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| | ARHGEF25 | Rho guanine nucleotide exchange factor 25. (619 aa) |
| | SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1. (1086 aa) |
| | NOX3 | Predicted NADPH oxidase-3. (567 aa) |
| | TAGAP | T cell activation RhoGTPase activating protein. (723 aa) |
| | DEF6 | DEF6 guanine nucleotide exchange factor. (631 aa) |
| | CDC42EP1 | CDC42 effector protein 1. (326 aa) |
| | NCF4 | Neutrophil cytosolic factor 4. (339 aa) |
| | ARHGAP39 | Rho GTPase activating protein 39. (1050 aa) |
| | LOC475497 | Uncharacterized protein; Belongs to the synaptobrevin family. (182 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | ARHGEF5 | Rho guanine nucleotide exchange factor 5. (1604 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (820 aa) |
| | WASF1 | WASP family member 1. (559 aa) |
| | ARHGAP12 | Rho GTPase activating protein 12. (897 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | ABI1 | Abl interactor 1. (508 aa) |
| | PAK3 | P21 (RAC1) activated kinase 3. (583 aa) |
| | BRK1 | BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa) |
| | ARHGAP15 | Rho GTPase activating protein 15. (471 aa) |
| | SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3. (1099 aa) |
| | FARP1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1041 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) |
| | ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1388 aa) |
| | PAK5 | Non-specific serine/threonine protein kinase. (719 aa) |
| | LAMTOR1 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa) |
| | ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3. (1542 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1353 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1133 aa) |
| | DLC1 | Rho GTPase-activating protein 7; Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality (By similarity). (1526 aa) |
| | WASF3 | WASP family member 3. (502 aa) |
| | SPATA13 | Uncharacterized protein. (1331 aa) |
| | KIAA0355 | KIAA0355. (1041 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (725 aa) |
| | PREX2 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1605 aa) |
| | RBM39 | RNA binding motif protein 39. (530 aa) |
| | PAK6 | Non-specific serine/threonine protein kinase. (681 aa) |
| | DOCK5 | Dedicator of cytokinesis 5; Belongs to the DOCK family. (1869 aa) |
| | ARHGAP1 | Cdc42 GTPase-activating protein. (439 aa) |
| | AMIGO2 | Adhesion molecule with Ig like domain 2. (521 aa) |
| | TRIO | Trio Rho guanine nucleotide exchange factor. (3053 aa) |
| | NISCH | Nischarin. (1537 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1213 aa) |
| | TAOK3 | TAO kinase 3. (898 aa) |
| | CIT | Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa) |
| | DOCK3 | Dedicator of cytokinesis 3; Belongs to the DOCK family. (2030 aa) |
| | GIT2 | GIT ArfGAP 2. (759 aa) |
| | GNA13 | G protein subunit alpha 13. (282 aa) |
| | SNAP23 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa) |
| | NGEF | Neuronal guanine nucleotide exchange factor. (675 aa) |
| | WASF2 | WASP family member 2. (498 aa) |
| | KALRN | Kalirin RhoGEF kinase. (2987 aa) |
| | ALS2 | Alsin Rho guanine nucleotide exchange factor ALS2. (1656 aa) |
| | ARHGAP30 | Rho GTPase activating protein 30. (1096 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1657 aa) |
| | ARHGDIB | Rho GDP dissociation inhibitor beta. (200 aa) |
| | DOCK1 | Dedicator of cytokinesis 1; Belongs to the DOCK family. (1896 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1375 aa) |
| | NCKAP1 | NCK associated protein 1. (1102 aa) |
