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| | TNFAIP3 | TNF alpha induced protein 3. (790 aa) |
| | IL26 | Interleukin 26. (171 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (508 aa) |
| | STK3 | Serine/threonine kinase 3. (491 aa) |
| | OSR2 | Odd-skipped related transciption factor 2. (312 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | VIP | Vasoactive intestinal peptide. (170 aa) |
| | TBC1D31 | TBC1 domain family member 31. (1141 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa) |
| | SLURP1 | Secreted LY6/PLAUR domain containing 1. (232 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (340 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2B. (177 aa) |
| | IFT74 | Intraflagellar transport 74. (600 aa) |
| | HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa) |
| | PHOX2B | Paired like homeobox 2B. (314 aa) |
| | B4GALT1 | Beta-1,4-galactosyltransferase 1. (399 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa) |
| | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4074 aa) |
| | DLX5 | Distal-less homeobox 5. (289 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | ODAM | Odontogenic ameloblast-associated protein; Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface; Belongs to the ODAM family. (278 aa) |
| | HOXA5 | Homeobox A5. (381 aa) |
| | EPGN | Epithelial mitogen. (153 aa) |
| | TGFA | EGF-like domain-containing protein. (284 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1141 aa) |
| | MYCN | BHLH domain-containing protein. (180 aa) |
| | OSR1 | Odd-skipped related transcription factor 1. (267 aa) |
| | LOC102151792 | L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (480 aa) |
| | INTU | Inturned planar cell polarity protein. (941 aa) |
| | JCAD | Junctional cadherin 5 associated. (1364 aa) |
| | C5AR2 | Complement component 5a receptor 2. (337 aa) |
| | C5AR1 | C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N- terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (By similarity). (352 aa) |
| | LOC100856461 | Bromo domain-containing protein. (653 aa) |
| | TRIM24 | Tripartite motif containing 24. (1052 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (336 aa) |
| | CNMD | Chondromodulin. (305 aa) |
| | B9D2 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | WDR48 | WD repeat domain 48. (677 aa) |
| | GHRL | Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family. (117 aa) |
| | TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa) |
| | ZFP36 | ZFP36 ring finger protein. (335 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (853 aa) |
| | ZNF703 | Zinc finger protein 703. (604 aa) |
| | BRCA2 | BRCA2 DNA repair associated. (3446 aa) |
| | MTA3 | Metastasis associated 1 family member 3. (771 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa) |
| | PDX1 | Pancreatic and duodenum homeobox 1. (282 aa) |
| | SP1 | Sp1 transcription factor. (782 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (642 aa) |
| | SULF1 | Sulfatase 1. (1146 aa) |
| | GDF5 | Growth differentiation factor 5. (499 aa) |
| | SFRP2 | Secreted frizzled-related protein 2; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. (253 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa) |
| | THBS1 | Thrombospondin 1. (1456 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | VDR | Vitamin D receptor. (432 aa) |
| | EGR3 | Early growth response 3. (387 aa) |
| | IFT52 | Intraflagellar transport 52. (446 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (732 aa) |
| | NKX2-3 | NK2 homeobox 3. (365 aa) |
| | NRAS | Uncharacterized protein. (189 aa) |
| | NOD2 | Uncharacterized protein. (1013 aa) |
| | IFT57 | Intraflagellar transport 57. (482 aa) |
| | NOTCH2 | Notch receptor 2. (2726 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | AIMP1 | Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (321 aa) |
| | PDCD6 | Programmed cell death 6. (187 aa) |
| | APOH | Beta-2-glycoprotein 1; Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. (345 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (619 aa) |
| | HLX | H2.0 like homeobox. (448 aa) |
| | MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (179 aa) |
| | EAF2 | ELL associated factor 2. (556 aa) |
| | ST8SIA1 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (356 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | IRF6 | Interferon regulatory factor 6. (462 aa) |
| | ECM1 | Extracellular matrix protein 1. (542 aa) |
| | TGM1 | Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity); Belongs to the transglutaminase superfamily. Transglutaminase family. (816 aa) |
| | KDF1 | Keratinocyte differentiation factor 1. (397 aa) |
| | SFN | Stratifin; Belongs to the 14-3-3 family. (248 aa) |
