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IL23A | Interleukin 23 subunit alpha. (193 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
KLF10 | Kruppel like factor 10. (479 aa) | ||||
TNFRSF11B | Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (132 aa) | ||||
LRRC17 | Leucine rich repeat containing 17. (463 aa) | ||||
TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (512 aa) | ||||
TMEM178A | Transmembrane protein 178A. (297 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (580 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (725 aa) | ||||
POU4F2 | POU domain protein. (408 aa) | ||||
FBXW7 | F-box and WD repeat domain containing 7. (754 aa) | ||||
NOTCH2 | Notch receptor 2. (2726 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (521 aa) | ||||
SLC9B2 | Solute carrier family 9 member B2. (537 aa) | ||||
GPR137B | G protein-coupled receptor 137B. (398 aa) | ||||
TCTA | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. (105 aa) | ||||
UBASH3B | Ubiquitin associated and SH3 domain containing B. (637 aa) | ||||
CREB1 | cAMP responsive element binding protein 1. (341 aa) | ||||
LTF | Uncharacterized protein; Belongs to the transferrin family. (708 aa) | ||||
GPR137 | G protein-coupled receptor 137. (396 aa) | ||||
FBN1 | Uncharacterized protein. (2871 aa) | ||||
TFE3 | Transcription factor binding to IGHM enhancer 3. (571 aa) | ||||
PRXL2A | Peroxiredoxin like 2A. (489 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2647 aa) | ||||
FBXW9 | F-box and WD repeat domain containing 9. (458 aa) | ||||
GPR68 | G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (360 aa) | ||||
FSTL3 | Follistatin like 3. (264 aa) | ||||
TOB2 | Transducer of ERBB2, 2. (336 aa) | ||||
OCSTAMP | Osteoclast stimulatory transmembrane protein. (484 aa) | ||||
NF1 | Neurofibromin 1. (2784 aa) | ||||
CEBPB | CCAAT/enhancer-binding protein. (346 aa) | ||||
SFRP1 | Secreted frizzled related protein 1. (458 aa) | ||||
IAPP | Islet amyloid polypeptide; Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism; Belongs to the calcitonin family. (89 aa) | ||||
NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9. (868 aa) | ||||
IL17A | Interleukin 17A. (156 aa) | ||||
GPR55 | G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (338 aa) | ||||
MITF | Melanocyte inducing transcription factor. (533 aa) | ||||
TNFAIP6 | TNF alpha induced protein 6. (296 aa) | ||||
TREM2 | Triggering receptor expressed on myeloid cells 2. (523 aa) | ||||
PPARGC1B | PPARG coactivator 1 beta. (1028 aa) | ||||
TMEM64 | Transmembrane protein 64. (262 aa) | ||||
PIAS3 | Protein inhibitor of activated STAT 3. (849 aa) | ||||
INPP5D | Inositol polyphosphate-5-phosphatase D. (1501 aa) | ||||
FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (704 aa) | ||||
RASSF2 | Ras association domain family member 2. (326 aa) | ||||
CSF1 | Colony stimulating factor 1. (587 aa) | ||||
CCL3 | C-C motif chemokine 3; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (159 aa) |