19 items (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPL19	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (196 aa)
	CEBPZ	CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family. (1054 aa)
	RPL8	60S ribosomal protein L8; Component of the large ribosomal subunit. (257 aa)
	RPL15	Ribosomal protein L15. (204 aa)
	RPL4	Ribosomal protein L4. (427 aa)
	FTSJ1	Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily. (329 aa)
	PDCD11	Protein RRP5 homolog; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA. (1871 aa)
	RPL14	60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family. (215 aa)
	PWP1	Periodic tryptophan protein 1 homolog; Chromatin-associated factor that regulates transcription. Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription. Regulates the epigenetic status of rDNA. (501 aa)
	FTSJ3	pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. (847 aa)
	RPF2	Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus. (306 aa)
	RPL6	60S ribosomal protein L6; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL6 family. (288 aa)
	EBNA1BP2	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. (361 aa)
	RPL18	60S ribosomal protein L18; Component of the large ribosomal subunit. (188 aa)
	RPL36	60S ribosomal protein L36; Component of the large ribosomal subunit. (105 aa)
	NSA2	Ribosome biogenesis protein NSA2 homolog; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity). (260 aa)
	RPS7	40S ribosomal protein S7; Required for rRNA maturation. (194 aa)
	RPL35A	60S ribosomal protein L35a; Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site. (110 aa)
	SPTB	Spectrin beta chain, erythrocytic; Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. (2328 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEBPZ	EBNA1BP2	ENSP00000234170	ENSP00000407323	CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family.	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	0.968
CEBPZ	FTSJ1	ENSP00000234170	ENSP00000326948	CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family.	Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.	0.525
CEBPZ	FTSJ3	ENSP00000234170	ENSP00000396673	CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family.	pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.	0.929
CEBPZ	NSA2	ENSP00000234170	ENSP00000483484	CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family.	Ribosome biogenesis protein NSA2 homolog; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity).	0.745
CEBPZ	PDCD11	ENSP00000234170	ENSP00000358812	CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family.	Protein RRP5 homolog; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA.	0.999
CEBPZ	PWP1	ENSP00000234170	ENSP00000387365	CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family.	Periodic tryptophan protein 1 homolog; Chromatin-associated factor that regulates transcription. Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription. Regulates the epigenetic status of rDNA.	0.907
CEBPZ	RPF2	ENSP00000234170	ENSP00000402338	CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family.	Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.	0.975
CEBPZ	RPL18	ENSP00000234170	ENSP00000447001	CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family.	60S ribosomal protein L18; Component of the large ribosomal subunit.	0.445
EBNA1BP2	CEBPZ	ENSP00000407323	ENSP00000234170	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family.	0.968
EBNA1BP2	FTSJ1	ENSP00000407323	ENSP00000326948	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.	0.868
EBNA1BP2	FTSJ3	ENSP00000407323	ENSP00000396673	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.	0.999
EBNA1BP2	NSA2	ENSP00000407323	ENSP00000483484	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	Ribosome biogenesis protein NSA2 homolog; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity).	0.997
EBNA1BP2	PDCD11	ENSP00000407323	ENSP00000358812	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	Protein RRP5 homolog; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA.	0.922
EBNA1BP2	PWP1	ENSP00000407323	ENSP00000387365	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	Periodic tryptophan protein 1 homolog; Chromatin-associated factor that regulates transcription. Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription. Regulates the epigenetic status of rDNA.	0.981
EBNA1BP2	RPF2	ENSP00000407323	ENSP00000402338	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.	0.999
EBNA1BP2	RPL14	ENSP00000407323	ENSP00000379506	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family.	0.946
EBNA1BP2	RPL15	ENSP00000407323	ENSP00000309334	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	Ribosomal protein L15.	0.891
EBNA1BP2	RPL18	ENSP00000407323	ENSP00000447001	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	60S ribosomal protein L18; Component of the large ribosomal subunit.	0.924
EBNA1BP2	RPL19	ENSP00000407323	ENSP00000225430	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.875
EBNA1BP2	RPL35A	ENSP00000407323	ENSP00000495672	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA.	60S ribosomal protein L35a; Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site.	0.855