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| | TNFRSF11A | TNF receptor superfamily member 11a. (648 aa) |
| | IL23A | Interleukin 23 subunit alpha. (193 aa) |
| | USP15 | Ubiquitin specific peptidase 15; Belongs to the peptidase C19 family. (1109 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) |
| | LTA | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). (204 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (132 aa) |
| | CXCL14 | C-X-C motif chemokine ligand 14. (99 aa) |
| | CCN4 | Cellular communication network factor 4. (362 aa) |
| | DEF6 | DEF6 guanine nucleotide exchange factor. (631 aa) |
| | MATR3 | Uncharacterized protein. (864 aa) |
| | IL33 | Interleukin-33; Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury (By similarity). (263 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | TTBK1 | Tau tubulin kinase 1. (818 aa) |
| | POLR3B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa) |
| | TXK | Tyrosine-protein kinase. (551 aa) |
| | CCL27 | Cutaneous T cell attracting chemokine. (119 aa) |
| | CCL19 | C-C motif chemokine. (115 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa) |
| | IL18RAP | Interleukin 18 receptor accessory protein. (582 aa) |
| | IL1RL1 | Interleukin 1 receptor like 1. (557 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (353 aa) |
| | NINJ1 | Ninjurin 1. (151 aa) |
| | ANKRD17 | Ankyrin repeat domain 17. (2491 aa) |
| | CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus; Belongs to the intercrine alpha (chemokine CxC) family. (137 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (964 aa) |
| | AKIRIN2 | Akirin 2. (203 aa) |
| | AKIRIN1 | Akirin 1. (193 aa) |
| | IRF3 | Interferon regulatory factor 3. (281 aa) |
| | SFPQ | Splicing factor proline and glutamine rich. (702 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (772 aa) |
| | FKBP1B | Peptidylprolyl isomerase. (108 aa) |
| | IL21 | Interleukin-21; Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity); Bel [...] (146 aa) |
| | TNIP3 | TNFAIP3 interacting protein 3. (452 aa) |
| | NAPEPLD | N-acyl phosphatidylethanolamine phospholipase D. (428 aa) |
| | LOC100687459 | AIG1-type G domain-containing protein. (341 aa) |
| | NECTIN2 | Nectin cell adhesion molecule 2. (541 aa) |
| | EMILIN1 | Elastin microfibril interfacer 1. (1015 aa) |
| | PVR | PVR cell adhesion molecule. (405 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (512 aa) |
| | OPTN | Optineurin. (608 aa) |
| | CXCL17 | C-X-C motif chemokine ligand 17. (119 aa) |
| | MEGF8 | Multiple EGF like domains 8. (439 aa) |
| | B9D2 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | GHRL | Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family. (117 aa) |
| | NMI | N-myc and STAT interactor. (308 aa) |
| | STING1 | Transmembrane protein 173. (375 aa) |
| | ANKHD1 | ANK_REP_REGION domain-containing protein. (2650 aa) |
| | LAMP1 | Lysosomal associated membrane protein 1. (413 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1133 aa) |
| | NLRP6 | NLR family pyrin domain containing 6. (911 aa) |
| | F6Y518_CANLF | IRF-3 domain-containing protein. (90 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (580 aa) |
| | FFAR2 | Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (331 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (327 aa) |
| | LSM14A | LSM14A mRNA processing body assembly factor. (448 aa) |
| | PSPC1 | Paraspeckle component 1. (505 aa) |
| | CD180 | CD180 molecule. (661 aa) |
| | VAMP8 | Vesicle associated membrane protein 8. (101 aa) |
| | P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa) |
| | CCDC142 | Coiled-coil domain containing 142. (749 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (758 aa) |
| | THBS1 | Thrombospondin 1. (1456 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | F2RL1 | Protease-activated receptor 2. (397 aa) |
| | TOMM70 | Translocase of outer mitochondrial membrane 70. (609 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (669 aa) |
| | MSTN | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (375 aa) |