| | PIK3R2 | Uncharacterized protein. (726 aa) |
| | KTN1 | Kinectin 1. (1473 aa) |
| | PLD2 | Phospholipase. (837 aa) |
| | ARHGEF19 | Rho guanine nucleotide exchange factor 19. (704 aa) |
| | EPHA2 | EPH receptor A2. (1121 aa) |
| | LBR | Lamin B receptor. (618 aa) |
| | PKN1 | Protein kinase N1. (1145 aa) |
| | OPHN1 | Oligophrenin 1. (802 aa) |
| | DOCK2 | Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa) |
| | ARHGAP17 | Rho GTPase activating protein 17. (918 aa) |
| | CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1289 aa) |
| | NOX1 | NADPH oxidase 1. (564 aa) |
| | ARHGAP44 | Rho GTPase activating protein 44. (813 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (845 aa) |
| | GIT1 | GIT ArfGAP 1. (770 aa) |
| | MCF2 | MCF.2 cell line derived transforming sequence. (1058 aa) |
| | NOXO1 | NADPH oxidase organizer 1. (476 aa) |
| | ARHGAP29 | Rho GTPase activating protein 29. (1269 aa) |
| | SYDE2 | Synapse defective Rho GTPase homolog 2. (1096 aa) |
| | VANGL1 | Vang-like protein. (524 aa) |
| | CFD | Rho GTPase activating protein 45. (1130 aa) |
| | CHN2 | Chimaerin; GTPase-activating protein for p21-rac. (468 aa) |
| | PLEKHG6 | Pleckstrin homology and RhoGEF domain containing G6. (800 aa) |
| | DOCK6 | Dedicator of cytokinesis 6; Belongs to the DOCK family. (2101 aa) |
| | PREX1 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1585 aa) |
| | DIAPH3 | Diaphanous related formin 3. (1191 aa) |
| | ARHGAP35 | Rho GTPase-activating protein 35; Rho GTPase-activating protein (GAP). Binds several acidic phospholipids which inhibits the Rho GAP activity to promote the Rac GAP activity. This binding is inhibited by phosphorylation by PRKCA (By similarity). Involved in cell differentiation as well as cell adhesion and migration, plays an important role in retinal tissue morphogenesis, neural tube fusion, midline fusion of the cerebral hemispheres and mammary gland branching morphogenesis (By similarity). Transduces signals from p21-ras to the nucleus, acting via the ras GTPase- activating protein [...] (1516 aa) |
| | DOCK7 | Dedicator of cytokinesis 7; Belongs to the DOCK family. (2030 aa) |
| | PLEKHG2 | Pleckstrin homology and RhoGEF domain containing G2. (1388 aa) |
| | ARHGAP33 | Rho GTPase activating protein 33. (1082 aa) |
| | RASGRF2 | Ras protein specific guanine nucleotide releasing factor 2. (1215 aa) |
| | ARHGAP10 | Rho GTPase activating protein 10. (786 aa) |
| | FMNL1 | Formin like 1. (1121 aa) |
| | PLD1 | Phospholipase. (1030 aa) |
| | GMIP | GEM interacting protein. (1076 aa) |
| | ARHGAP23 | Rho GTPase activating protein 23. (1145 aa) |
| | ARHGAP31 | Rho GTPase activating protein 31. (1466 aa) |
| | PARD6A | Par-6 family cell polarity regulator alpha. (514 aa) |
| | EMD | Emerin. (260 aa) |
| | ARHGAP22 | Rho GTPase activating protein 22. (680 aa) |
| | RACGAP1 | Rac GTPase activating protein 1. (632 aa) |
| | VRK2 | VRK serine/threonine kinase 2. (490 aa) |
| | FERMT2 | Fermitin family member 2. (637 aa) |
| | SWAP70 | Switching B cell complex subunit SWAP70. (590 aa) |
| | ARHGAP24 | Rho GTPase activating protein 24. (753 aa) |
| | RAB7A | Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth- factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism (By simi [...] (228 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (552 aa) |
| | FARP2 | FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1052 aa) |
| | ABR | ABR activator of RhoGEF and GTPase. (871 aa) |
| | DOCK9 | Dedicator of cytokinesis 9; Belongs to the DOCK family. (2152 aa) |
| | MCAM | Melanoma cell adhesion molecule. (723 aa) |
