10 items (Canis lupus familiaris) - STRING interaction network

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second shell of interactors

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Your Input:
	TLE1	TLE family member 1, transcriptional corepressor. (762 aa)
	CTNNB1	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] (744 aa)
	TCF7L1	Transcription factor 7 like 1. (588 aa)
	LDB1	LIM domain binding 1. (375 aa)
	BCL9	BCL9 transcription coactivator. (1426 aa)
	PYGO2	Pygopus family PHD finger 2. (405 aa)
	TCF7L2	Transcription factor 7 like 2. (565 aa)
	TCF7	Transcription factor 7. (484 aa)
	BCL9L	BCL9 like. (1481 aa)
	LEF1	Lymphoid enhancer binding factor 1. (481 aa)

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL9	BCL9L	ENSCAFP00000016276	ENSCAFP00000054160	BCL9 transcription coactivator.	BCL9 like.	0.592
BCL9	CTNNB1	ENSCAFP00000016276	ENSCAFP00000007783	BCL9 transcription coactivator.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.940
BCL9	LEF1	ENSCAFP00000016276	ENSCAFP00000056485	BCL9 transcription coactivator.	Lymphoid enhancer binding factor 1.	0.759
BCL9	PYGO2	ENSCAFP00000016276	ENSCAFP00000025271	BCL9 transcription coactivator.	Pygopus family PHD finger 2.	0.538
BCL9	TCF7	ENSCAFP00000016276	ENSCAFP00000043629	BCL9 transcription coactivator.	Transcription factor 7.	0.683
BCL9	TCF7L1	ENSCAFP00000016276	ENSCAFP00000011603	BCL9 transcription coactivator.	Transcription factor 7 like 1.	0.792
BCL9	TCF7L2	ENSCAFP00000016276	ENSCAFP00000039879	BCL9 transcription coactivator.	Transcription factor 7 like 2.	0.866
BCL9	TLE1	ENSCAFP00000016276	ENSCAFP00000002118	BCL9 transcription coactivator.	TLE family member 1, transcriptional corepressor.	0.528
BCL9L	BCL9	ENSCAFP00000054160	ENSCAFP00000016276	BCL9 like.	BCL9 transcription coactivator.	0.592
BCL9L	CTNNB1	ENSCAFP00000054160	ENSCAFP00000007783	BCL9 like.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.524
BCL9L	LEF1	ENSCAFP00000054160	ENSCAFP00000056485	BCL9 like.	Lymphoid enhancer binding factor 1.	0.586
BCL9L	PYGO2	ENSCAFP00000054160	ENSCAFP00000025271	BCL9 like.	Pygopus family PHD finger 2.	0.639
BCL9L	TCF7	ENSCAFP00000054160	ENSCAFP00000043629	BCL9 like.	Transcription factor 7.	0.541
BCL9L	TCF7L1	ENSCAFP00000054160	ENSCAFP00000011603	BCL9 like.	Transcription factor 7 like 1.	0.528
BCL9L	TCF7L2	ENSCAFP00000054160	ENSCAFP00000039879	BCL9 like.	Transcription factor 7 like 2.	0.532
BCL9L	TLE1	ENSCAFP00000054160	ENSCAFP00000002118	BCL9 like.	TLE family member 1, transcriptional corepressor.	0.510
CTNNB1	BCL9	ENSCAFP00000007783	ENSCAFP00000016276	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	BCL9 transcription coactivator.	0.940
CTNNB1	BCL9L	ENSCAFP00000007783	ENSCAFP00000054160	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	BCL9 like.	0.524
CTNNB1	LEF1	ENSCAFP00000007783	ENSCAFP00000056485	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	Lymphoid enhancer binding factor 1.	0.999
CTNNB1	TCF7	ENSCAFP00000007783	ENSCAFP00000043629	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	Transcription factor 7.	0.989