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| | ITK | Tyrosine-protein kinase. (620 aa) |
| | CD19 | CD19 molecule. (611 aa) |
| | TSHR | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (329 aa) |
| | IL6R | Interleukin 6 receptor. (468 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (685 aa) |
| | GBA | Glucosylceramidase. (536 aa) |
| | DOCK2 | Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa) |
| | KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa) |
| | GON4L | Myb-like domain-containing protein. (2227 aa) |
| | SEMA4A | Semaphorin 4A; Belongs to the semaphorin family. (805 aa) |
| | TBX21 | T-box transcription factor 21. (535 aa) |
| | RORA | RAR related orphan receptor A. (528 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2647 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (248 aa) |
| | IKZF3 | IKAROS family zinc finger 3. (509 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | GPS2 | G protein pathway suppressor 2. (327 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (936 aa) |
| | FOXP3 | Forkhead box P3. (452 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | STAT5B | Signal transducer and activator of transcription. (787 aa) |
| | CRACR2A | Calcium release activated channel regulator 2A. (718 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1132 aa) |
| | CLEC4E | C-type lectin domain family 4 member E. (226 aa) |
| | BCL6 | B-cell lymphoma 6 protein. (706 aa) |
| | CCR9 | Chemokine C-C motif receptor 9; Belongs to the G-protein coupled receptor 1 family. (367 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | SP3 | Sp3 transcription factor. (716 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (594 aa) |
| | PATZ1 | POZ/BTB and AT hook containing zinc finger 1. (687 aa) |
| | HECTD1 | HECT domain E3 ubiquitin protein ligase 1. (2609 aa) |
| | FCER1G | Fc fragment of IgE receptor Ig. (86 aa) |
| | CD79B | CD79b molecule. (222 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule; Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those [...] (342 aa) |
| | ZNF683 | Zinc finger protein 683. (492 aa) |
| | HLX | H2.0 like homeobox. (448 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa) |
| | AIRE | Autoimmune regulator. (583 aa) |
| | NOTCH2 | Notch receptor 2. (2726 aa) |
| | PKNOX1 | PBX/knotted 1 homeobox 1. (436 aa) |
| | DCAF1 | DDB1 and CUL4 associated factor 1. (1506 aa) |
| | ENTPD7 | Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa) |
| | NKX2-3 | NK2 homeobox 3. (365 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (732 aa) |
| | CDH17 | Cadherin 17. (832 aa) |
| | IRF4 | Interferon regulatory factor 4. (428 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | ADGRG3 | Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (559 aa) |
| | LMBR1L | Limb development membrane protein 1 like; Belongs to the LIMR family. (489 aa) |
| | IL7 | Interleukin 7. (155 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1191 aa) |
| | ARMC5 | Armadillo repeat containing 5. (976 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (445 aa) |
| | ZBTB7A | Zinc finger and BTB domain containing 7A. (714 aa) |
| | LOC484865 | C-type lectin domain-containing protein. (224 aa) |
| | CD8A | T-cell surface glycoprotein CD8 alpha chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Sr [...] (359 aa) |
| | LOC100683567 | Uncharacterized protein. (196 aa) |
| | POU1F1 | Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'. (291 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (725 aa) |
| | CEBPG | CCAAT enhancer binding protein gamma. (147 aa) |
| | CHD7 | Chromodomain helicase DNA binding protein 7. (2995 aa) |
| | TOX | Thymocyte selection associated high mobility group box. (526 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1071 aa) |
| | RAG2 | Recombination activating 2. (527 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | CMTM7 | CKLF like MARVEL transmembrane domain containing 7. (163 aa) |
| | PAX1 | Paired box 1. (448 aa) |
| | AXL | AXL receptor tyrosine kinase. (879 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | BCL3 | BCL3 transcription coactivator. (566 aa) |