| | POLR3D | RNA polymerase III subunit D. (398 aa) |
| | NOD2 | Uncharacterized protein. (1013 aa) |
| | CD81 | Tetraspanin. (233 aa) |
| | RIPOR2 | RHO family interacting cell polarization regulator 2. (1066 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa) |
| | LGMN | Legumain. (470 aa) |
| | HABP2 | Hyaluronan binding protein 2. (557 aa) |
| | CD160 | CD160 molecule. (277 aa) |
| | PUM1 | Pumilio RNA binding family member 1. (1224 aa) |
| | PRSS56 | Serine protease 56; Belongs to the peptidase S1 family. (616 aa) |
| | POLR3C | RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa) |
| | APOH | Beta-2-glycoprotein 1; Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. (345 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (619 aa) |
| | ZNFX1 | Zinc finger NFX1-type containing 1. (1918 aa) |
| | FCGR1A | Uncharacterized protein. (428 aa) |
| | CRTAM | Cytotoxic and regulatory T cell molecule. (393 aa) |
| | LOC488622 | Uncharacterized protein. (534 aa) |
| | MNDA | Myeloid cell nuclear differentiation antigen. (507 aa) |
| | MOSPD2 | Motile sperm domain containing 2. (518 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | IRF9 | Uncharacterized protein. (1136 aa) |
| | LOC610648 | RNA binding motif protein 14. (620 aa) |
| | OSM | Oncostatin M. (247 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule; Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those [...] (342 aa) |
| | SNX4 | Sorting nexin 4. (433 aa) |
| | COCH | Cochlin. (805 aa) |
| | PLA2G3 | Phospholipase A2 group III. (512 aa) |
| | SH2D1B | SH2 domain containing 1B. (153 aa) |
| | F1PCP9_CANLF | Uncharacterized protein. (121 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | CADM1 | Cell adhesion molecule 1. (474 aa) |
| | HSPB1 | Heat shock protein beta-1; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins. (206 aa) |
| | ZP3 | Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. (441 aa) |
| | CCR2 | C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | IL16 | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1376 aa) |
| | MCU | Mitochondrial calcium uniporter. (350 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa) |
| | TNFSF4 | Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (183 aa) |
| | LAG3 | Lymphocyte activating 3. (326 aa) |
| | MMP8 | Matrix metallopeptidase 8. (476 aa) |
| | GHSR | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (291 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | PPM1F | Protein phosphatase, Mg2+/Mn2+ dependent 1F. (440 aa) |
| | OCM2 | Uncharacterized protein; Belongs to the parvalbumin family. (109 aa) |
| | NLRP1 | NLR family pyrin domain containing 1. (1432 aa) |
| | C1QBP | Complement C1q binding protein. (272 aa) |
| | STAT5B | Signal transducer and activator of transcription. (787 aa) |
| | DHX58 | DExH-box helicase 58. (678 aa) |
| | UBE2K | Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa) |
| | IL17RA | Interleukin 17 receptor A. (866 aa) |
| | MMRN2 | Multimerin 2. (1264 aa) |
| | TLR10 | Toll like receptor 10; Belongs to the Toll-like receptor family. (807 aa) |
| | TMEM102 | Transmembrane protein 102. (503 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (213 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (283 aa) |
| | NUPR1 | Nuclear protein 1, transcriptional regulator. (82 aa) |
| | CXCR3 | C-X-C chemokine receptor type 3; Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response (By similarity). (368 aa) |
| | ABCC1 | Multidrug resistance-associated protein 1; Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (By similarity). Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (By similarity). [...] (1541 aa) |
| | S100A14 | S100 calcium binding protein A14; Belongs to the S-100 family. (104 aa) |
| | HAVCR1 | Ig-like domain-containing protein. (304 aa) |
| | RIOK3 | Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (519 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (845 aa) |
| | OSMR | Oncostatin M receptor. (968 aa) |
| | ZBP1 | Z-DNA binding protein 1. (242 aa) |
