(8 nodes) Proline-rich network (Homo sapiens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRH2	Salivary acidic proline-rich phosphoprotein 1/2; PRP's act as highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth. (166 aa)
	PRB1	Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1. (198 aa)
	PRB3	Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum. (351 aa)
	PRH1	Proline rich protein HaeIII subfamily 1. (187 aa)
	ENSP00000481571	Uncharacterized protein. (122 aa)
	PRR4	Proline-rich protein 4; Proline rich 4. (134 aa)
	PRB4	Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4. (247 aa)
	PRB2	Basic salivary proline-rich protein 2; Proline rich protein BstNI subfamily 2. (416 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PRB1	PRB2	ENSP00000420826	ENSP00000374013	Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1.	Basic salivary proline-rich protein 2; Proline rich protein BstNI subfamily 2.	0.909
PRB1	PRB3	ENSP00000420826	ENSP00000442626	Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1.	Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum.	0.817
PRB1	PRB4	ENSP00000420826	ENSP00000279575	Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1.	Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4.	0.999
PRB1	PRH2	ENSP00000420826	ENSP00000379682	Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1.	Salivary acidic proline-rich phosphoprotein 1/2; PRP's act as highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth.	0.890
PRB1	PRR4	ENSP00000420826	ENSP00000228811	Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1.	Proline-rich protein 4; Proline rich 4.	0.623
PRB2	PRB1	ENSP00000374013	ENSP00000420826	Basic salivary proline-rich protein 2; Proline rich protein BstNI subfamily 2.	Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1.	0.909
PRB2	PRH2	ENSP00000374013	ENSP00000379682	Basic salivary proline-rich protein 2; Proline rich protein BstNI subfamily 2.	Salivary acidic proline-rich phosphoprotein 1/2; PRP's act as highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth.	0.864
PRB3	PRB1	ENSP00000442626	ENSP00000420826	Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum.	Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1.	0.817
PRB3	PRB4	ENSP00000442626	ENSP00000279575	Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum.	Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4.	0.999
PRB3	PRH1	ENSP00000442626	ENSP00000479168	Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum.	Proline rich protein HaeIII subfamily 1.	0.466
PRB3	PRR4	ENSP00000442626	ENSP00000228811	Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum.	Proline-rich protein 4; Proline rich 4.	0.480
PRB4	PRB1	ENSP00000279575	ENSP00000420826	Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4.	Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1.	0.999
PRB4	PRB3	ENSP00000279575	ENSP00000442626	Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4.	Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum.	0.999
PRB4	PRH1	ENSP00000279575	ENSP00000479168	Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4.	Proline rich protein HaeIII subfamily 1.	0.924
PRB4	PRH2	ENSP00000279575	ENSP00000379682	Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4.	Salivary acidic proline-rich phosphoprotein 1/2; PRP's act as highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth.	0.916
PRB4	PRR4	ENSP00000279575	ENSP00000228811	Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4.	Proline-rich protein 4; Proline rich 4.	0.437
PRH1	PRB3	ENSP00000479168	ENSP00000442626	Proline rich protein HaeIII subfamily 1.	Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum.	0.466
PRH1	PRB4	ENSP00000479168	ENSP00000279575	Proline rich protein HaeIII subfamily 1.	Basic salivary proline-rich protein 4; Proline rich protein BstNI subfamily 4.	0.924
PRH1	PRH2	ENSP00000479168	ENSP00000379682	Proline rich protein HaeIII subfamily 1.	Salivary acidic proline-rich phosphoprotein 1/2; PRP's act as highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth.	0.900
PRH2	PRB1	ENSP00000379682	ENSP00000420826	Salivary acidic proline-rich phosphoprotein 1/2; PRP's act as highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth.	Basic salivary proline-rich protein 1; Proline rich protein BstNI subfamily 1.	0.890