| | CHN1 | Chimaerin; GTPase-activating protein for p21-rac. (454 aa) |
| | FAM13B | Family with sequence similarity 13 member B. (971 aa) |
| | PLEKHG3 | Pleckstrin homology and RhoGEF domain containing G3. (1395 aa) |
| | DOCK11 | Dedicator of cytokinesis 11; Belongs to the DOCK family. (2103 aa) |
| | ARHGEF39 | Rho guanine nucleotide exchange factor 39. (413 aa) |
| | ARHGAP5 | Rho GTPase activating protein 5. (1503 aa) |
| | RALBP1 | RalA binding protein 1. (669 aa) |
| | NHS | NHS actin remodeling regulator. (1628 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | ARHGEF15 | Rho guanine nucleotide exchange factor 15. (885 aa) |
| | ECT2 | Epithelial cell transforming 2. (943 aa) |
| | FGD5 | FYVE, RhoGEF and PH domain containing 5. (1501 aa) |
| | FAM13A | Family with sequence similarity 13 member A. (1058 aa) |
| | SLC1A5 | Amino acid transporter. (541 aa) |
| | ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2. (1550 aa) |
| | BAIAP2L1 | BAI1 associated protein 2 like 1. (530 aa) |
| | MCF2L | MCF.2 cell line derived transforming sequence like. (1188 aa) |
| | CDC42BPA | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1845 aa) |
| | ELOVL7 | DEP domain containing 1B. (725 aa) |
| | MPP7 | Membrane palmitoylated protein 7; Belongs to the MAGUK family. (618 aa) |
| | ABI2 | Abl interactor 2. (582 aa) |
| | DOCK10 | Dedicator of cytokinesis 10; Belongs to the DOCK family. (2206 aa) |
| | ARHGEF11 | Rho guanine nucleotide exchange factor 11. (1585 aa) |
| | CYBA | Cytochrome b-245 alpha chain. (336 aa) |
| | ARHGAP32 | Rho GTPase activating protein 32. (2113 aa) |
| | NCF2 | Neutrophil cytosolic factor 2. (535 aa) |
| | SRGAP2 | Uncharacterized protein. (1078 aa) |
| | ARHGAP42 | Rho GTPase activating protein 42. (837 aa) |
| | MYO9B | Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2271 aa) |
| | ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor 6. (740 aa) |
| | PKN2 | Protein kinase N2. (1013 aa) |
| | ARHGAP26 | Rho GTPase activating protein 26. (936 aa) |
| | ARHGAP20 | Rho GTPase activating protein 20. (1266 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (656 aa) |
| | CDC42-2 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (191 aa) |
| | IQGAP2 | IQ motif containing GTPase activating protein 2. (1621 aa) |
| | DOCK8 | Dedicator of cytokinesis 8; Belongs to the DOCK family. (2093 aa) |
| | SH3BP1 | SH3 domain binding protein 1. (808 aa) |
| | ARHGAP21 | Rho GTPase activating protein 21. (1940 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1601 aa) |
| | BAIAP2 | BAI1 associated protein 2. (630 aa) |
| | ARHGEF7 | Rho guanine nucleotide exchange factor 7. (807 aa) |
| | ESYT1 | Extended synaptotagmin 1. (1049 aa) |
| | VAV2 | Vav guanine nucleotide exchange factor 2. (821 aa) |
| | BCR | BCR activator of RhoGEF and GTPase. (1262 aa) |
| | PLEKHG1 | Pleckstrin homology and RhoGEF domain containing G1. (1478 aa) |
| | ERBIN | Erbb2 interacting protein. (1460 aa) |
| | VAMP3 | Vesicle associated membrane protein 3. (145 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (859 aa) |
| | DOCK4 | Dedicator of cytokinesis 4; Belongs to the DOCK family. (1974 aa) |
| | ARHGAP4 | Rho GTPase activating protein 4. (1125 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (718 aa) |
| | ENSCAFP00000064660 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. (153 aa) |
| | ARHGDIA | Rho GDP dissociation inhibitor alpha. (281 aa) |
| | ABL2 | Tyrosine-protein kinase. (1148 aa) |
| | IQGAP3 | IQ motif containing GTPase activating protein 3. (1733 aa) |
| | TIAM2 | T cell lymphoma invasion and metastasis 2. (1539 aa) |
