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| | J9NT78_CANLF | Ig-like domain-containing protein. (397 aa) |
| | ENSCAFP00000043591 | Uncharacterized protein. (176 aa) |
| | BTK | Tyrosine-protein kinase. (687 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (620 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (815 aa) |
| | TWSG1 | Twisted gastrulation BMP signaling modulator 1. (247 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4- diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5- tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4. The lipid phosphatase activity is critical for its tumor [...] (403 aa) |
| | CD74 | CD74 molecule. (272 aa) |
| | STAT6 | Signal transducer and activator of transcription. (927 aa) |
| | LYN | Tyrosine-protein kinase. (566 aa) |
| | DLG2 | Discs large MAGUK scaffold protein 2. (1012 aa) |
| | ENSCAFP00000047314 | Uncharacterized protein. (153 aa) |
| | RIPK3 | Protein kinase domain-containing protein. (423 aa) |
| | PRKAR1A | Protein kinase cAMP-dependent type I regulatory subunit alpha. (385 aa) |
| | MAPK3-2 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | LGALS9 | Galectin. (373 aa) |
| | ENSCAFP00000049310 | Uncharacterized protein. (176 aa) |
| | TYK2 | Tyrosine-protein kinase. (1173 aa) |
| | BMI1 | RING-type domain-containing protein. (436 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (357 aa) |
| | VSIG4 | V-set and immunoglobulin domain containing 4. (403 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (593 aa) |
| | SCRIB | Scribble planar cell polarity protein. (1568 aa) |
| | DLG5 | Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1940 aa) |
| | AHR | Aryl hydrocarbon receptor. (853 aa) |
| | CD28 | CD28 molecule. (246 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] (228 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (470 aa) |
| | RASSF5 | Ras association domain family member 5. (434 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1003 aa) |
| | TNFRSF1B | TNF receptor superfamily member 1B. (482 aa) |
| | PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity). (124 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1385 aa) |
| | SYK | Tyrosine-protein kinase. (699 aa) |
| | CD320 | CD320 molecule. (282 aa) |
| | MAPK8IP1 | Mitogen-activated protein kinase 8 interacting protein 1. (696 aa) |
| | IL34 | Interleukin 34. (261 aa) |
| | ARG2 | Arginase. (384 aa) |
| | INPP5D | Inositol polyphosphate-5-phosphatase D. (1501 aa) |
| | CSF1 | Colony stimulating factor 1. (587 aa) |
| | ENSCAFP00000060413 | Uncharacterized protein. (88 aa) |
| | EFNB1 | Ephrin B1. (377 aa) |
| | LOC484343 | Uncharacterized protein. (750 aa) |
| | AGER | Advanced glycosylation end product-specific receptor variant C. (396 aa) |
| | ENSCAFP00000062504 | Galectin. (257 aa) |
| | IDO1 | Indoleamine 2,3-dioxygenase 1. (421 aa) |
| | IL6ST | Uncharacterized protein. (954 aa) |
| | ADA | Adenosine deaminase. (402 aa) |
| | IGF2 | Insulin like growth factor 2. (304 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa) |
| | CNN2 | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (427 aa) |
| | F1PXS7_CANLF | Protein kinase domain-containing protein. (232 aa) |
| | CD40LG | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (260 aa) |
| | TNFRSF13B | TNF receptor superfamily member 13B. (289 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (329 aa) |
| | DHPS | Deoxyhypusine synthase. (369 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (685 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (283 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | IL27RA | Interleukin 27 receptor subunit alpha. (780 aa) |
| | MAD1L1 | Mitotic arrest deficient 1 like 1. (740 aa) |
| | CD6 | CD6 molecule. (688 aa) |
| | PKN1 | Protein kinase N1. (1145 aa) |
| | IKZF3 | IKAROS family zinc finger 3. (509 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | RASAL3 | RAS protein activator like 3. (1075 aa) |
| | FOXP3 | Forkhead box P3. (452 aa) |
| | STAT5B | Signal transducer and activator of transcription. (787 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | BST1 | Bone marrow stromal cell antigen 1. (311 aa) |
| | PLA2G2F | Phospholipase A(2). (210 aa) |
| | PLA2G2D | Phospholipase A(2). (146 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (732 aa) |
| | LGALS3 | Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage [...] (299 aa) |
| | BMP4 | TGF_BETA_2 domain-containing protein. (409 aa) |
| | TNFSF18 | TNF superfamily member 18. (190 aa) |
| | TNFSF4 | Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (183 aa) |
| | IGFBP2 | Insulin like growth factor binding protein 2. (186 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1132 aa) |
| | VSIR | V-set immunoregulatory receptor. (423 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1375 aa) |
| | BCL6 | B-cell lymphoma 6 protein. (706 aa) |
| | ZP3 | Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. (441 aa) |
| | TFRC | Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity); Belongs to the [...] (918 aa) |
| | CTLA4 | Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. (223 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule; Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those [...] (342 aa) |
| | CD86 | CD86 molecule. (329 aa) |
