STRINGSTRING
XAGE5 XAGE5 PAGE5 PAGE5 XAGE2 XAGE2 PIWIL1 PIWIL1 PAGE4 PAGE4 GAGE12F GAGE12F GAGE1 GAGE1 GAGE13 GAGE13 GAGE2E GAGE2E GAGE12G GAGE12G GAGE12J GAGE12J GAGE12C GAGE12C GAGE10 GAGE10 GAGE12D GAGE12D GAGE12H GAGE12H GAGE12E GAGE12E PAGE1 PAGE1 PAGE2B PAGE2B PAGE2 PAGE2 PAGE3 PAGE3 GAGE2A GAGE2A XAGE3 XAGE3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XAGE5X antigen family member 5; Belongs to the GAGE family. (108 aa)
PAGE5PAGE family member 5; Belongs to the GAGE family. (130 aa)
XAGE2X antigen family member 2. (111 aa)
PIWIL1Piwi-like protein 1; Endoribonuclease that plays a central role in postnatal germ cells by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived fr [...] (861 aa)
PAGE4P antigen family member 4; Intrinsically disordered protein that potentiates the transcriptional activator activity of JUN. Protects cells from stress-induced apoptosis by inhibiting reactive oxygen species (ROS) production and via regulation of the MAPK signaling pathway. (102 aa)
GAGE12FG antigen 12F. (117 aa)
GAGE1G antigen 1; Antigen, recognized on melanoma by autologous cytolytic T- lymphocytes. Completely silent in normal adult tissues, except testis; Belongs to the GAGE family. (117 aa)
GAGE13G antigen 13. (117 aa)
GAGE2EG antigen 2E. (110 aa)
GAGE12GG antigen 12G. (117 aa)
GAGE12JG antigen 12J. (117 aa)
GAGE12CG antigen 12C. (117 aa)
GAGE10G antigen 10; Belongs to the GAGE family. (116 aa)
GAGE12DG antigen 12D. (117 aa)
GAGE12HG antigen 12H. (117 aa)
GAGE12EG antigen 12E; Belongs to the GAGE family. (117 aa)
PAGE1PAGE family member 1. (146 aa)
PAGE2BPAGE family member 2B; Belongs to the GAGE family. (111 aa)
PAGE2PAGE family member 2. (111 aa)
PAGE3PAGE family member 3. (113 aa)
GAGE2AG antigen 2A. (116 aa)
XAGE3X antigen family member 3. (111 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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