STRINGSTRING
PRKAB2 PRKAB2 TAF9B TAF9B CDK13 CDK13 NRBF2 NRBF2 PIK3C2A PIK3C2A SNW1 SNW1 PARD6A PARD6A PHKA1 PHKA1 TGFBR1 TGFBR1 ENSCAFP00000040836 ENSCAFP00000040836 ATG101 ATG101 SETD5 SETD5 WDR41 WDR41 LOC484145 LOC484145 J9P8T9_CANLF J9P8T9_CANLF SESN2 SESN2 J9PAQ2_CANLF J9PAQ2_CANLF SOCS6 SOCS6 POLG2 POLG2 POLR3GL POLR3GL IGF1R IGF1R ENSCAFP00000043968 ENSCAFP00000043968 TAF2 TAF2 LEO1 LEO1 ENSCAFP00000045415 ENSCAFP00000045415 STRADA STRADA ENSCAFP00000045726 ENSCAFP00000045726 ENSCAFP00000046317 ENSCAFP00000046317 ACVR1 ACVR1 ENSCAFP00000046870 ENSCAFP00000046870 POLE4 POLE4 BECN1 BECN1 ENSCAFP00000047198 ENSCAFP00000047198 ENSCAFP00000047407 ENSCAFP00000047407 PHKB PHKB ENSCAFP00000047870 ENSCAFP00000047870 PRKAR1A PRKAR1A IKBKB IKBKB PIK3CA PIK3CA CRCP CRCP TERT TERT CDKN2D CDKN2D ENSCAFP00000049412 ENSCAFP00000049412 ENSCAFP00000049650 ENSCAFP00000049650 GTF2A2 GTF2A2 ENSCAFP00000049773 ENSCAFP00000049773 PRKAB1 PRKAB1 CDKN1A CDKN1A PRKAA1 PRKAA1 ENSCAFP00000051035 ENSCAFP00000051035 REV3L REV3L POLE2 POLE2 POLR2H POLR2H ENSCAFP00000051503 ENSCAFP00000051503 NEK10 NEK10 ENSCAFP00000051940 ENSCAFP00000051940 AMHR2 AMHR2 TCEA1 TCEA1 ENSCAFP00000053140 ENSCAFP00000053140 CCNT2 CCNT2 PHKA2 PHKA2 PIK3C2G PIK3C2G CCNI CCNI POLR2F POLR2F P3R3URF P3R3URF ENSCAFP00000055325 ENSCAFP00000055325 ACVR2A ACVR2A POLE POLE MYZAP MYZAP ENSCAFP00000056413 ENSCAFP00000056413 PFKP PFKP POLR3H POLR3H CDK5 CDK5 POLR2K POLR2K POLR3A POLR3A MYO6 MYO6 LAS1L LAS1L RB1 RB1 GTF2A2-2 GTF2A2-2 XRCC6 XRCC6 ALKAL1 ALKAL1 CCNQ CCNQ MNAT1 MNAT1 ERC1 ERC1 POLE3 POLE3 PRPS1 PRPS1 CDK14 CDK14 CDK2 CDK2 PAF1 PAF1 CKS1B CKS1B POLD3 POLD3 CDC73 CDC73 POLR2D POLR2D CCND3 CCND3 CCND1 CCND1 ENSCAFP00000062112 ENSCAFP00000062112 ERCC2 ERCC2 POLG POLG ENSCAFP00000062627 ENSCAFP00000062627 ENSCAFP00000062903 ENSCAFP00000062903 GTF2F1 GTF2F1 TAF5L TAF5L WDR47 WDR47 PRPS1L1 PRPS1L1 GTF2H3 GTF2H3 ZBTB7A ZBTB7A POLRMT POLRMT ENSCAFP00000066299 ENSCAFP00000066299 AK6 AK6 PFKFB1 PFKFB1 E2R8M3_CANLF E2R8M3_CANLF CCNB1 CCNB1 PRIM2 PRIM2 CCNH CCNH CCNL2 CCNL2 TADA3 TADA3 CCNI2 CCNI2 ATG13 ATG13 POLR2J POLR2J GTF2H5 GTF2H5 CNTD2 CNTD2 PRPSAP1 PRPSAP1 TAF7 TAF7 POLR1E POLR1E STK11 STK11 POLR2E POLR2E IKBKG IKBKG POLR3K POLR3K PIK3CD PIK3CD RPAP2 RPAP2 VAC14 VAC14 GTF2B GTF2B PRIM1 PRIM1 TBPL1 TBPL1 MAP3K5 MAP3K5 GTF2H4 GTF2H4 TAF11 TAF11 DAPK1 DAPK1 TAF8 TAF8 C11H9orf72 C11H9orf72 POLR3B POLR3B POLR1C POLR1C CDK6 CDK6 SUPT3H SUPT3H POLR2B POLR2B TWISTNB TWISTNB SOCS5 SOCS5 GTF2A1L GTF2A1L POLD2 POLD2 POLD1 POLD1 MAP3K7 MAP3K7 CCNY CCNY PARD3 PARD3 PIK3CG PIK3CG CCNA2 CCNA2 PIK3R3 PIK3R3 CD3EAP CD3EAP ERCC3 ERCC3 GTF2F2 GTF2F2 RECQL5 RECQL5 PRKAG2 PRKAG2 PRKAG3 PRKAG3 CDK3 CDK3 TAF3 TAF3 ACVR2B ACVR2B UVRAG UVRAG PCNA PCNA PRKAA2 PRKAA2 SOCS1 SOCS1 CDK5R1 CDK5R1 SMCR8 SMCR8 TAF4B TAF4B RPRD1A RPRD1A CCNK CCNK POLR3E POLR3E PIK3C3 PIK3C3 TAF7L TAF7L PIK3R5 PIK3R5 PIK3R6 PIK3R6 CCNJL CCNJL CCNG1 CCNG1 PYCARD PYCARD PHKG2 PHKG2 INSRR INSRR SOCS7 SOCS7 CCNB2 CCNB2 MAD2L2 MAD2L2 CDK12 CDK12 BECN2 BECN2 KAT2A KAT2A TAF6L TAF6L POLR2G POLR2G CCND2 CCND2 ATG14 ATG14 CDK5R2 CDK5R2 PIK3R4 PIK3R4 SOCS2 SOCS2 CCNA1 CCNA1 ULK1 ULK1 GTF2E2 GTF2E2 TAF10 TAF10 POLR2I POLR2I CCNO CCNO POLR1D POLR1D POLR1B POLR1B PIK3CB PIK3CB CCNE1 CCNE1 PIK3R1 PIK3R1 POLR1A POLR1A CTR9 CTR9 PRIMPOL PRIMPOL CDK7 CDK7 GTF2H2 GTF2H2 POLR3G POLR3G CCNJ CCNJ SLA2 SLA2 SOWAHB SOWAHB CCNG2 CCNG2 POLR2C POLR2C PRKAG1 PRKAG1 RPRD1B RPRD1B CCNL1 CCNL1 CCNT1 CCNT1 PFKM PFKM GTF2H1 GTF2H1 ACVR1C ACVR1C LOC608987 LOC608987 CCNE2 CCNE2 POLR3D POLR3D RTF1 RTF1 RPAP1 RPAP1 CHUK CHUK PIK3C2B PIK3C2B PHKG1 PHKG1 CISH CISH TAF5 TAF5 CAB39 CAB39 PFKL PFKL PRKAR1B PRKAR1B POLR3C POLR3C GTF2E1 GTF2E1 ZNFX1 ZNFX1 CLCF1 CLCF1 PRPS2 PRPS2 TAF12 TAF12 RPRD2 RPRD2 PRKAR2A PRKAR2A MAP3K6 MAP3K6 ZNRD1 ZNRD1 STRADB STRADB TAF4 TAF4 BCCIP BCCIP CDK1 CDK1 POLA1 POLA1 POLA2 POLA2 DNA2 DNA2 WDR61 WDR61 TAF6 TAF6 PRKCI PRKCI PIK3R2 PIK3R2 POLR2A POLR2A GTF2A1 GTF2A1 CDK9 CDK9 POLR2K-2 POLR2K-2 J9NXV6_CANLF J9NXV6_CANLF INSR INSR J9NYQ4_CANLF J9NYQ4_CANLF XRCC5 XRCC5 TAF1 TAF1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