| | RELB | RELB proto-oncogene, NF-kB subunit. (560 aa) |
| | GIMAP1 | GTPase, IMAP family member 1. (295 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (689 aa) |
| | IL21 | Interleukin-21; Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity); Bel [...] (146 aa) |
| | TRAF3IP2 | TRAF3 interacting protein 2. (560 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (772 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | GLI3 | GLI family zinc finger 3. (1590 aa) |
| | IKZF1 | IKAROS family zinc finger 1. (684 aa) |
| | TNFSF8 | Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family. (234 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain containing 2. (361 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | NFIL3 | Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T- cells. Competes for the same consensus-binding site with PAR DNA- bi [...] (462 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (975 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | SRF | Serum response factor. (508 aa) |
| | ANXA1 | Annexin. (345 aa) |
| | FBXO7 | F-box protein 7. (523 aa) |
| | IFNK | Interferon kappa. (209 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (340 aa) |
| | IFNB1 | Interferon-beta. (186 aa) |
| | MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (315 aa) |
| | RAB44 | RAB44, member RAS oncogene family. (953 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa) |
| | LOC102156614 | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family. (333 aa) |
| | EP300 | E1A binding protein p300. (2308 aa) |
| | THEMIS | Thymocyte selection associated. (653 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (243 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (132 aa) |
| | IRF1 | Interferon regulatory factor 1. (437 aa) |
| | LOC481728 | Uncharacterized protein. (517 aa) |
| | FNIP1 | Folliculin interacting protein 1. (1168 aa) |
| | MALT1 | MALT1 paracaspase. (758 aa) |
| | CD4 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (462 aa) |
| | ADA | Adenosine deaminase. (402 aa) |
| | LOC100687778 | Interferon alpha-1/2-like. (187 aa) |
| | POU2AF1 | POU class 2 homeobox associating factor 1. (260 aa) |
| | TPD52 | Uncharacterized protein. (366 aa) |
| | LOC100683045 | Interferon alpha-1/2-like. (187 aa) |
| | LY6D | Lymphocyte antigen 6 family member D. (179 aa) |
| | GPR89A | Uncharacterized protein. (466 aa) |
| | ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (400 aa) |
| | LYL1 | Uncharacterized protein. (316 aa) |
| | LOC100688005 | Interferon alpha-1/2-like. (187 aa) |
| | ENSCAFP00000058563 | Uncharacterized protein. (148 aa) |
| | ENSCAFP00000058303 | BZIP domain-containing protein. (155 aa) |
| | DCLRE1C | DNA cross-link repair 1C. (715 aa) |
| | LOC100683265 | Interferon alpha-1/2-like. (187 aa) |
| | CD83 | CD83 molecule. (229 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (481 aa) |
| | TYRO3 | TYRO3 protein tyrosine kinase. (902 aa) |
| | LOC100682977 | Interferon alpha-1/2-like. (187 aa) |
| | JDP2 | Jun dimerization protein 2. (358 aa) |
| | IL18R1 | Interleukin 18 receptor 1. (718 aa) |
| | SYK | Tyrosine-protein kinase. (699 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1385 aa) |
| | LOC100687857 | Uncharacterized protein. (187 aa) |
| | ENSCAFP00000053963 | BHLH domain-containing protein. (225 aa) |
| | ENSCAFP00000053846 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (296 aa) |
| | CD79A | B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...] (284 aa) |
| | LOC100688084 | Interferon alpha-1/2. (187 aa) |
| | ENSCAFP00000053409 | SEFIR domain-containing protein. (199 aa) |
| | JMJD6 | Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (525 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (246 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] (228 aa) |
| | IFNA7 | Interferon-alpha. (187 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (619 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (903 aa) |
| | CD28 | CD28 molecule. (246 aa) |
| | IRF8 | Interferon regulatory factor 8. (460 aa) |
