node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MUC1 | MUC13 | ENSP00000484824 | ENSP00000485028 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | 0.943 |
MUC1 | MUC15 | ENSP00000484824 | ENSP00000431983 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-15; May play a role in the cell adhesion to the extracellular matrix. | 0.970 |
MUC1 | MUC17 | ENSP00000484824 | ENSP00000302716 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-17; Probably plays a role in maintaining homeostasis on mucosal surfaces. | 0.896 |
MUC1 | MUC20 | ENSP00000484824 | ENSP00000414350 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. | 0.953 |
MUC1 | MUC21 | ENSP00000484824 | ENSP00000365473 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-21; Mucin 21, cell surface associated. | 0.819 |
MUC1 | MUC22 | ENSP00000484824 | ENSP00000455906 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-22; Mucin 22. | 0.599 |
MUC1 | MUC4 | ENSP00000484824 | ENSP00000417498 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-4 alpha chain; May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation. Has anti-adhesive properties. Seems to alter cellular behavior through both anti-adhesive effects on cell-cell and cell- extracellular matrix interactions and in its ability to act as an intramembrane ligand for ERBB2. Plays an important role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2. The MUC4-ERBB2 complex causes site- specific phosphorylation of the ERBB2 ' [...] | 0.990 |
MUC1 | MUC5AC | ENSP00000484824 | ENSP00000485659 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-5AC; Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD). | 0.987 |
MUC1 | MUC5B | ENSP00000484824 | ENSP00000436812 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-5B; Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. | 0.969 |
MUC1 | MUC6 | ENSP00000484824 | ENSP00000406861 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-6; May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. | 0.977 |
MUC1 | MUC7 | ENSP00000484824 | ENSP00000407422 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-7; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili. | 0.964 |
MUC13 | MUC1 | ENSP00000485028 | ENSP00000484824 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | 0.943 |
MUC13 | MUC15 | ENSP00000485028 | ENSP00000431983 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-15; May play a role in the cell adhesion to the extracellular matrix. | 0.940 |
MUC13 | MUC17 | ENSP00000485028 | ENSP00000302716 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-17; Probably plays a role in maintaining homeostasis on mucosal surfaces. | 0.969 |
MUC13 | MUC20 | ENSP00000485028 | ENSP00000414350 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. | 0.949 |
MUC13 | MUC21 | ENSP00000485028 | ENSP00000365473 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-21; Mucin 21, cell surface associated. | 0.915 |
MUC13 | MUC22 | ENSP00000485028 | ENSP00000455906 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-22; Mucin 22. | 0.645 |
MUC13 | MUC4 | ENSP00000485028 | ENSP00000417498 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-4 alpha chain; May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation. Has anti-adhesive properties. Seems to alter cellular behavior through both anti-adhesive effects on cell-cell and cell- extracellular matrix interactions and in its ability to act as an intramembrane ligand for ERBB2. Plays an important role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2. The MUC4-ERBB2 complex causes site- specific phosphorylation of the ERBB2 ' [...] | 0.965 |
MUC13 | MUC5AC | ENSP00000485028 | ENSP00000485659 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-5AC; Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD). | 0.946 |
MUC13 | MUC5B | ENSP00000485028 | ENSP00000436812 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-5B; Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. | 0.926 |