TAF9BTATA-box binding protein associated factor 9b. (289 aa)
CDK13Cyclin dependent kinase 13. (1415 aa)
NRBF2Nuclear receptor binding factor 2. (288 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1693 aa)
SNW1SNW domain containing 1. (536 aa)
PARD6APar-6 family cell polarity regulator alpha. (514 aa)
PHKA1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1239 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ENSCAFP00000040836annotation not available (161 aa)
ATG101Autophagy related 101. (269 aa)
SETD5SET domain containing 5. (1482 aa)
WDR41WD repeat domain 41. (573 aa)
LOC484145RTR1-type domain-containing protein. (599 aa)
J9P8T9_CANLFCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (368 aa)
SESN2Sestrin 2. (485 aa)
J9PAQ2_CANLFCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (400 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
POLG2DNA polymerase gamma 2, accessory subunit. (554 aa)
POLR3GLDNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (254 aa)
IGF1RTyrosine-protein kinase receptor. (1403 aa)
ENSCAFP00000043968RPOL4c domain-containing protein. (108 aa)
TAF2TATA-box binding protein associated factor 2. (1258 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (708 aa)
ENSCAFP00000045415Uncharacterized protein. (282 aa)
STRADASTE20 related adaptor alpha. (431 aa)
ENSCAFP00000045726Uncharacterized protein; Belongs to the cyclin family. (391 aa)
ENSCAFP00000046317Uncharacterized protein. (78 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ENSCAFP00000046870CBS domain-containing protein. (112 aa)
POLE4CBFD_NFYB_HMF domain-containing protein. (275 aa)
BECN1Beclin 1. (471 aa)
ENSCAFP00000047198Uncharacterized protein. (99 aa)
ENSCAFP00000047407Uncharacterized protein. (112 aa)
PHKBPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1153 aa)
ENSCAFP00000047870WD_REPEATS_REGION domain-containing protein. (282 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (385 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CRCPCGRP receptor component. (232 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1253 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
ENSCAFP00000049412Uncharacterized protein. (98 aa)
ENSCAFP00000049650Uncharacterized protein. (104 aa)
GTF2A2General transcription factor IIA subunit 2. (175 aa)
ENSCAFP00000049773Uncharacterized protein. (64 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (275 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (357 aa)
PRKAA1Non-specific serine/threonine protein kinase. (573 aa)
ENSCAFP00000051035Uncharacterized protein. (340 aa)
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (3121 aa)
POLE2DNA polymerase epsilon 2, accessory subunit. (640 aa)
POLR2HRNA polymerase II subunit H. (122 aa)
ENSCAFP00000051503Uncharacterized protein. (190 aa)
NEK10NIMA related kinase 10. (1172 aa)
ENSCAFP00000051940Pribosyltran_N domain-containing protein. (204 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (565 aa)
TCEA1Transcription elongation factor A1. (484 aa)
ENSCAFP00000053140Uncharacterized protein. (59 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (745 aa)