| | LOC100685213 | Interferon alpha-1/2. (187 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1029 aa) |
| | STAT3 | Signal transducer and activator of transcription. (793 aa) |
| | LOC100683123 | Interferon alpha-1/2-like. (187 aa) |
| | ENSCAFP00000049600 | Uncharacterized protein. (108 aa) |
| | ENSCAFP00000049310 | Uncharacterized protein. (176 aa) |
| | SOX13 | SRY-box 13. (618 aa) |
| | RIPK3 | Protein kinase domain-containing protein. (423 aa) |
| | LOC100687928 | Interferon alpha-1/2. (187 aa) |
| | ZAP70 | Tyrosine-protein kinase. (592 aa) |
| | LOC100683202 | Interferon alpha-1/2; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs to the alpha/beta interferon family. (187 aa) |
| | STAT6 | Signal transducer and activator of transcription. (927 aa) |
| | LOC100687692 | Uncharacterized protein. (187 aa) |
| | CLEC4D | C-type lectin domain family 4 member D. (263 aa) |
| | PTGER4 | Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (610 aa) |
| | IFNA5 | Interferon alpha-3; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs to the alpha/beta interferon family. (187 aa) |
| | LOC100683416 | Uncharacterized protein. (178 aa) |
| | CD74 | CD74 molecule. (272 aa) |
| | NCAPH2 | Non-SMC condensin II complex subunit H2. (602 aa) |
| | CCR6 | C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (470 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (534 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (815 aa) |
| | BTK | Tyrosine-protein kinase. (687 aa) |
| | TCF7 | Transcription factor 7. (484 aa) |
| | C9H17orf99 | Chromosome 9 C17orf99 homolog. (383 aa) |
| | ZBTB1 | Zinc finger/BTB domain-containing protein 1 isoform 1. (712 aa) |
| | RUNX2 | RUNX family transcription factor 2. (476 aa) |
| | EOMES | Eomesodermin. (707 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | J9P859_CANLF | Galectin. (135 aa) |
| | J9P7C5_CANLF | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (252 aa) |
| | IL2RG | Cytokine receptor common subunit gamma; Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (By similarity). Belongs to the type I cytokine receptor family. Type 5 subfamily. (373 aa) |
| | HMGB1 | High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functio [...] (240 aa) |
| | LGALS1 | Galectin. (196 aa) |
| | ENSCAFP00000040898 | Cathepsin L1 Cathepsin L1 heavy chain Cathepsin L1 light chain. (333 aa) |
| | FUT7 | Fucosyltransferase 7. (342 aa) |
| | MERTK | MER proto-oncogene, tyrosine kinase. (996 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (381 aa) |
| | NHEJ1 | Non-homologous end joining factor 1. (299 aa) |
| | CD3D | CD3d molecule. (194 aa) |
| | ITFG2 | Integrin alpha FG-GAP repeat containing 2. (487 aa) |
| | ZFP36L2 | ZFP36 ring finger protein like 2. (456 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (842 aa) |
| | PREX1 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1585 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | TNFSF13B | Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family. (370 aa) |
| | GPR18 | G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (331 aa) |
| | SOX4 | Transcription factor SOX. (344 aa) |
| | IRF2BP2 | Interferon regulatory factor 2 binding protein 2. (593 aa) |
| | SLAMF6 | SLAM family member 6. (228 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (910 aa) |
| | CBFB | Core-binding factor subunit beta. (82 aa) |
| | LRRC8A | Leucine rich repeat containing 8 VRAC subunit A. (810 aa) |
| | PLCG2 | Phosphoinositide phospholipase C. (1336 aa) |
| | ABL1 | Tyrosine-protein kinase. (1150 aa) |
| | TSC1 | TSC complex subunit 1. (1169 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (439 aa) |
| | NRARP | NOTCH regulated ankyrin repeat protein. (114 aa) |
| | CD40LG | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (260 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (408 aa) |
| | FOXN1 | Forkhead box N1. (643 aa) |
| | LEPR | Leptin receptor. (1166 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (845 aa) |
| | JAG2 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1135 aa) |
| | TMEM98 | Transmembrane protein 98. (226 aa) |
| | BCL11B | BAF chromatin remodeling complex subunit BCL11B. (917 aa) |
