17 items (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC474964	Uncharacterized protein. (102 aa)
	RPLP2	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (115 aa)
	RRH	Retinal pigment epithelium-derived rhodopsin homolog; Belongs to the G-protein coupled receptor 1 family. (347 aa)
	SMG7	SMG7 nonsense mediated mRNA decay factor. (1179 aa)
	SMG6	SMG6 nonsense mediated mRNA decay factor. (1412 aa)
	ACD	ACD shelterin complex subunit and telomerase recruitment factor. (455 aa)
	NHP2	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (228 aa)
	SMG5	SMG5 nonsense mediated mRNA decay factor. (1046 aa)
	ENSCAFP00000062429	Uncharacterized protein. (152 aa)
	HNRNPC	RRM domain-containing protein. (315 aa)
	TEP1	Telomerase associated protein 1. (2632 aa)
	TERT	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1253 aa)
	ENSCAFP00000044834	Uncharacterized protein. (103 aa)
	J9P6M3_CANLF	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (115 aa)
	NVL	Nuclear VCP like. (855 aa)
	NOP10	NOP10 ribonucleoprotein. (64 aa)
	HNRNPC-2	RRM domain-containing protein. (294 aa)

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACD	NHP2	ENSCAFP00000032488	ENSCAFP00000063376	ACD shelterin complex subunit and telomerase recruitment factor.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.561
ACD	NOP10	ENSCAFP00000032488	ENSCAFP00000038146	ACD shelterin complex subunit and telomerase recruitment factor.	NOP10 ribonucleoprotein.	0.561
ACD	TERT	ENSCAFP00000032488	ENSCAFP00000048407	ACD shelterin complex subunit and telomerase recruitment factor.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.837
HNRNPC-2	LOC474964	ENSCAFP00000036717	ENSCAFP00000038452	RRM domain-containing protein.	Uncharacterized protein.	0.900
J9P6M3_CANLF	NHP2	ENSCAFP00000041306	ENSCAFP00000063376	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.687
LOC474964	HNRNPC-2	ENSCAFP00000038452	ENSCAFP00000036717	Uncharacterized protein.	RRM domain-containing protein.	0.900
NHP2	ACD	ENSCAFP00000063376	ENSCAFP00000032488	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	ACD shelterin complex subunit and telomerase recruitment factor.	0.561
NHP2	J9P6M3_CANLF	ENSCAFP00000063376	ENSCAFP00000041306	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family.	0.687
NHP2	NOP10	ENSCAFP00000063376	ENSCAFP00000038146	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	NOP10 ribonucleoprotein.	0.999
NHP2	RPLP2	ENSCAFP00000063376	ENSCAFP00000014004	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family.	0.694
NHP2	TERT	ENSCAFP00000063376	ENSCAFP00000048407	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.889
NOP10	ACD	ENSCAFP00000038146	ENSCAFP00000032488	NOP10 ribonucleoprotein.	ACD shelterin complex subunit and telomerase recruitment factor.	0.561
NOP10	NHP2	ENSCAFP00000038146	ENSCAFP00000063376	NOP10 ribonucleoprotein.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.999
NOP10	TERT	ENSCAFP00000038146	ENSCAFP00000048407	NOP10 ribonucleoprotein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.873
RPLP2	NHP2	ENSCAFP00000014004	ENSCAFP00000063376	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.694
SMG5	SMG6	ENSCAFP00000063012	ENSCAFP00000028416	SMG5 nonsense mediated mRNA decay factor.	SMG6 nonsense mediated mRNA decay factor.	0.933
SMG5	SMG7	ENSCAFP00000063012	ENSCAFP00000019592	SMG5 nonsense mediated mRNA decay factor.	SMG7 nonsense mediated mRNA decay factor.	0.959
SMG5	TERT	ENSCAFP00000063012	ENSCAFP00000048407	SMG5 nonsense mediated mRNA decay factor.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.689
SMG6	SMG5	ENSCAFP00000028416	ENSCAFP00000063012	SMG6 nonsense mediated mRNA decay factor.	SMG5 nonsense mediated mRNA decay factor.	0.933
SMG6	SMG7	ENSCAFP00000028416	ENSCAFP00000019592	SMG6 nonsense mediated mRNA decay factor.	SMG7 nonsense mediated mRNA decay factor.	0.900