| | STK26 | Serine/threonine kinase 26. (443 aa) |
| | F1PXS7_CANLF | Protein kinase domain-containing protein. (232 aa) |
| | SERPINF2 | Serpin family F member 2; Belongs to the serpin family. (491 aa) |
| | FLNA | Filamin A. (2646 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (536 aa) |
| | C2CD4C | C2 calcium dependent domain containing 4C. (568 aa) |
| | PLCG2 | Phosphoinositide phospholipase C. (1336 aa) |
| | KARS1 | Lysine--tRNA ligase. (625 aa) |
| | TRADD | TNFRSF1A associated via death domain. (312 aa) |
| | TIRAP | TIR domain containing adaptor protein. (406 aa) |
| | TLR9-2 | Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). (1032 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa) |
| | CXCL10 | C-X-C motif chemokine 10; Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pat [...] (98 aa) |
| | SLAMF6 | SLAM family member 6. (228 aa) |
| | SCG2 | Secretogranin II. (575 aa) |
| | HEXIM1 | HEXIM P-TEFb complex subunit 1. (229 aa) |
| | KLK8 | Uncharacterized protein; Belongs to the peptidase S1 family. (684 aa) |
| | DEFB124 | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (70 aa) |
| | CXCL13 | C-X-C motif chemokine. (110 aa) |
| | IFI35 | Interferon induced protein 35. (286 aa) |
| | C3AR1 | Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (484 aa) |
| | KLRK1 | Killer cell lectin like receptor K1. (217 aa) |
| | KLRD1 | Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. (179 aa) |
| | J9NRS1_CANLF | SCY domain-containing protein. (213 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (346 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa) |
| | CXCL12 | SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (117 aa) |
| | CASP6 | Caspase 6; Belongs to the peptidase C14A family. (497 aa) |
| | PDCD4 | Programmed cell death 4. (469 aa) |
| | TRIM62 | Tripartite motif containing 62. (415 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (205 aa) |
| | BMP6 | Bone morphogenetic protein 6. (335 aa) |
| | PDE2A | Phosphodiesterase. (918 aa) |
| | XRCC5 | X-ray repair cross complementing 5. (829 aa) |
| | LOC100686507 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (172 aa) |
| | EREG | Epiregulin. (160 aa) |
| | ZNF580 | Zinc finger protein 580. (172 aa) |
| | SCARF1 | Scavenger receptor class F member 1. (932 aa) |
| | CMKLR1 | Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (365 aa) |
| | CD226 | CD226 molecule. (347 aa) |
| | J9P3C7_CANLF | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa) |
| | NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9. (868 aa) |
| | CLNK | Cytokine dependent hematopoietic cell linker. (443 aa) |
| | STX3 | Syntaxin 3; Belongs to the syntaxin family. (297 aa) |
| | CCL26 | C-C motif chemokine 26; Chemoattractant for eosinophils and basophils. Acts as a ligand for C-C chemokine receptor CCR3 which triggers (Ca2+) mobilization in eosinophils. (94 aa) |
| | LGALS1 | Galectin. (196 aa) |
| | SCARF2 | Scavenger receptor class F member 2. (759 aa) |
| | HMGB1 | High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functio [...] (240 aa) |
| | SH2D1A | SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1421 aa) |
| | TNFSF14 | Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. (240 aa) |
| | FCN1 | Ficolin 1. (322 aa) |
| | VEGFA | Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (495 aa) |
| | J9P859_CANLF | Galectin. (135 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | PTPN9 | SIN3 transcription regulator family member A. (1303 aa) |
| | J9P9V2_CANLF | Uncharacterized protein. (73 aa) |
| | NCR3 | Natural cytotoxicity triggering receptor 3. (191 aa) |
| | LY96 | Lymphocyte antigen 96. (160 aa) |
| | J9PB83_CANLF | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (120 aa) |
| | SWAP70 | Switching B cell complex subunit SWAP70. (590 aa) |
| | LDLR | Low density lipoprotein receptor. (888 aa) |
| | NTRK3 | Tyrosine-protein kinase receptor. (827 aa) |
| | ACOD1 | Aconitate decarboxylase 1. (482 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (519 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (967 aa) |
