STRINGSTRING
SNRPC-4 SNRPC-4 LSM3-4 LSM3-4 LRMDA LRMDA LSM3-3 LSM3-3 LSM3-2 LSM3-2 MEPCE MEPCE SNRPC-3 SNRPC-3 J9P8E9_CANLF J9P8E9_CANLF LOC100686524 LOC100686524 RBM41 RBM41 SNRPC SNRPC PRPF31 PRPF31 PRPF4 PRPF4 LSM10 LSM10 SNRNP70 SNRNP70 TOE1 TOE1 SNRPA SNRPA LRTOMT LRTOMT KMT5A KMT5A CCNT1 CCNT1 SNRPA1 SNRPA1 ISG20 ISG20 LARP7 LARP7 DDX21 DDX21 GEMIN5 GEMIN5 J9NXJ9_CANLF J9NXJ9_CANLF CDK9 CDK9 SNRPC-2 SNRPC-2 SNRPB2 SNRPB2 HEXIM1 HEXIM1 DDX39B DDX39B SF3B3 SF3B3 RNPC3 RNPC3 PRPF8 PRPF8 RBM22 RBM22 LOC100685327 LOC100685327 DDX39A DDX39A HNRNPU HNRNPU TUT1 TUT1 LSM4 LSM4 EFTUD2 EFTUD2 HEXIM2 HEXIM2 ENSCAFP00000065931 ENSCAFP00000065931 SNRPC-5 SNRPC-5 ENSCAFP00000063487 ENSCAFP00000063487 ENSCAFP00000062765 ENSCAFP00000062765 LSM4-2 LSM4-2 ENSCAFP00000060782 ENSCAFP00000060782 LSM3-5 LSM3-5 SNRNP35 SNRNP35 SNU13 SNU13 SART3 SART3 ENSCAFP00000054853 ENSCAFP00000054853 CCNT2 CCNT2 ENSCAFP00000051873 ENSCAFP00000051873 LSM3 LSM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNRPC-4U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (158 aa)
LSM3-4U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (107 aa)
LRMDALeucine rich melanocyte differentiation associated. (271 aa)
LSM3-3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
LSM3-2U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
MEPCEMethylphosphate capping enzyme. (700 aa)
SNRPC-3U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (143 aa)
J9P8E9_CANLFRibonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
LOC100686524Uncharacterized protein. (178 aa)
RBM41RNA binding motif protein 41. (484 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (159 aa)
PRPF31Nop domain-containing protein. (499 aa)
PRPF4Pre-mRNA processing factor 4. (522 aa)
LSM10LSM10, U7 small nuclear RNA associated. (123 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (439 aa)
TOE1Target of EGR1, exonuclease. (510 aa)
SNRPAUncharacterized protein. (282 aa)
LRTOMTUncharacterized protein. (192 aa)
KMT5ALysine methyltransferase 5A. (389 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (725 aa)
SNRPA1Small nuclear ribonucleoprotein polypeptide A. (255 aa)
ISG20Interferon stimulated exonuclease gene 20. (171 aa)
LARP7La ribonucleoprotein domain family member 7. (567 aa)
DDX21DExD-box helicase 21. (785 aa)
GEMIN5Gem nuclear organelle associated protein 5. (1508 aa)
J9NXJ9_CANLFRRM domain-containing protein. (123 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (489 aa)
SNRPC-2U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
SNRPB2Uncharacterized protein. (225 aa)
HEXIM1HEXIM P-TEFb complex subunit 1. (229 aa)
DDX39BSpliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...] (428 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
RNPC3RNA binding region (RNP1, RRM) containing 3. (518 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
RBM22RNA binding motif protein 22. (420 aa)
LOC100685327Uncharacterized protein. (1707 aa)
DDX39ADExD-box helicase 39A. (427 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (805 aa)
TUT1Terminal uridylyl transferase 1, U6 snRNA-specific. (873 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (1009 aa)
HEXIM2HEXIM P-TEFb complex subunit 2. (285 aa)
ENSCAFP00000065931Uncharacterized protein. (85 aa)
SNRPC-5U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (174 aa)
ENSCAFP00000063487RRM domain-containing protein. (88 aa)
ENSCAFP00000062765RRM domain-containing protein. (88 aa)
LSM4-2U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (146 aa)
ENSCAFP00000060782RRM_3 domain-containing protein. (111 aa)
LSM3-5U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
SNRNP35Small nuclear ribonucleoprotein U11/U12 subunit 35. (226 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (163 aa)
SART3Spliceosome associated factor 3, U4/U6 recycling protein. (1100 aa)
ENSCAFP00000054853Uncharacterized protein. (217 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (745 aa)
ENSCAFP00000051873Uncharacterized protein. (199 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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