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PSME4 PSME4 PSMB2 PSMB2 PSMD5 PSMD5 PSMC2 PSMC2 PSMC4 PSMC4 PSMF1 PSMF1 PSMD9 PSMD9 PSMC3 PSMC3 PSMD14 PSMD14 CHEK1 CHEK1 PSMB5 PSMB5 PSME1 PSME1 PSMA7 PSMA7 PSMD4 PSMD4 PSMD2 PSMD2 PSMB4 PSMB4 PSMC5 PSMC5 CDC25A CDC25A PSMA6 PSMA6 UBA52 UBA52 PSMB6 PSMB6 PSMD3 PSMD3 PSMB3 PSMB3 PSMC1 PSMC1 PSMA8 PSMA8 PSMD11 PSMD11 PSMA5 PSMA5 PSMB10 PSMB10 PSMB1 PSMB1 RPS27A RPS27A PSMD10 PSMD10 PSMD13 PSMD13 PSMD12 PSMD12 PSMB9 PSMB9 LOC100687259 LOC100687259 J9P2T7_CANLF J9P2T7_CANLF PSMD7 PSMD7 PSMA3 PSMA3 ENSCAFP00000047134 ENSCAFP00000047134 PSMA4 PSMA4 PSMC6 PSMC6 ENSCAFP00000050780 ENSCAFP00000050780 PSMB7 PSMB7 PSMA2 PSMA2 PSME2 PSME2 PSMD1 PSMD1 PSMA1 PSMA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSME4Proteasome activator subunit 4. (1762 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD5Uncharacterized protein. (500 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMD9Proteasome 26S subunit, non-ATPase 9. (223 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (308 aa)
CHEK1Checkpoint kinase 1. (454 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSMA7Proteasome endopeptidase complex. (178 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (377 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
CDC25ACell division cycle 25A. (524 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
UBA52Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMB10Proteasome subunit beta. (272 aa)
PSMB1Proteasome subunit beta. (241 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMB9Proteasome subunit beta. (209 aa)
LOC100687259AAA domain-containing protein; Belongs to the AAA ATPase family. (365 aa)
J9P2T7_CANLFUncharacterized protein. (461 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA3Proteasome endopeptidase complex. (257 aa)
ENSCAFP00000047134Proteasome endopeptidase complex. (216 aa)
PSMA4Proteasome subunit alpha 4. (290 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
ENSCAFP00000050780Ubiquitin-like domain-containing protein. (151 aa)
PSMB7Proteasome subunit beta. (315 aa)
PSMA2Proteasome subunit alpha type. (295 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMA1Proteasome subunit alpha type. (267 aa)
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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