STRINGSTRING
GLS2 GLS2 SCO2 SCO2 YWHAZ YWHAZ LRPPRC LRPPRC CYCS CYCS COX18 COX18 RRAGD RRAGD RRAGC RRAGC PRKAG2 PRKAG2 PRKAG3 PRKAG3 AKT2 AKT2 RPTOR RPTOR LAMTOR1 LAMTOR1 GSR GSR SLC38A9 SLC38A9 GPI GPI PRKAG1 PRKAG1 GLS GLS YWHAB YWHAB SFN SFN TACO1 TACO1 F1PYD3_CANLF F1PYD3_CANLF PRDX5 PRDX5 LAMTOR4 LAMTOR4 AKT3 AKT3 GPX2 GPX2 RRAGB RRAGB COX16 COX16 MTOR MTOR COX11 COX11 AKT1 AKT1 PRKAA2 PRKAA2 G6PD G6PD TSC1 TSC1 COX4I1 COX4I1 COX1 COX1 COX2 COX2 MLST8 MLST8 PRDX2 PRDX2 YWHAQ YWHAQ LOC612644 LOC612644 YWHAG YWHAG COX7A2L COX7A2L SCO1 SCO1 COX14 COX14 TIGAR TIGAR J9NWJ5_CANLF J9NWJ5_CANLF J9NWS5_CANLF J9NWS5_CANLF TSC2 TSC2 LAMTOR3 LAMTOR3 J9P0E1_CANLF J9P0E1_CANLF J9P7L3_CANLF J9P7L3_CANLF SESN2 SESN2 DDIT4 DDIT4 ENSCAFP00000043909 ENSCAFP00000043909 LAMTOR5 LAMTOR5 LOC100684983 LOC100684983 NDUFA4 NDUFA4 PRKAB1 PRKAB1 RHEB RHEB ENSCAFP00000050726 ENSCAFP00000050726 PRKAA1 PRKAA1 SESN1 SESN1 YWHAE YWHAE YWHAH YWHAH LAMTOR2 LAMTOR2 ENSCAFP00000058407 ENSCAFP00000058407 LOC609990 LOC609990 SURF1 SURF1 ENSCAFP00000060857 ENSCAFP00000060857 SESN3 SESN3 COX20 COX20 RRAGA RRAGA TXNRD1 TXNRD1 ENSCAFP00000065700 ENSCAFP00000065700
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLS2Glutaminase 2. (603 aa)
SCO2SCO cytochrome c oxidase assembly protein 2. (390 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (236 aa)
LRPPRCLeucine rich pentatricopeptide repeat containing. (1393 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
COX18Cytochrome c oxidase assembly factor COX18. (445 aa)
RRAGDRas related GTP binding D. (385 aa)
RRAGCRas related GTP binding C. (539 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (545 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (597 aa)
AKT2AKT serine/threonine kinase 2. (557 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (521 aa)
SLC38A9Solute carrier family 38 member 9. (561 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (560 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa)
GLSGlutaminase. (754 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
TACO1Translational activator of cytochrome c oxidase I. (298 aa)
F1PYD3_CANLFCytochrome c oxidase subunit 6A, mitochondrial. (110 aa)
PRDX5Redoxin domain-containing protein. (174 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (99 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (189 aa)
RRAGBRas related GTP binding B. (374 aa)
COX16Cytochrome c oxidase assembly factor COX16. (106 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2647 aa)
COX11Cytochrome c oxidase copper chaperone COX11. (305 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PRKAA2Non-specific serine/threonine protein kinase. (532 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (624 aa)
TSC1TSC complex subunit 1. (1169 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (169 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
PRDX2Peroxiredoxin 2. (198 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa)
LOC612644Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (245 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (114 aa)
SCO1SCO cytochrome c oxidase assembly protein 1. (304 aa)
COX14Cytochrome c oxidase assembly factor COX14. (57 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (318 aa)
J9NWJ5_CANLFThioredoxin; Belongs to the thioredoxin family. (106 aa)
J9NWS5_CANLFUncharacterized protein; Belongs to the cytochrome c oxidase subunit 6A family. (92 aa)
TSC2TSC complex subunit 2. (1783 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
J9P0E1_CANLFUncharacterized protein. (69 aa)
J9P7L3_CANLFThioredoxin domain-containing protein. (199 aa)
SESN2Sestrin 2. (485 aa)
DDIT4DNA damage inducible transcript 4. (606 aa)
ENSCAFP00000043909Uncharacterized protein. (79 aa)
LAMTOR5Uncharacterized protein. (79 aa)
LOC100684983Uncharacterized protein. (80 aa)
NDUFA4Uncharacterized protein. (82 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (275 aa)
RHEBRas homolog, mTORC1 binding. (232 aa)
ENSCAFP00000050726Uncharacterized protein. (129 aa)
PRKAA1Non-specific serine/threonine protein kinase. (573 aa)
SESN1Sestrin 1. (658 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (314 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (266 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (149 aa)
ENSCAFP00000058407Uncharacterized protein. (169 aa)
LOC609990Uncharacterized protein. (63 aa)
SURF1SURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family. (352 aa)
ENSCAFP00000060857Uncharacterized protein; Belongs to the cytochrome c oxidase subunit 6A family. (85 aa)
SESN3Sestrin 3. (573 aa)
COX20Cytochrome c oxidase assembly factor COX20. (163 aa)
RRAGARas related GTP binding A. (595 aa)
TXNRD1Thioredoxin reductase 1; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (744 aa)
ENSCAFP00000065700CHCH domain-containing protein. (95 aa)
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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