| | CRTAM | Cytotoxic and regulatory T cell molecule. (393 aa) |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2362 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (1086 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (179 aa) |
| | PRKAR1B | Protein kinase cAMP-dependent type I regulatory subunit beta. (443 aa) |
| | CD80 | CD80 molecule. (304 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | LOC484865 | C-type lectin domain-containing protein. (224 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (859 aa) |
| | CCDC88B | Non-specific serine/threonine protein kinase. (2130 aa) |
| | GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (882 aa) |
| | NDFIP1 | Nedd4 family interacting protein 1. (225 aa) |
| | ZNF335 | Zinc finger protein 335. (1380 aa) |
| | KITLG | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins. (335 aa) |
| | NMB | Neuromedin B. (126 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (346 aa) |
| | IL27 | Interleukin 27. (232 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa) |
| | LRRC1 | Leucine rich repeat containing 1. (511 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (205 aa) |
| | J9NYK3_CANLF | Uncharacterized protein. (106 aa) |
| | IL23A | Interleukin 23 subunit alpha. (193 aa) |
| | J9NZ35_CANLF | Calponin-homology (CH) domain-containing protein. (380 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (381 aa) |
| | TMEM131L | Transmembrane 131 like. (1557 aa) |
| | HMGB1 | High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functio [...] (240 aa) |
| | TNFSF9 | TNF superfamily member 9; Belongs to the tumor necrosis factor family. (254 aa) |
| | TNFRSF9 | TNF receptor superfamily member 9. (255 aa) |
| | GLMN | Glomulin, FKBP associated protein. (599 aa) |
| | TLR9-2 | Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). (1032 aa) |
| | ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. (874 aa) |
| | BTNL2 | Butyrophilin like 2. (505 aa) |
| | HLA-DQB1 | Major histocompatibility complex, class II, DQ beta 2. (303 aa) |
| | IRF1 | Interferon regulatory factor 1. (437 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (132 aa) |
| | TNFRSF13C | TNF receptor superfamily member 13C. (286 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | CSF2RB | Colony stimulating factor 2 receptor beta common subunit. (902 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (340 aa) |
| | ANXA1 | Annexin. (345 aa) |
| | CCL19 | C-C motif chemokine. (115 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (975 aa) |
| | TNFRSF21 | Uncharacterized protein. (623 aa) |
| | NCK2 | Cytoplasmic protein. (380 aa) |
| | CD274 | Programmed death ligand 1. (289 aa) |
| | PDCD1LG2 | Programmed cell death 1 ligand 2. (327 aa) |
| | E2R735_CANLF | Amino_oxidase domain-containing protein. (477 aa) |
| | GPNMB | Glycoprotein nmb. (554 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | IL4I1 | Interleukin 4 induced 1. (579 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | IL21 | Interleukin-21; Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity); Bel [...] (146 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (155 aa) |
| | MYD88 | MYD88 innate immune signal transduction adaptor. (398 aa) |
| | FOXJ1 | Forkhead box J1. (422 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (715 aa) |
| | IL2RA | Interleukin-2 receptor subunit alpha; Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. (268 aa) |
| | LRRC32 | Leucine rich repeat containing 32. (661 aa) |
| | RPS3 | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...] (243 aa) |
| | MZB1 | Marginal zone B and B1 cell specific protein. (199 aa) |
| | GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | PRNP | Major prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...] (255 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1353 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1133 aa) |
| | SLC7A1 | Cationic amino acid transporter 1. (629 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (580 aa) |
| | TMEM147 | Transmembrane protein 147. (224 aa) |
| | CD22 | CD22 molecule. (880 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (327 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | IL20RB | Interleukin 20 receptor subunit beta. (311 aa) |
| | HHEX | Hematopoietically expressed homeobox. (270 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (862 aa) |
| | SH3RF1 | SH3 domain containing ring finger 1. (882 aa) |
| | BLK | Tyrosine-protein kinase. (500 aa) |
| | GREM1 | Gremlin 1, DAN family BMP antagonist. (230 aa) |
| | IL7 | Interleukin 7. (155 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | MARCHF7 | Membrane associated ring-CH-type finger 7. (708 aa) |
| | CBLB | Cbl proto-oncogene B. (1004 aa) |
| | ZP4 | Zona pellucida glycoprotein 4. (562 aa) |
| | TSPAN32 | Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (301 aa) |
| | CD81 | Tetraspanin. (233 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | VTCN1 | V-set domain containing T cell activation inhibitor 1. (282 aa) |
| | CSF2 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. (144 aa) |
| | E2R2G4_CANLF | Uncharacterized protein. (652 aa) |
| | LGALS7 | Galectin. (194 aa) |
| | OCSTAMP | Osteoclast stimulatory transmembrane protein. (484 aa) |
| | NF1 | Neurofibromin 1. (2784 aa) |
| | TNFSF13B | Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family. (370 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1825 aa) |
| | CD38 | CD38 molecule. (361 aa) |