PHKA2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1335 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1477 aa)
CCNICyclin I; Belongs to the cyclin family. (355 aa)
POLR2FRNA polymerase II subunit F. (167 aa)
P3R3URFPIK3R3 upstream reading frame. (95 aa)
ENSCAFP00000055325TFIIA_gamma_C domain-containing protein. (96 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (735 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2335 aa)
MYZAPUncharacterized protein. (765 aa)
ENSCAFP00000056413Pribosyltran_N domain-containing protein. (401 aa)
PFKPPhosphofructokinase, platelet. (870 aa)
POLR3HRNA polymerase III subunit H. (223 aa)
CDK5Cyclin dependent kinase 5. (390 aa)
POLR2KUncharacterized protein. (66 aa)
POLR3ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1402 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1285 aa)
LAS1LLAS1 like, ribosome biogenesis factor. (741 aa)
RB1RB transcriptional corepressor 1. (927 aa)
GTF2A2-2TFIIA_gamma_N domain-containing protein. (68 aa)
XRCC6X-ray repair cross complementing 6. (612 aa)
ALKAL1RB1 inducible coiled-coil 1. (1610 aa)
CCNQCyclin Q; Belongs to the cyclin family. (275 aa)
MNAT1MNAT1 component of CDK activating kinase. (358 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1120 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (187 aa)
PRPS1Phosphoribosyl pyrophosphate synthetase 1. (358 aa)
CDK14Cyclin dependent kinase 14; Belongs to the protein kinase superfamily. (469 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (577 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
POLD3DNA polymerase delta 3, accessory subunit. (541 aa)
CDC73Cell division cycle 73. (565 aa)
POLR2DRNA polymerase II subunit D. (182 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (380 aa)
CCND1G1/S-specific cyclin-D1; Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...] (331 aa)
ENSCAFP00000062112Uncharacterized protein. (367 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (764 aa)
POLGDNA polymerase gamma, catalytic subunit. (1346 aa)
ENSCAFP00000062627Uncharacterized protein; Belongs to the cyclin family. (404 aa)
ENSCAFP00000062903WD_REPEATS_REGION domain-containing protein. (204 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (605 aa)
TAF5LTATA-box binding protein associated factor 5 like. (653 aa)
WDR47WD repeat domain 47. (124 aa)
PRPS1L1Pribosyltran_N domain-containing protein. (268 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (714 aa)
POLRMTDNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1282 aa)
ENSCAFP00000066299Uncharacterized protein. (196 aa)
AK6Uncharacterized protein. (307 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (516 aa)
E2R8M3_CANLFUncharacterized protein. (157 aa)
CCNB1Uncharacterized protein; Belongs to the cyclin family. (425 aa)
PRIM2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (509 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
CCNL2Cyclin L2; Belongs to the cyclin family. (523 aa)
TADA3Transcriptional adaptor 3. (432 aa)
CCNI2Cyclin I family member 2; Belongs to the cyclin family. (292 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
POLR2JRNA polymerase II subunit J. (185 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
CNTD2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (198 aa)
PRPSAP1Phosphoribosyl pyrophosphate synthetase associated protein 1. (401 aa)
TAF7TATA-box binding protein associated factor 7. (349 aa)
POLR1ERNA polymerase I subunit E. (523 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (439 aa)
POLR2ERNA polymerase II subunit E. (253 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (419 aa)
POLR3KDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1083 aa)
