(6 nodes) Troponin network (Canis lupus familiaris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TNNI2	Troponin I2, fast skeletal type. (182 aa)
	TNNI3	Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (211 aa)
	TNNI1	Troponin I1, slow skeletal type. (270 aa)
	TNNT2	Troponin T2, cardiac type. (296 aa)
	TNNT1	Troponin T1, slow skeletal type. (328 aa)
	TNNT3	Troponin T3, fast skeletal type. (340 aa)

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TNNI1	TNNI2	ENSCAFP00000015880	ENSCAFP00000014808	Troponin I1, slow skeletal type.	Troponin I2, fast skeletal type.	0.597
TNNI1	TNNI3	ENSCAFP00000015880	ENSCAFP00000003805	Troponin I1, slow skeletal type.	Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.526
TNNI1	TNNT1	ENSCAFP00000015880	ENSCAFP00000055435	Troponin I1, slow skeletal type.	Troponin T1, slow skeletal type.	0.967
TNNI1	TNNT2	ENSCAFP00000015880	ENSCAFP00000041330	Troponin I1, slow skeletal type.	Troponin T2, cardiac type.	0.963
TNNI1	TNNT3	ENSCAFP00000015880	ENSCAFP00000056461	Troponin I1, slow skeletal type.	Troponin T3, fast skeletal type.	0.943
TNNI2	TNNI1	ENSCAFP00000014808	ENSCAFP00000015880	Troponin I2, fast skeletal type.	Troponin I1, slow skeletal type.	0.597
TNNI2	TNNI3	ENSCAFP00000014808	ENSCAFP00000003805	Troponin I2, fast skeletal type.	Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.577
TNNI2	TNNT1	ENSCAFP00000014808	ENSCAFP00000055435	Troponin I2, fast skeletal type.	Troponin T1, slow skeletal type.	0.973
TNNI2	TNNT2	ENSCAFP00000014808	ENSCAFP00000041330	Troponin I2, fast skeletal type.	Troponin T2, cardiac type.	0.947
TNNI2	TNNT3	ENSCAFP00000014808	ENSCAFP00000056461	Troponin I2, fast skeletal type.	Troponin T3, fast skeletal type.	0.976
TNNI3	TNNI1	ENSCAFP00000003805	ENSCAFP00000015880	Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	Troponin I1, slow skeletal type.	0.526
TNNI3	TNNI2	ENSCAFP00000003805	ENSCAFP00000014808	Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	Troponin I2, fast skeletal type.	0.577
TNNI3	TNNT1	ENSCAFP00000003805	ENSCAFP00000055435	Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	Troponin T1, slow skeletal type.	0.913
TNNI3	TNNT2	ENSCAFP00000003805	ENSCAFP00000041330	Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	Troponin T2, cardiac type.	0.969
TNNI3	TNNT3	ENSCAFP00000003805	ENSCAFP00000056461	Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	Troponin T3, fast skeletal type.	0.892
TNNT1	TNNI1	ENSCAFP00000055435	ENSCAFP00000015880	Troponin T1, slow skeletal type.	Troponin I1, slow skeletal type.	0.967
TNNT1	TNNI2	ENSCAFP00000055435	ENSCAFP00000014808	Troponin T1, slow skeletal type.	Troponin I2, fast skeletal type.	0.973
TNNT1	TNNI3	ENSCAFP00000055435	ENSCAFP00000003805	Troponin T1, slow skeletal type.	Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.913
TNNT1	TNNT2	ENSCAFP00000055435	ENSCAFP00000041330	Troponin T1, slow skeletal type.	Troponin T2, cardiac type.	0.608
TNNT1	TNNT3	ENSCAFP00000055435	ENSCAFP00000056461	Troponin T1, slow skeletal type.	Troponin T3, fast skeletal type.	0.694