP10 | ENSP00000352936 | ENSP00000376855 | Serine protease inhibitor Kazal-type 5; Serine protease inhibitor, probably important for the anti- inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation- involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin. | Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity. | 0.523 |
| SPINK5 | PHF11 | ENSP00000352936 | ENSP00000367570 | Serine protease inhibitor Kazal-type 5; Serine protease inhibitor, probably important for the anti- inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation- involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin. | PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression. | 0.754 |