14 items (Canis lupus familiaris) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	NOP10	NOP10 ribonucleoprotein. (64 aa)
	TERT	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1253 aa)
	TEP1	Telomerase associated protein 1. (2632 aa)
	DKC1	Dyskerin pseudouridine synthase 1. (683 aa)
	GAR1	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (210 aa)
	DHX36	DEAH-box helicase 36. (1122 aa)
	PINX1	PIN2 (TERF1) interacting telomerase inhibitor 1. (423 aa)
	SMG6	SMG6 nonsense mediated mRNA decay factor. (1412 aa)
	HNRNPU	Heterogeneous nuclear ribonucleoprotein U. (805 aa)
	SMG7	SMG7 nonsense mediated mRNA decay factor. (1179 aa)
	SMG5	SMG5 nonsense mediated mRNA decay factor. (1046 aa)
	NHP2	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (228 aa)
	ENSCAFP00000050766	G-patch domain-containing protein. (280 aa)
	EFNB3	Ephrin B3; Belongs to the ephrin family. (798 aa)

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DKC1	EFNB3	ENSCAFP00000029020	ENSCAFP00000053849	Dyskerin pseudouridine synthase 1.	Ephrin B3; Belongs to the ephrin family.	0.963
DKC1	GAR1	ENSCAFP00000029020	ENSCAFP00000016895	Dyskerin pseudouridine synthase 1.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.999
DKC1	NHP2	ENSCAFP00000029020	ENSCAFP00000063376	Dyskerin pseudouridine synthase 1.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.999
DKC1	NOP10	ENSCAFP00000029020	ENSCAFP00000038146	Dyskerin pseudouridine synthase 1.	NOP10 ribonucleoprotein.	0.999
DKC1	TERT	ENSCAFP00000029020	ENSCAFP00000048407	Dyskerin pseudouridine synthase 1.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.833
EFNB3	DKC1	ENSCAFP00000053849	ENSCAFP00000029020	Ephrin B3; Belongs to the ephrin family.	Dyskerin pseudouridine synthase 1.	0.963
EFNB3	GAR1	ENSCAFP00000053849	ENSCAFP00000016895	Ephrin B3; Belongs to the ephrin family.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.893
EFNB3	NHP2	ENSCAFP00000053849	ENSCAFP00000063376	Ephrin B3; Belongs to the ephrin family.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.929
EFNB3	NOP10	ENSCAFP00000053849	ENSCAFP00000038146	Ephrin B3; Belongs to the ephrin family.	NOP10 ribonucleoprotein.	0.887
EFNB3	TEP1	ENSCAFP00000053849	ENSCAFP00000048608	Ephrin B3; Belongs to the ephrin family.	Telomerase associated protein 1.	0.480
EFNB3	TERT	ENSCAFP00000053849	ENSCAFP00000048407	Ephrin B3; Belongs to the ephrin family.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.589
ENSCAFP00000050766	GAR1	ENSCAFP00000050766	ENSCAFP00000016895	G-patch domain-containing protein.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.449
ENSCAFP00000050766	NHP2	ENSCAFP00000050766	ENSCAFP00000063376	G-patch domain-containing protein.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.539
ENSCAFP00000050766	TERT	ENSCAFP00000050766	ENSCAFP00000048407	G-patch domain-containing protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.416
GAR1	DKC1	ENSCAFP00000016895	ENSCAFP00000029020	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	Dyskerin pseudouridine synthase 1.	0.999
GAR1	EFNB3	ENSCAFP00000016895	ENSCAFP00000053849	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	Ephrin B3; Belongs to the ephrin family.	0.893
GAR1	ENSCAFP00000050766	ENSCAFP00000016895	ENSCAFP00000050766	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	G-patch domain-containing protein.	0.449
GAR1	NHP2	ENSCAFP00000016895	ENSCAFP00000063376	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.998
GAR1	NOP10	ENSCAFP00000016895	ENSCAFP00000038146	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	NOP10 ribonucleoprotein.	0.998
GAR1	PINX1	ENSCAFP00000016895	ENSCAFP00000011936	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	PIN2 (TERF1) interacting telomerase inhibitor 1.	0.449