| | VASH2 | Vasohibin 2. (355 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. (198 aa) |
| | OVOL1 | Ovo like transcriptional repressor 1. (267 aa) |
| | SIRT1 | Sirtuin 1. (745 aa) |
| | ARX | Aristaless related homeobox. (574 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | WDR77 | WD repeat domain 77. (475 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | GRN | Granulin precursor. (580 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (964 aa) |
| | IFT80 | WD_REPEATS_REGION domain-containing protein. (640 aa) |
| | PDCD10 | Programmed cell death 10. (212 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa) |
| | BMP4 | TGF_BETA_2 domain-containing protein. (409 aa) |
| | FGF7 | Fibroblast growth factor 7; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation (By similarity). (194 aa) |
| | FGFBP1 | Fibroblast growth factor binding protein 1. (225 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | WDR13 | WD repeat domain 13. (485 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | MMRN2 | Multimerin 2. (1264 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (612 aa) |
| | GDF2 | Growth differentiation factor 2. (420 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | SYNJ2BP | PDZ domain-containing protein. (145 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (213 aa) |
| | NUPR1 | Nuclear protein 1, transcriptional regulator. (82 aa) |
| | PYGO2 | Pygopus family PHD finger 2. (405 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (611 aa) |
| | TNMD | Tenomodulin. (317 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (605 aa) |
| | BCL11B | BAF chromatin remodeling complex subunit BCL11B. (917 aa) |
| | F1PDP1_CANLF | Uncharacterized protein. (3365 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (748 aa) |
| | GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (613 aa) |
| | UHRF1 | Ubiquitin like with PHD and ring finger domains 1. (792 aa) |
| | MYDGF | Myeloid derived growth factor. (173 aa) |
| | LRG1 | Leucine rich alpha-2-glycoprotein 1. (354 aa) |
| | SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (418 aa) |
| | HES5 | Hes family bHLH transcription factor 5. (165 aa) |
| | NRARP | NOTCH regulated ankyrin repeat protein. (114 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (439 aa) |
| | NOTCH1 | Notch receptor 1. (2565 aa) |
| | PIK3CD | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1083 aa) |
| | PROK1 | Prokineticin 1. (113 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa) |
| | MARVELD3 | MARVEL domain containing 3. (464 aa) |
| | ESRP2 | Epithelial splicing regulatory protein 2. (717 aa) |
| | HSF4 | Heat shock factor protein 4; DNA-binding protein that specifically binds heat shock promoter elements (HSE). (492 aa) |
| | GAS1 | Growth arrest specific 1. (385 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (910 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (919 aa) |
| | SCG2 | Secretogranin II. (575 aa) |
| | SERPINB5 | Serpin family B member 5; Belongs to the serpin family. (387 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | TINF2 | TERF1 interacting nuclear factor 2. (452 aa) |
| | NF1 | Neurofibromin 1. (2784 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | A4GNT | Alpha-1,4-N-acetylglucosaminyltransferase. (360 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1405 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa) |
| | NKX2-8 | NK2 homeobox 8. (239 aa) |
| | ZNF304 | Zinc finger protein 304. (660 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (458 aa) |
| | SIX4 | SIX homeobox 4. (804 aa) |
| | BMP6 | Bone morphogenetic protein 6. (335 aa) |
| | NODAL | Nodal growth differentiation factor. (378 aa) |
| | YAP1 | Yes associated protein 1. (325 aa) |
| | SIRT6 | Sirtuin 6. (403 aa) |
| | CAV2 | Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa) |
| | AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (760 aa) |
| | ZNF580 | Zinc finger protein 580. (172 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | RTN4 | Reticulon. (993 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (565 aa) |
| | STXBP4 | Syntaxin binding protein 4. (557 aa) |
| | CCL26 | C-C motif chemokine 26; Chemoattractant for eosinophils and basophils. Acts as a ligand for C-C chemokine receptor CCR3 which triggers (Ca2+) mobilization in eosinophils. (94 aa) |
| | APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (371 aa) |
| | HRAS | Uncharacterized protein. (189 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa) |
| | HMGB1 | High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functio [...] (240 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (477 aa) |
| | VEGFA | Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (495 aa) |
