STRINGSTRING
ERBB3 ERBB3 EGFR EGFR GAB1 GAB1 NRG2 NRG2 NRG1 NRG1 PIK3R1 PIK3R1 EREG EREG NRG3 NRG3 ERBB4 ERBB4 PIK3CA PIK3CA GRB2 GRB2 HBEGF HBEGF BTC BTC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERBB3Erb-b2 receptor tyrosine kinase 3. (1338 aa)
EGFRReceptor protein-tyrosine kinase. (1141 aa)
GAB1GRB2 associated binding protein 1. (701 aa)
NRG2Neuregulin 2. (868 aa)
NRG1Neuregulin 1. (713 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
EREGEpiregulin. (160 aa)
NRG3Neuregulin 3. (720 aa)
ERBB4Receptor protein-tyrosine kinase. (1324 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
GRB2Growth factor receptor bound protein 2. (250 aa)
HBEGFHeparin binding EGF like growth factor. (263 aa)
BTCBetacellulin. (187 aa)
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.