STRINGSTRING
DLL1 DLL1 DSPP DSPP DLX3 DLX3 DLG5 DLG5 BMP2 BMP2 J9P7A7_CANLF J9P7A7_CANLF OTP OTP SOX4 SOX4 TMEM231 TMEM231 ABL1 ABL1 NOTCH1 NOTCH1 B9D1 B9D1 BCCIP BCCIP LHX3 LHX3 VAX1 VAX1 MAP1B MAP1B ASCL1 ASCL1 JAG1 JAG1 WNT11 WNT11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (689 aa)
DSPPUncharacterized protein. (841 aa)
DLX3Distal-less homeobox 3. (319 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1940 aa)
BMP2Bone morphogenetic protein 2. (436 aa)
J9P7A7_CANLFHomeobox domain-containing protein. (305 aa)
OTPOrthopedia homeobox. (380 aa)
SOX4Transcription factor SOX. (344 aa)
TMEM231Transmembrane protein 231. (316 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
NOTCH1Notch receptor 1. (2565 aa)
B9D1B9 domain containing 1. (337 aa)
BCCIPBRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (315 aa)
LHX3LIM homeobox 3. (403 aa)
VAX1Ventral anterior homeobox 1. (334 aa)
MAP1BMicrotubule associated protein 1B. (2576 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (218 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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