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| | BST1 | Bone marrow stromal cell antigen 1. (311 aa) |
| | CD27 | CD27 molecule. (229 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (732 aa) |
| | TNFSF4 | Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (183 aa) |
| | IGFBP2 | Insulin like growth factor binding protein 2. (186 aa) |
| | VSIR | V-set immunoregulatory receptor. (423 aa) |
| | LOC100687054 | Ig-like domain-containing protein. (212 aa) |
| | BCL6 | B-cell lymphoma 6 protein. (706 aa) |
| | ZP3 | Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. (441 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (784 aa) |
| | TFRC | Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity); Belongs to the [...] (918 aa) |
| | ICOS | Inducible T-cell costimulator; Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin- 2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40- mediated class switching o [...] (208 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1936 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule; Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those [...] (342 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | CD86 | CD86 molecule. (329 aa) |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2362 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (1086 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (179 aa) |
| | HLX | H2.0 like homeobox. (448 aa) |
| | MMP14 | Matrix metallopeptidase 14. (582 aa) |
| | CD160 | CD160 molecule. (277 aa) |
| | CD80 | CD80 molecule. (304 aa) |
| | HSPD1 | 60 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (573 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | DPP4 | Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (732 aa) |
| | CD81 | Tetraspanin. (233 aa) |
| | ZP4 | Zona pellucida glycoprotein 4. (562 aa) |
| | NOD2 | Uncharacterized protein. (1013 aa) |
| | EGR3 | Early growth response 3. (387 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (758 aa) |
| | IL7 | Interleukin 7. (155 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | IL36B | Interleukin-1. (164 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (327 aa) |
| | TOX | Thymocyte selection associated high mobility group box. (526 aa) |
| | SOX12 | Transcription factor SOX. (321 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (580 aa) |
| | SIRPA | Uncharacterized protein. (506 aa) |
| | SLC7A1 | Cationic amino acid transporter 1. (629 aa) |
| | PRKDC | DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act [...] (4067 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1133 aa) |
| | LAMP1 | Lysosomal associated membrane protein 1. (413 aa) |
| | GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | RIF1 | Replication timing regulatory factor 1. (2549 aa) |
| | RPS3 | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...] (243 aa) |
| | IL2RA | Interleukin-2 receptor subunit alpha; Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. (268 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (715 aa) |
| | PAXIP1 | PAX interacting protein 1. (1035 aa) |
| | AXL | AXL receptor tyrosine kinase. (879 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | B9D2 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | MYD88 | MYD88 innate immune signal transduction adaptor. (398 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (512 aa) |
| | LOC100687459 | AIG1-type G domain-containing protein. (341 aa) |
| | HMCES | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (357 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (155 aa) |
| | IL21 | Interleukin-21; Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity); Bel [...] (146 aa) |
| | FOXO3 | Forkhead box O3. (671 aa) |
| | EPHB6 | EPH receptor B6. (972 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | GLI3 | GLI family zinc finger 3. (1590 aa) |
| | IL4I1 | Interleukin 4 induced 1. (579 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | AKIRIN2 | Akirin 2. (203 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | KMT5C | Lysine methyltransferase 5C. (559 aa) |
| | E2R735_CANLF | Amino_oxidase domain-containing protein. (477 aa) |
| | EXOSC3 | Exosome component 3. (275 aa) |
| | PDCD1LG2 | Programmed cell death 1 ligand 2. (327 aa) |
| | CD274 | Programmed death ligand 1. (289 aa) |
| | NCK2 | Cytoplasmic protein. (380 aa) |
| | CCL19 | C-C motif chemokine. (115 aa) |
| | ANXA1 | Annexin. (345 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (340 aa) |
| | KITLG | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins. (335 aa) |
| | ZNF335 | Zinc finger protein 335. (1380 aa) |
| | GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (882 aa) |
| | CCDC88B | Non-specific serine/threonine protein kinase. (2130 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (579 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (859 aa) |
| | IGF2 | Insulin like growth factor 2. (304 aa) |
| | ADA | Adenosine deaminase. (402 aa) |
| | FCHO1 | FCH domain only 1. (938 aa) |
| | IL6ST | Uncharacterized protein. (954 aa) |
| | ENSCAFP00000062222 | Uncharacterized protein. (167 aa) |
| | AGER | Advanced glycosylation end product-specific receptor variant C. (396 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1301 aa) |
| | DOCK8 | Dedicator of cytokinesis 8; Belongs to the DOCK family. (2093 aa) |
| | EFNB1 | Ephrin B1. (377 aa) |
| | ENSCAFP00000060413 | Uncharacterized protein. (88 aa) |
| | MORN5 | MORN repeat containing 5. (278 aa) |
| | SH3KBP1 | SH3 domain containing kinase binding protein 1. (710 aa) |
| | PCID2 | PCI domain containing 2. (410 aa) |
| | MYB | MYB proto-oncogene, transcription factor. (799 aa) |
| | HV02_CANLF | Ig heavy chain V region MOO. (150 aa) |
| | INPP5D | Inositol polyphosphate-5-phosphatase D. (1501 aa) |
| | CD83 | CD83 molecule. (229 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (481 aa) |
| | ENSCAFP00000056204 | Uncharacterized protein. (59 aa) |
| | ENSCAFP00000055668 | Ig-like domain-containing protein. (142 aa) |
| | TNFSF13 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (252 aa) |
| | CD320 | CD320 molecule. (282 aa) |
| | SYK | Tyrosine-protein kinase. (699 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1385 aa) |
| | ENSCAFP00000054307 | Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (133 aa) |
