5 items (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	LIG4	DNA ligase. (911 aa)
	PRKDC	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act [...] (4067 aa)
	XRCC5	X-ray repair cross complementing 5. (829 aa)
	NHEJ1	Non-homologous end joining factor 1. (299 aa)
	XRCC6	X-ray repair cross complementing 6. (612 aa)

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LIG4	NHEJ1	ENSCAFP00000009027	ENSCAFP00000039487	DNA ligase.	Non-homologous end joining factor 1.	0.987
LIG4	PRKDC	ENSCAFP00000009027	ENSCAFP00000009842	DNA ligase.	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act [...]	0.963
LIG4	XRCC5	ENSCAFP00000009027	ENSCAFP00000038467	DNA ligase.	X-ray repair cross complementing 5.	0.985
LIG4	XRCC6	ENSCAFP00000009027	ENSCAFP00000058107	DNA ligase.	X-ray repair cross complementing 6.	0.989
NHEJ1	LIG4	ENSCAFP00000039487	ENSCAFP00000009027	Non-homologous end joining factor 1.	DNA ligase.	0.987
NHEJ1	PRKDC	ENSCAFP00000039487	ENSCAFP00000009842	Non-homologous end joining factor 1.	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act [...]	0.971
NHEJ1	XRCC5	ENSCAFP00000039487	ENSCAFP00000038467	Non-homologous end joining factor 1.	X-ray repair cross complementing 5.	0.976
NHEJ1	XRCC6	ENSCAFP00000039487	ENSCAFP00000058107	Non-homologous end joining factor 1.	X-ray repair cross complementing 6.	0.928
PRKDC	LIG4	ENSCAFP00000009842	ENSCAFP00000009027	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act [...]	DNA ligase.	0.963
PRKDC	NHEJ1	ENSCAFP00000009842	ENSCAFP00000039487	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act [...]	Non-homologous end joining factor 1.	0.971
PRKDC	XRCC5	ENSCAFP00000009842	ENSCAFP00000038467	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act [...]	X-ray repair cross complementing 5.	0.993
PRKDC	XRCC6	ENSCAFP00000009842	ENSCAFP00000058107	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act [...]	X-ray repair cross complementing 6.	0.990
XRCC5	LIG4	ENSCAFP00000038467	ENSCAFP00000009027	X-ray repair cross complementing 5.	DNA ligase.	0.985
XRCC5	NHEJ1	ENSCAFP00000038467	ENSCAFP00000039487	X-ray repair cross complementing 5.	Non-homologous end joining factor 1.	0.976
XRCC5	PRKDC	ENSCAFP00000038467	ENSCAFP00000009842	X-ray repair cross complementing 5.	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act [...]	0.993
XRCC5	XRCC6	ENSCAFP00000038467	ENSCAFP00000058107	X-ray repair cross complementing 5.	X-ray repair cross complementing 6.	0.999
XRCC6	LIG4	ENSCAFP00000058107	ENSCAFP00000009027	X-ray repair cross complementing 6.	DNA ligase.	0.989
XRCC6	NHEJ1	ENSCAFP00000058107	ENSCAFP00000039487	X-ray repair cross complementing 6.	Non-homologous end joining factor 1.	0.928
XRCC6	PRKDC	ENSCAFP00000058107	ENSCAFP00000009842	X-ray repair cross complementing 6.	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act [...]	0.990
XRCC6	XRCC5	ENSCAFP00000058107	ENSCAFP00000038467	X-ray repair cross complementing 6.	X-ray repair cross complementing 5.	0.999