RPAP2RTR1-type domain-containing protein. (617 aa)
VAC14VAC14 component of PIKFYVE complex. (783 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
PRIM1Uncharacterized protein. (185 aa)
TBPL1Uncharacterized protein. (186 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1366 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
TAF11TATA-box binding protein associated factor 11. (211 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
TAF8TATA-box binding protein associated factor 8. (310 aa)
C11H9orf72Chromosome 11 C9orf72 homolog. (481 aa)
POLR3BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa)
POLR1CRNA polymerase I and III subunit C. (346 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
SUPT3HSPT3 homolog, SAGA and STAGA complex component. (405 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1325 aa)
TWISTNBTWIST neighbor. (334 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
GTF2A1LUncharacterized protein. (476 aa)
POLD2DNA polymerase delta 2, accessory subunit. (519 aa)
POLD1DNA polymerase. (1107 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
CCNYCyclin Y; Belongs to the cyclin family. (332 aa)
PARD3Par-3 family cell polarity regulator. (1258 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1104 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
PIK3R3Uncharacterized protein. (461 aa)
CD3EAPCD3e molecule associated protein. (564 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (779 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (989 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (545 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (597 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (304 aa)
TAF3TATA-box binding protein associated factor 3. (932 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
UVRAGUV radiation resistance associated. (692 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
PRKAA2Non-specific serine/threonine protein kinase. (532 aa)
SOCS1Suppressor of cytokine signaling 1. (197 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
SMCR8SMCR8-C9orf72 complex subunit. (935 aa)
TAF4BTATA-box binding protein associated factor 4b. (867 aa)
RPRD1ARegulation of nuclear pre-mRNA domain containing 1A. (312 aa)
CCNKCyclin K; Belongs to the cyclin family. (379 aa)
POLR3ERNA polymerase III subunit E. (664 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (900 aa)
TAF7LTATA-box binding protein associated factor 7 like. (504 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (874 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (755 aa)
CCNJLUncharacterized protein; Belongs to the cyclin family. (391 aa)
CCNG1Cyclin G1; Belongs to the cyclin family. (295 aa)
PYCARDPYD and CARD domain containing. (195 aa)
PHKG2Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa)
INSRRTyrosine-protein kinase receptor. (1300 aa)
SOCS7Suppressor of cytokine signaling 7. (527 aa)
CCNB2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (397 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (196 aa)
CDK12Cyclin dependent kinase 12. (1490 aa)
BECN2Beclin 2. (389 aa)
KAT2ALysine acetyltransferase 2A. (903 aa)
TAF6LTATA-box binding protein associated factor 6 like. (625 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
CCND2Cyclin D2; Belongs to the cyclin family. (328 aa)
ATG14Autophagy related 14. (510 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (370 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
SOCS2Suppressor of cytokine signaling 2. (299 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1004 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (307 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
