(11 nodes) Seh1-associated complex network (Canis lupus familiaris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CASTOR2	Uncharacterized protein. (298 aa)
	MIOS	Meiosis regulator for oocyte development. (875 aa)
	METTL25	Methyltransferase like 25. (606 aa)
	NPRL2	NPR2 like, GATOR1 complex subunit. (380 aa)
	CASTOR1	Cytosolic arginine sensor for mTORC1 subunit 1. (329 aa)
	WDR24	WD repeat domain 24. (735 aa)
	NPRL3	NPR3 like, GATOR1 complex subunit. (744 aa)
	DEPDC5	DEP domain containing 5. (1646 aa)
	SESN1	Sestrin 1. (658 aa)
	WDR59	WD repeat domain 59. (989 aa)
	ENSCAFP00000063173	Uncharacterized protein. (97 aa)

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASTOR1	CASTOR2	ENSCAFP00000018407	ENSCAFP00000018417	Cytosolic arginine sensor for mTORC1 subunit 1.	Uncharacterized protein.	0.954
CASTOR1	DEPDC5	ENSCAFP00000018407	ENSCAFP00000050074	Cytosolic arginine sensor for mTORC1 subunit 1.	DEP domain containing 5.	0.571
CASTOR1	MIOS	ENSCAFP00000018407	ENSCAFP00000003259	Cytosolic arginine sensor for mTORC1 subunit 1.	Meiosis regulator for oocyte development.	0.968
CASTOR1	NPRL2	ENSCAFP00000018407	ENSCAFP00000015575	Cytosolic arginine sensor for mTORC1 subunit 1.	NPR2 like, GATOR1 complex subunit.	0.578
CASTOR1	NPRL3	ENSCAFP00000018407	ENSCAFP00000049363	Cytosolic arginine sensor for mTORC1 subunit 1.	NPR3 like, GATOR1 complex subunit.	0.561
CASTOR1	SESN1	ENSCAFP00000018407	ENSCAFP00000053155	Cytosolic arginine sensor for mTORC1 subunit 1.	Sestrin 1.	0.674
CASTOR1	WDR24	ENSCAFP00000018407	ENSCAFP00000029025	Cytosolic arginine sensor for mTORC1 subunit 1.	WD repeat domain 24.	0.720
CASTOR1	WDR59	ENSCAFP00000018407	ENSCAFP00000057181	Cytosolic arginine sensor for mTORC1 subunit 1.	WD repeat domain 59.	0.944
CASTOR2	CASTOR1	ENSCAFP00000018417	ENSCAFP00000018407	Uncharacterized protein.	Cytosolic arginine sensor for mTORC1 subunit 1.	0.954
CASTOR2	DEPDC5	ENSCAFP00000018417	ENSCAFP00000050074	Uncharacterized protein.	DEP domain containing 5.	0.684
CASTOR2	MIOS	ENSCAFP00000018417	ENSCAFP00000003259	Uncharacterized protein.	Meiosis regulator for oocyte development.	0.769
CASTOR2	NPRL2	ENSCAFP00000018417	ENSCAFP00000015575	Uncharacterized protein.	NPR2 like, GATOR1 complex subunit.	0.545
CASTOR2	NPRL3	ENSCAFP00000018417	ENSCAFP00000049363	Uncharacterized protein.	NPR3 like, GATOR1 complex subunit.	0.557
CASTOR2	WDR24	ENSCAFP00000018417	ENSCAFP00000029025	Uncharacterized protein.	WD repeat domain 24.	0.737
CASTOR2	WDR59	ENSCAFP00000018417	ENSCAFP00000057181	Uncharacterized protein.	WD repeat domain 59.	0.652
DEPDC5	CASTOR1	ENSCAFP00000050074	ENSCAFP00000018407	DEP domain containing 5.	Cytosolic arginine sensor for mTORC1 subunit 1.	0.571
DEPDC5	CASTOR2	ENSCAFP00000050074	ENSCAFP00000018417	DEP domain containing 5.	Uncharacterized protein.	0.684
DEPDC5	ENSCAFP00000063173	ENSCAFP00000050074	ENSCAFP00000063173	DEP domain containing 5.	Uncharacterized protein.	0.939
DEPDC5	MIOS	ENSCAFP00000050074	ENSCAFP00000003259	DEP domain containing 5.	Meiosis regulator for oocyte development.	0.998
DEPDC5	NPRL2	ENSCAFP00000050074	ENSCAFP00000015575	DEP domain containing 5.	NPR2 like, GATOR1 complex subunit.	0.999