STRINGSTRING
SOCS2 SOCS2 SLA2 SLA2 SH2B3 SH2B3 UBA52 UBA52 CSK CSK RPS27A RPS27A PTPRJ PTPRJ SOCS6 SOCS6 CBL CBL SLA SLA ENSCAFP00000050780 ENSCAFP00000050780 FLT3 FLT3 FLT3LG FLT3LG ABL2 ABL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOCS2Suppressor of cytokine signaling 2. (299 aa)
SLA2Src like adaptor 2. (276 aa)
SH2B3SH2B adaptor protein 3. (586 aa)
UBA52Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
CSKTyrosine-protein kinase. (450 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1229 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
CBLCbl proto-oncogene. (895 aa)
SLASrc like adaptor. (315 aa)
ENSCAFP00000050780Ubiquitin-like domain-containing protein. (151 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1029 aa)
FLT3LGFms related tyrosine kinase 3 ligand. (498 aa)
ABL2Tyrosine-protein kinase. (1148 aa)
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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