Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADA | IL2 | ENSCAFP00000063170 | ENSCAFP00000005941 | Adenosine deaminase. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | 0.595 |
| ADA | IL2RG | ENSCAFP00000063170 | ENSCAFP00000041465 | Adenosine deaminase. | Cytokine receptor common subunit gamma; Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (By similarity). Belongs to the type I cytokine receptor family. Type 5 subfamily. | 0.485 |
| AXL | GAS6 | ENSCAFP00000007520 | ENSCAFP00000048221 | AXL receptor tyrosine kinase. | Growth arrest specific 6. | 0.989 |
| BCL6 | CD27 | ENSCAFP00000020491 | ENSCAFP00000022326 | B-cell lymphoma 6 protein. | CD27 molecule. | 0.528 |
| BCL6 | FOXP3 | ENSCAFP00000020491 | ENSCAFP00000023435 | B-cell lymphoma 6 protein. | Forkhead box P3. | 0.828 |
| BCL6 | GATA3 | ENSCAFP00000020491 | ENSCAFP00000007467 | B-cell lymphoma 6 protein. | GATA binding protein 3. | 0.548 |
| BCL6 | IFNG | ENSCAFP00000020491 | ENSCAFP00000000588 | B-cell lymphoma 6 protein. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.554 |
| BCL6 | IL10 | ENSCAFP00000020491 | ENSCAFP00000016812 | B-cell lymphoma 6 protein. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.524 |
| BCL6 | IL2 | ENSCAFP00000020491 | ENSCAFP00000005941 | B-cell lymphoma 6 protein. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | 0.535 |
| BCL6 | IL4 | ENSCAFP00000020491 | ENSCAFP00000001253 | B-cell lymphoma 6 protein. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | 0.778 |
| BCL6 | STAT5A | ENSCAFP00000020491 | ENSCAFP00000022653 | B-cell lymphoma 6 protein. | Signal transducer and activator of transcription. | 0.431 |
| BCL6 | XBP1 | ENSCAFP00000020491 | ENSCAFP00000017593 | B-cell lymphoma 6 protein. | BZIP domain-containing protein. | 0.726 |
| CCL19 | CD83 | ENSCAFP00000002873 | ENSCAFP00000056788 | C-C motif chemokine. | CD83 molecule. | 0.414 |
| CCL19 | FOXP3 | ENSCAFP00000002873 | ENSCAFP00000023435 | C-C motif chemokine. | Forkhead box P3. | 0.427 |
| CCL19 | IFNG | ENSCAFP00000002873 | ENSCAFP00000000588 | C-C motif chemokine. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.636 |
| CCL19 | IL10 | ENSCAFP00000002873 | ENSCAFP00000016812 | C-C motif chemokine. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.538 |
| CCL19 | IL2 | ENSCAFP00000002873 | ENSCAFP00000005941 | C-C motif chemokine. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | 0.522 |
| CCL19 | IL4 | ENSCAFP00000002873 | ENSCAFP00000001253 | C-C motif chemokine. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | 0.616 |
| CCL19 | IL7 | ENSCAFP00000002873 | ENSCAFP00000012305 | C-C motif chemokine. | Interleukin 7. | 0.573 |
| CD27 | BCL6 | ENSCAFP00000022326 | ENSCAFP00000020491 | CD27 molecule. | B-cell lymphoma 6 protein. | 0.528 |
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