| | RUNX2 | RUNX family transcription factor 2. (476 aa) |
| | NGFR | Nerve growth factor receptor. (429 aa) |
| | RREB1 | Ras responsive element binding protein 1. (1787 aa) |
| | VASH1 | Vasohibin 1. (377 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1125 aa) |
| | STK4 | Serine/threonine kinase 4. (514 aa) |
| | PDCL3 | Phosducin like 3. (303 aa) |
| | DEAF1 | DEAF1 transcription factor. (597 aa) |
| | ENSCAFP00000044371 | Uncharacterized protein. (187 aa) |
| | HPN | Hepsin; Belongs to the peptidase S1 family. (615 aa) |
| | CASK | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4- diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5- tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4. The lipid phosphatase activity is critical for its tumor [...] (403 aa) |
| | FMC1 | Uncharacterized protein. (113 aa) |
| | ENSCAFP00000046796 | PTN_MK_N domain-containing protein. (115 aa) |
| | DLG2 | Discs large MAGUK scaffold protein 2. (1012 aa) |
| | MTSS1 | MTSS I-BAR domain containing 1. (763 aa) |
| | KDM5B | Lysine demethylase 5B. (1557 aa) |
| | PRKD2 | Protein kinase D2. (1018 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (581 aa) |
| | AQP11 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (283 aa) |
| | PROK2 | Prokineticin 2. (105 aa) |
| | FGFR3 | Fibroblast growth factor receptor 3. (978 aa) |
| | BMP2 | Bone morphogenetic protein 2. (436 aa) |
| | STAT1 | Signal transducer and activator of transcription. (774 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (637 aa) |
| | SULF2 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. (883 aa) |
| | LOC100856560 | RING-type domain-containing protein. (207 aa) |
| | ENSCAFP00000049310 | Uncharacterized protein. (176 aa) |
| | ENSCAFP00000049352 | Uncharacterized protein. (90 aa) |
| | PHB2 | Prohibitin. (319 aa) |
| | LIMS2 | LIM zinc finger domain containing 2. (457 aa) |
| | ENSCAFP00000050100 | Uncharacterized protein. (135 aa) |
| | STAT3 | Signal transducer and activator of transcription. (793 aa) |
| | ENSCAFP00000050643 | Uncharacterized protein. (148 aa) |
| | DAB2IP | DAB2 interacting protein. (1283 aa) |
| | FUT1 | L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (365 aa) |
| | PPARD | Peroxisome proliferator-activated receptor delta; Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma- linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand (By similarity). (473 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (551 aa) |
| | EGFL7 | EGF like domain multiple 7. (542 aa) |
| | ENSCAFP00000053718 | Uncharacterized protein. (290 aa) |
| | THBS4 | Thrombospondin 4. (1038 aa) |
| | PTCH1 | Patched 1. (1449 aa) |
| | AGGF1 | Angiogenic factor with G-patch and FHA domains 1. (852 aa) |
| | MCC | MCC regulator of WNT signaling pathway. (828 aa) |
| | EMC10 | ER membrane protein complex subunit 10. (274 aa) |
| | CDH3 | Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (933 aa) |
| | PDGFB | Platelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers wit [...] (341 aa) |
| | EPPK1 | Uncharacterized protein. (2948 aa) |
| | RB1 | RB transcriptional corepressor 1. (927 aa) |
| | HMX2 | H6 family homeobox 2. (413 aa) |
| | ALDH1A2 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (555 aa) |
| | APELA | Uncharacterized protein. (54 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (869 aa) |
| | ENSCAFP00000059123 | Uncharacterized protein. (106 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (760 aa) |
| | CDH13 | Cadherin 13. (713 aa) |
| | GLI1 | GLI family zinc finger 1. (1139 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (867 aa) |
| | CDC73 | Cell division cycle 73. (565 aa) |
| | NFIB | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (566 aa) |
| | CCL24 | C-C motif chemokine 24; Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Binds to CCR3 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (232 aa) |
| | ENSCAFP00000062699 | annotation not available (54 aa) |
| | NR4A1 | Nuclear receptor subfamily 4 group A member 1; Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation (By similarity). (606 aa) |
| | CD109 | CD109 molecule. (1577 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa) |
| | PTPRK | Protein tyrosine phosphatase receptor type K. (1555 aa) |
| | DLX6 | Distal-less homeobox 6. (248 aa) |
| | PTN | Pleiotrophin. (202 aa) |
| | ATP5IF1 | ATP synthase inhibitory factor subunit 1. (118 aa) |
| | ENSCAFP00000064776 | Uncharacterized protein. (525 aa) |
| | SAV1 | Salvador family WW domain containing protein 1. (384 aa) |
| | KRIT1 | KRIT1 ankyrin repeat containing. (749 aa) |
| | ENSCAFP00000066258 | SEA domain-containing protein. (257 aa) |
| | IQGAP3 | IQ motif containing GTPase activating protein 3. (1733 aa) |