| | ENSCAFP00000054037 | Ig-like domain-containing protein. (150 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (485 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | BLOC1S6 | Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (184 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (470 aa) |
| | LOC111092148 | Uncharacterized protein. (517 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] (228 aa) |
| | ENSCAFP00000052690 | Uncharacterized protein. (70 aa) |
| | CD28 | CD28 molecule. (246 aa) |
| | LOC477182 | Uncharacterized protein. (465 aa) |
| | ENSCAFP00000052529 | Uncharacterized protein. (59 aa) |
| | FAM49B | Family with sequence similarity 49 member B. (378 aa) |
| | TNFRSF13C | TNF receptor superfamily member 13C. (286 aa) |
| | F1PSQ5_CANLF | Uncharacterized protein. (228 aa) |
| | DLA-DOA | MHC class II antigen DO alpha; Belongs to the MHC class II family. (250 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (132 aa) |
| | DLA-DMA | MHC class II antigen DM alpha; Belongs to the MHC class II family. (265 aa) |
| | HLA-DQB1 | Major histocompatibility complex, class II, DQ beta 2. (303 aa) |
| | DLA-DQA1 | Ig-like domain-containing protein; Belongs to the MHC class II family. (344 aa) |
| | HLA-DQB2 | Major histocompatibility complex, class II, DQ beta 1. (205 aa) |
| | BTNL2 | Butyrophilin like 2. (505 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) |
| | IL23A | Interleukin 23 subunit alpha. (193 aa) |
| | MALT1 | MALT1 paracaspase. (758 aa) |
| | ENSCAFP00000052399 | Uncharacterized protein. (383 aa) |
| | HV01_CANLF | Ig heavy chain V region GOM. (474 aa) |
| | SHLD1 | Shieldin complex subunit 1. (259 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (593 aa) |
| | ENSCAFP00000050605 | Uncharacterized protein. (360 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (357 aa) |
| | BMI1 | RING-type domain-containing protein. (436 aa) |
| | TYK2 | Tyrosine-protein kinase. (1173 aa) |
| | ENSCAFP00000049448 | Ig-like domain-containing protein. (105 aa) |
| | ENSCAFP00000049310 | Uncharacterized protein. (176 aa) |
| | SOX13 | SRY-box 13. (618 aa) |
| | EXOSC6 | Exosome component 6. (395 aa) |
| | GAS6 | Growth arrest specific 6. (661 aa) |
| | ENSCAFP00000048133 | Ig-like domain-containing protein. (138 aa) |
| | NXPE3 | NFKB inhibitor zeta. (1002 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (130 aa) |
| | ENSCAFP00000047314 | Uncharacterized protein. (153 aa) |
| | ZAP70 | Tyrosine-protein kinase. (592 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (807 aa) |
| | STAT6 | Signal transducer and activator of transcription. (927 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (665 aa) |
| | CLEC1A | C-type lectin domain containing 7A. (283 aa) |
| | CD74 | CD74 molecule. (272 aa) |
| | DLA-DRA | Ig-like domain-containing protein; Belongs to the MHC class II family. (342 aa) |
| | ENSCAFP00000045270 | Ig-like domain-containing protein. (169 aa) |
| | ENSCAFP00000044582 | Ig-like domain-containing protein. (144 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (815 aa) |
| | ENSCAFP00000044033 | Ig-like domain-containing protein. (150 aa) |
| | J9PB46_CANLF | Uncharacterized protein. (59 aa) |
| | J9NT78_CANLF | Ig-like domain-containing protein. (397 aa) |
| | ZBTB1 | Zinc finger/BTB domain-containing protein 1 isoform 1. (712 aa) |
| | CD38 | CD38 molecule. (361 aa) |
| | KMT5B | Lysine methyltransferase 5B. (888 aa) |
| | TNFSF9 | TNF superfamily member 9; Belongs to the tumor necrosis factor family. (254 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | J9P859_CANLF | Galectin. (135 aa) |
| | THY1 | Ig-like domain-containing protein. (161 aa) |
| | TNFSF14 | Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. (240 aa) |
| | IL2RG | Cytokine receptor common subunit gamma; Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (By similarity). Belongs to the type I cytokine receptor family. Type 5 subfamily. (373 aa) |
| | HMGB1 | High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functio [...] (240 aa) |
| | LGALS1 | Galectin. (196 aa) |
| | J9NSS9_CANLF | Uncharacterized protein. (383 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (381 aa) |
| | J9NYE6_CANLF | Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (236 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (205 aa) |
| | LOC609123 | Uncharacterized protein. (451 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa) |
| | NSD2 | Nuclear receptor binding SET domain protein 2. (1344 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1825 aa) |
| | SHB | SH2 domain containing adaptor protein B. (508 aa) |
| | TNFSF13B | Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family. (370 aa) |
| | LOC609523 | Uncharacterized protein. (408 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | BLOC1S3 | Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (199 aa) |
| | VTCN1 | V-set domain containing T cell activation inhibitor 1. (282 aa) |
| | TLR9-2 | Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). (1032 aa) |
| | CBFB | Core-binding factor subunit beta. (82 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (233 aa) |
| | ABL1 | Tyrosine-protein kinase. (1150 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (591 aa) |
| | CD40LG | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (260 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (197 aa) |
| | F1PP29_CANLF | Uncharacterized protein. (499 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (755 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (329 aa) |
| | DHPS | Deoxyhypusine synthase. (369 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (685 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | TBX21 | T-box transcription factor 21. (535 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (196 aa) |
| | IL27RA | Interleukin 27 receptor subunit alpha. (780 aa) |
| | CD6 | CD6 molecule. (688 aa) |
| | CD5 | CD5 molecule. (511 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (936 aa) |
| | RASAL3 | RAS protein activator like 3. (1075 aa) |
| | FOXP3 | Forkhead box P3. (452 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | STAT5B | Signal transducer and activator of transcription. (787 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
