(45 nodes) Intramolecular oxidoreductase activity network (Canis lupus familiaris)

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	TXNDC5	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (323 aa)
	P4HB	Protein disulfide-isomerase. (533 aa)
	PDIA6	Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (462 aa)
	EBPL	EBP like. (381 aa)
	LOC475755	Uncharacterized protein. (239 aa)
	HPGDS	Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa)
	HYI	Hydroxypyruvate isomerase (putative). (362 aa)
	ENSCAFP00000060389	Nudix hydrolase domain-containing protein. (178 aa)
	QSOX1	Sulfhydryl oxidase. (713 aa)
	PDIA2	Protein disulfide isomerase family A member 2. (581 aa)
	PDIA4	Protein disulfide isomerase family A member 4; Belongs to the protein disulfide isomerase family. (715 aa)
	DDT	D-dopachrome tautomerase like. (118 aa)
	ENSCAFP00000053629	Uncharacterized protein. (122 aa)
	GNPDA2	Glucosamine-6-phosphate deaminase 2. (608 aa)
	GNPDA1	Glucosamine-6-phosphate isomerase. (303 aa)
	ENSCAFP00000050733	Glucose-6-phosphate isomerase; Belongs to the GPI family. (548 aa)
	PTGDS	Prostaglandin-H2 D-isomerase; Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possib [...] (350 aa)
	ECI1	Enoyl-CoA delta isomerase 1. (243 aa)
	PTGES	Prostaglandin E synthase; Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). (153 aa)
	J9P1D3_CANLF	Thioredoxin domain-containing protein. (72 aa)
	RPIA	Uncharacterized protein. (311 aa)
	E2QYH5_CANLF	EXPERA domain-containing protein. (228 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (919 aa)
	PTGES2	Prostaglandin E synthase 2. (372 aa)
	QSOX2	Sulfhydryl oxidase. (699 aa)
	PDILT	Protein disulfide isomerase like, testis expressed. (580 aa)
	MPI	Mannose-6-phosphate isomerase. (567 aa)
	MRI1	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (368 aa)
	TXNDC16	Thioredoxin domain containing 16. (796 aa)
	TPI1	Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (286 aa)
	ECHS1	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
	PDIA3	Protein disulfide-isomerase. (505 aa)
	ERP27	Endoplasmic reticulum protein 27. (273 aa)
	PDIA5	Protein disulfide isomerase family A member 5. (519 aa)
	PTGIS	Prostaglandin I2 synthase; Belongs to the cytochrome P450 family. (475 aa)
	HSD3B2	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids (By similarity). (373 aa)
	ECI2	Enoyl-CoA delta isomerase 2. (373 aa)
	ENOPH1	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (366 aa)
	GPI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (560 aa)
	LGALS4	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (352 aa)
	DCT	Uncharacterized protein. (548 aa)
	TBXAS1	Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (534 aa)
	ERP44	Endoplasmic reticulum protein 44. (323 aa)
	CRELD2	Cysteine rich with EGF like domains 2. (391 aa)
	TMX3	Thioredoxin related transmembrane protein 3. (453 aa)

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRELD2	EBPL	ENSCAFP00000001013	ENSCAFP00000063957	Cysteine rich with EGF like domains 2.	EBP like.	0.549
CRELD2	J9P1D3_CANLF	ENSCAFP00000001013	ENSCAFP00000039357	Cysteine rich with EGF like domains 2.	Thioredoxin domain-containing protein.	0.489
CRELD2	PDIA3	ENSCAFP00000001013	ENSCAFP00000019653	Cysteine rich with EGF like domains 2.	Protein disulfide-isomerase.	0.489
CRELD2	PDIA4	ENSCAFP00000001013	ENSCAFP00000056407	Cysteine rich with EGF like domains 2.	Protein disulfide isomerase family A member 4; Belongs to the protein disulfide isomerase family.	0.839
CRELD2	PDIA5	ENSCAFP00000001013	ENSCAFP00000017744	Cysteine rich with EGF like domains 2.	Protein disulfide isomerase family A member 5.	0.558
CRELD2	PDIA6	ENSCAFP00000001013	ENSCAFP00000064087	Cysteine rich with EGF like domains 2.	Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.	0.717
CRELD2	TMX3	ENSCAFP00000001013	ENSCAFP00000000054	Cysteine rich with EGF like domains 2.	Thioredoxin related transmembrane protein 3.	0.405
E2QYH5_CANLF	ENSCAFP00000060389	ENSCAFP00000035357	ENSCAFP00000060389	EXPERA domain-containing protein.	Nudix hydrolase domain-containing protein.	0.610
EBPL	CRELD2	ENSCAFP00000063957	ENSCAFP00000001013	EBP like.	Cysteine rich with EGF like domains 2.	0.549
ECHS1	ECI1	ENSCAFP00000019760	ENSCAFP00000041497	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA delta isomerase 1.	0.765
ECHS1	ECI2	ENSCAFP00000019760	ENSCAFP00000013857	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA delta isomerase 2.	0.486
ECHS1	LGALS4	ENSCAFP00000019760	ENSCAFP00000008457	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.649
ECI1	ECHS1	ENSCAFP00000041497	ENSCAFP00000019760	Enoyl-CoA delta isomerase 1.	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.765
ECI1	ECI2	ENSCAFP00000041497	ENSCAFP00000013857	Enoyl-CoA delta isomerase 1.	Enoyl-CoA delta isomerase 2.	0.984
ECI1	LGALS4	ENSCAFP00000041497	ENSCAFP00000008457	Enoyl-CoA delta isomerase 1.	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.855
ECI2	ECHS1	ENSCAFP00000013857	ENSCAFP00000019760	Enoyl-CoA delta isomerase 2.	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.486
ECI2	ECI1	ENSCAFP00000013857	ENSCAFP00000041497	Enoyl-CoA delta isomerase 2.	Enoyl-CoA delta isomerase 1.	0.984
ECI2	LGALS4	ENSCAFP00000013857	ENSCAFP00000008457	Enoyl-CoA delta isomerase 2.	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.821
ENOPH1	MRI1	ENSCAFP00000013183	ENSCAFP00000024457	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	0.909
ENSCAFP00000050733	GNPDA1	ENSCAFP00000050733	ENSCAFP00000053266	Glucose-6-phosphate isomerase; Belongs to the GPI family.	Glucosamine-6-phosphate isomerase.	0.477