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CRX | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. Belongs to the paired homeobox family. (299 aa) | ||||
ATXN7 | Ataxin-7; Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtubule cytoskeleton stabilization. (892 aa) | ||||
ATXN7L2 | Ataxin-7-like protein 2; Ataxin 7 like 2. (722 aa) | ||||
ATXN7L1 | Ataxin-7-like protein 1; Ataxin 7 like 1. (861 aa) | ||||
ATXN7-2 | Ataxin 7. (945 aa) |