(5 nodes) Mixed, incl. Krueppel-associated box, and TMC domain network (Canis lupus familiaris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TMC6	Transmembrane channel-like protein. (766 aa)
	LRFN4	Leucine rich repeat and fibronectin type III domain containing 4. (636 aa)
	DUSP27	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (1126 aa)
	ZNF331	Zinc finger protein 331; May be involved in transcriptional regulation. May play a role in spermatogenesis (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. (497 aa)
	RAVER1	Uncharacterized protein. (758 aa)

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP27	LRFN4	ENSCAFP00000022900	ENSCAFP00000017440	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Leucine rich repeat and fibronectin type III domain containing 4.	0.813
DUSP27	RAVER1	ENSCAFP00000022900	ENSCAFP00000059915	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Uncharacterized protein.	0.785
DUSP27	TMC6	ENSCAFP00000022900	ENSCAFP00000007873	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Transmembrane channel-like protein.	0.725
DUSP27	ZNF331	ENSCAFP00000022900	ENSCAFP00000040347	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Zinc finger protein 331; May be involved in transcriptional regulation. May play a role in spermatogenesis (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family.	0.656
LRFN4	DUSP27	ENSCAFP00000017440	ENSCAFP00000022900	Leucine rich repeat and fibronectin type III domain containing 4.	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.813
LRFN4	RAVER1	ENSCAFP00000017440	ENSCAFP00000059915	Leucine rich repeat and fibronectin type III domain containing 4.	Uncharacterized protein.	0.785
LRFN4	TMC6	ENSCAFP00000017440	ENSCAFP00000007873	Leucine rich repeat and fibronectin type III domain containing 4.	Transmembrane channel-like protein.	0.727
LRFN4	ZNF331	ENSCAFP00000017440	ENSCAFP00000040347	Leucine rich repeat and fibronectin type III domain containing 4.	Zinc finger protein 331; May be involved in transcriptional regulation. May play a role in spermatogenesis (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family.	0.727
RAVER1	DUSP27	ENSCAFP00000059915	ENSCAFP00000022900	Uncharacterized protein.	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.785
RAVER1	LRFN4	ENSCAFP00000059915	ENSCAFP00000017440	Uncharacterized protein.	Leucine rich repeat and fibronectin type III domain containing 4.	0.785
RAVER1	TMC6	ENSCAFP00000059915	ENSCAFP00000007873	Uncharacterized protein.	Transmembrane channel-like protein.	0.680
RAVER1	ZNF331	ENSCAFP00000059915	ENSCAFP00000040347	Uncharacterized protein.	Zinc finger protein 331; May be involved in transcriptional regulation. May play a role in spermatogenesis (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family.	0.627
TMC6	DUSP27	ENSCAFP00000007873	ENSCAFP00000022900	Transmembrane channel-like protein.	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.725
TMC6	LRFN4	ENSCAFP00000007873	ENSCAFP00000017440	Transmembrane channel-like protein.	Leucine rich repeat and fibronectin type III domain containing 4.	0.727
TMC6	RAVER1	ENSCAFP00000007873	ENSCAFP00000059915	Transmembrane channel-like protein.	Uncharacterized protein.	0.680
TMC6	ZNF331	ENSCAFP00000007873	ENSCAFP00000040347	Transmembrane channel-like protein.	Zinc finger protein 331; May be involved in transcriptional regulation. May play a role in spermatogenesis (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family.	0.638
ZNF331	DUSP27	ENSCAFP00000040347	ENSCAFP00000022900	Zinc finger protein 331; May be involved in transcriptional regulation. May play a role in spermatogenesis (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family.	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.656
ZNF331	LRFN4	ENSCAFP00000040347	ENSCAFP00000017440	Zinc finger protein 331; May be involved in transcriptional regulation. May play a role in spermatogenesis (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family.	Leucine rich repeat and fibronectin type III domain containing 4.	0.727
ZNF331	RAVER1	ENSCAFP00000040347	ENSCAFP00000059915	Zinc finger protein 331; May be involved in transcriptional regulation. May play a role in spermatogenesis (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family.	Uncharacterized protein.	0.627
ZNF331	TMC6	ENSCAFP00000040347	ENSCAFP00000007873	Zinc finger protein 331; May be involved in transcriptional regulation. May play a role in spermatogenesis (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family.	Transmembrane channel-like protein.	0.638