CCNOCyclin O; Belongs to the cyclin family. (352 aa)
POLR1DRNA polymerase I and III subunit D. (273 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1135 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (373 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
POLR1ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1717 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
PRIMPOLPrimase and DNA directed polymerase. (581 aa)
CDK7Cyclin dependent kinase 7. (346 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
POLR3GDNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa)
CCNJCyclin J; Belongs to the cyclin family. (383 aa)
SLA2Src like adaptor 2. (276 aa)
SOWAHBSosondowah ankyrin repeat domain family member B. (739 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (343 aa)
POLR2CRNA polymerase II subunit C. (280 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa)
RPRD1BRegulation of nuclear pre-mRNA domain containing 1B. (326 aa)
CCNL1Cyclin L1; Belongs to the cyclin family. (640 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (725 aa)
PFKMATP-dependent 6-phosphofructokinase, muscle type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (853 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (467 aa)
LOC608987Uncharacterized protein; Belongs to the cyclin family. (390 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (399 aa)
POLR3DRNA polymerase III subunit D. (398 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (714 aa)
RPAP1RNA polymerase II associated protein 1. (1394 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
PHKG1Phosphorylase kinase catalytic subunit gamma 1. (530 aa)
CISHCytokine inducible SH2 containing protein. (257 aa)
TAF5TATA-box binding protein associated factor 5. (801 aa)
CAB39Calcium binding protein 39. (341 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (443 aa)
POLR3CRNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa)
GTF2E1General transcription factor IIE subunit 1. (438 aa)
ZNFX1Zinc finger NFX1-type containing 1. (1918 aa)
CLCF1Cardiotrophin like cytokine factor 1. (261 aa)
PRPS2Phosphoribosyl pyrophosphate synthetase 2. (318 aa)
TAF12TFIID_20kDa domain-containing protein. (161 aa)
RPRD2Regulation of nuclear pre-mRNA domain containing 2. (1462 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (399 aa)
MAP3K6Mitogen-activated protein kinase kinase kinase 6. (1300 aa)
ZNRD1Zinc ribbon domain containing 1. (208 aa)
STRADBSTE20 related adaptor beta. (414 aa)
TAF4TATA-box binding protein associated factor 4. (848 aa)
BCCIPBRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (315 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
POLA1DNA polymerase. (1467 aa)
POLA2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (700 aa)
DNA2DNA replication helicase/nuclease 2. (1017 aa)
WDR61WD repeat domain 61. (305 aa)
TAF6TATA-box binding protein associated factor 6. (678 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa)
PIK3R2Uncharacterized protein. (726 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1789 aa)
GTF2A1General transcription factor IIA subunit 1. (392 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (489 aa)
POLR2K-2RNA polymerase II subunit K. (58 aa)
J9NXV6_CANLFTFIID_20kDa domain-containing protein. (209 aa)
INSRTyrosine-protein kinase receptor. (1406 aa)
J9NYQ4_CANLFUncharacterized protein. (206 aa)
XRCC5X-ray repair cross complementing 5. (829 aa)
TAF1Transcription initiation factor TFIID subunit. (1989 aa)
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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