| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PRB1 | PRB2 | ENSP00000420826 | ENSP00000374013 | Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1. | Basic salivary proline-rich protein 2; Proline rich protein BstNI subfamily 2. | 0.909 |
| PRB1 | PRB3 | ENSP00000420826 | ENSP00000442626 | Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1. | Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum. | 0.817 |
| PRB1 | PRB4 | ENSP00000420826 | ENSP00000279575 | Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1. | Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4. | 0.999 |
| PRB1 | RB1 | ENSP00000420826 | ENSP00000267163 | Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1. | Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransfer [...] | 0.786 |
| PRB2 | PRB1 | ENSP00000374013 | ENSP00000420826 | Basic salivary proline-rich protein 2; Proline rich protein BstNI subfamily 2. | Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1. | 0.909 |
| PRB2 | RB1 | ENSP00000374013 | ENSP00000267163 | Basic salivary proline-rich protein 2; Proline rich protein BstNI subfamily 2. | Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransfer [...] | 0.680 |
| PRB3 | PRB1 | ENSP00000442626 | ENSP00000420826 | Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum. | Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1. | 0.817 |
| PRB3 | PRB4 | ENSP00000442626 | ENSP00000279575 | Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum. | Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4. | 0.999 |
| PRB3 | RB1 | ENSP00000442626 | ENSP00000267163 | Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum. | Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransfer [...] | 0.809 |
| PRB4 | PRB1 | ENSP00000279575 | ENSP00000420826 | Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4. | Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1. | 0.999 |
| PRB4 | PRB3 | ENSP00000279575 | ENSP00000442626 | Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4. | Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum. | 0.999 |
| PRB4 | RB1 | ENSP00000279575 | ENSP00000267163 | Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4. | Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransfer [...] | 0.780 |
| RB1 | PRB1 | ENSP00000267163 | ENSP00000420826 | Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransfer [...] | Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1. | 0.786 |
| RB1 | PRB2 | ENSP00000267163 | ENSP00000374013 | Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransfer [...] | Basic salivary proline-rich protein 2; Proline rich protein BstNI subfamily 2. | 0.680 |
| RB1 | PRB3 | ENSP00000267163 | ENSP00000442626 | Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransfer [...] | Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum. | 0.809 |
| RB1 | PRB4 | ENSP00000267163 | ENSP00000279575 | Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransfer [...] | Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4. | 0.780 |