| | CCR6 | C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (470 aa) |
| | IL17A | Interleukin 17A. (156 aa) |
| | STAP1 | Signal transducing adaptor family member 1. (318 aa) |
| | CD74 | CD74 molecule. (272 aa) |
| | PTGER4 | Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (610 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (807 aa) |
| | ENSCAFP00000046796 | PTN_MK_N domain-containing protein. (115 aa) |
| | S100A9 | EF-hand domain-containing protein; Belongs to the S-100 family. (186 aa) |
| | GPSM3 | G protein signaling modulator 3. (208 aa) |
| | PLA2G5 | Phospholipase A(2). (308 aa) |
| | PRKD2 | Protein kinase D2. (1018 aa) |
| | NXPE3 | NFKB inhibitor zeta. (1002 aa) |
| | MAPK3-2 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | GAS6 | Growth arrest specific 6. (661 aa) |
| | ADAM10 | ADAM metallopeptidase domain 10. (750 aa) |
| | FGF18 | Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (335 aa) |
| | ENSCAFP00000049310 | Uncharacterized protein. (176 aa) |
| | TBK1 | TANK binding kinase 1. (772 aa) |
| | OXSR1 | Oxidative stress responsive kinase 1. (552 aa) |
| | ENSCAFP00000050490 | Uncharacterized protein. (67 aa) |
| | FEM1A | Fem-1 homolog A. (673 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (523 aa) |
| | PARP9 | Poly(ADP-ribose) polymerase family member 9. (1030 aa) |
| | VAMP7 | Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (250 aa) |
| | LGALS2 | Galectin. (191 aa) |
| | CD28 | CD28 molecule. (246 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1003 aa) |
| | THBS4 | Thrombospondin 4. (1038 aa) |
| | DEFB114 | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (68 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1257 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (718 aa) |
| | CYBA | Cytochrome b-245 alpha chain. (336 aa) |
| | ANO6 | Anoctamin. (937 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | CCR1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (355 aa) |
| | ENSCAFP00000054811 | Uncharacterized protein. (423 aa) |
| | SYK | Tyrosine-protein kinase. (699 aa) |
| | ENSCAFP00000055576 | Uncharacterized protein. (133 aa) |
| | ENSCAFP00000055760 | V-SNARE coiled-coil homology domain-containing protein. (107 aa) |
| | PDGFB | Platelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers wit [...] (341 aa) |
| | IL34 | Interleukin 34. (261 aa) |
| | PUM2 | Pumilio RNA binding family member 2. (1053 aa) |
| | LRSAM1 | Leucine rich repeat and sterile alpha motif containing 1. (743 aa) |
| | XRCC6 | X-ray repair cross complementing 6. (612 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (869 aa) |
| | CSF1 | Colony stimulating factor 1. (587 aa) |
| | IL17F | Interleukin 17F. (196 aa) |
| | SLIT2 | Slit guidance ligand 2. (1543 aa) |
| | GLTP | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (920 aa) |
| | SETD4 | SET domain containing 4. (510 aa) |
| | PQBP1 | Polyglutamine binding protein 1. (358 aa) |
| | CD47 | CD47 molecule. (439 aa) |
| | CDH13 | Cadherin 13. (713 aa) |
| | AGER | Advanced glycosylation end product-specific receptor variant C. (396 aa) |
| | CCL24 | C-C motif chemokine 24; Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Binds to CCR3 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (232 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (752 aa) |
| | PARK7 | Parkinsonism associated deglycase. (297 aa) |
| | IDO1 | Indoleamine 2,3-dioxygenase 1. (421 aa) |
| | FABP4 | Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (166 aa) |
| | TRIM56 | Tripartite motif containing 56. (771 aa) |
| | STK39 | Serine/threonine kinase 39. (555 aa) |
| | SMOC2 | SPARC related modular calcium binding 2. (667 aa) |
| | CCL3 | C-C motif chemokine 3; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (159 aa) |
| | PTN | Pleiotrophin. (202 aa) |
| | RARRES2 | Retinoic acid receptor responder 2. (235 aa) |
| | CGAS | Cyclic GMP-AMP synthase. (501 aa) |
| | LY86 | Lymphocyte antigen 86. (215 aa) |
