6 items (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCN	Decorin; May affect the rate of fibrils formation. (359 aa)
	GLB1	Beta-galactosidase; [Isoform 1]: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. (677 aa)
	BGN	Biglycan; May be involved in collagen fiber assembly. (368 aa)
	ELN	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity). (786 aa)
	MFAP5	Microfibrillar-associated protein 5; May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils. (173 aa)
	MFAP2	Microfibrillar-associated protein 2; Component of the elastin-associated microfibrils; Belongs to the MFAP family. (183 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BGN	DCN	ENSP00000327336	ENSP00000052754	Biglycan; May be involved in collagen fiber assembly.	Decorin; May affect the rate of fibrils formation.	0.989
BGN	ELN	ENSP00000327336	ENSP00000351807	Biglycan; May be involved in collagen fiber assembly.	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).	0.990
BGN	GLB1	ENSP00000327336	ENSP00000306920	Biglycan; May be involved in collagen fiber assembly.	Beta-galactosidase; [Isoform 1]: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.	0.596
BGN	MFAP2	ENSP00000327336	ENSP00000364685	Biglycan; May be involved in collagen fiber assembly.	Microfibrillar-associated protein 2; Component of the elastin-associated microfibrils; Belongs to the MFAP family.	0.886
BGN	MFAP5	ENSP00000327336	ENSP00000352455	Biglycan; May be involved in collagen fiber assembly.	Microfibrillar-associated protein 5; May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils.	0.441
DCN	BGN	ENSP00000052754	ENSP00000327336	Decorin; May affect the rate of fibrils formation.	Biglycan; May be involved in collagen fiber assembly.	0.989
DCN	ELN	ENSP00000052754	ENSP00000351807	Decorin; May affect the rate of fibrils formation.	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).	0.993
DCN	MFAP2	ENSP00000052754	ENSP00000364685	Decorin; May affect the rate of fibrils formation.	Microfibrillar-associated protein 2; Component of the elastin-associated microfibrils; Belongs to the MFAP family.	0.954
DCN	MFAP5	ENSP00000052754	ENSP00000352455	Decorin; May affect the rate of fibrils formation.	Microfibrillar-associated protein 5; May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils.	0.490
ELN	BGN	ENSP00000351807	ENSP00000327336	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).	Biglycan; May be involved in collagen fiber assembly.	0.990
ELN	DCN	ENSP00000351807	ENSP00000052754	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).	Decorin; May affect the rate of fibrils formation.	0.993
ELN	GLB1	ENSP00000351807	ENSP00000306920	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).	Beta-galactosidase; [Isoform 1]: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.	0.987
ELN	MFAP2	ENSP00000351807	ENSP00000364685	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).	Microfibrillar-associated protein 2; Component of the elastin-associated microfibrils; Belongs to the MFAP family.	0.996
ELN	MFAP5	ENSP00000351807	ENSP00000352455	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).	Microfibrillar-associated protein 5; May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils.	0.882
GLB1	BGN	ENSP00000306920	ENSP00000327336	Beta-galactosidase; [Isoform 1]: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.	Biglycan; May be involved in collagen fiber assembly.	0.596
GLB1	ELN	ENSP00000306920	ENSP00000351807	Beta-galactosidase; [Isoform 1]: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).	0.987
MFAP2	BGN	ENSP00000364685	ENSP00000327336	Microfibrillar-associated protein 2; Component of the elastin-associated microfibrils; Belongs to the MFAP family.	Biglycan; May be involved in collagen fiber assembly.	0.886
MFAP2	DCN	ENSP00000364685	ENSP00000052754	Microfibrillar-associated protein 2; Component of the elastin-associated microfibrils; Belongs to the MFAP family.	Decorin; May affect the rate of fibrils formation.	0.954
MFAP2	ELN	ENSP00000364685	ENSP00000351807	Microfibrillar-associated protein 2; Component of the elastin-associated microfibrils; Belongs to the MFAP family.	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).	0.996
MFAP2	MFAP5	ENSP00000364685	ENSP00000352455	Microfibrillar-associated protein 2; Component of the elastin-associated microfibrils; Belongs to the MFAP family.	Microfibrillar-associated protein 5; May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils.	0.943