(18 nodes) Putative peptidoglycan binding domain network (Canis lupus familiaris)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	MMP3	Stromelysin-1; Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase (By similarity); Belongs to the peptidase M10A family. (478 aa)
	MMP19	Matrix metallopeptidase 19. (547 aa)
	MMP24	Matrix metallopeptidase 24. (616 aa)
	MMP15	Matrix metallopeptidase 15. (618 aa)
	MMP16	Matrix metallopeptidase 16. (607 aa)
	MMP2	Matrix metallopeptidase 2. (610 aa)
	MMP14	Matrix metallopeptidase 14. (582 aa)
	MMP13	Matrix metallopeptidase 13. (496 aa)
	MMP8	Matrix metallopeptidase 8. (476 aa)
	MMP27	Matrix metallopeptidase 27. (512 aa)
	MMP20	Matrix metallopeptidase 20. (483 aa)
	MMP28	Matrix metallopeptidase 28. (520 aa)
	MMP25	Matrix metallopeptidase 25. (560 aa)
	MMP7	Matrix metallopeptidase 7. (263 aa)
	MMP12	ZnMc domain-containing protein. (491 aa)
	MMP9	Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity). (732 aa)
	MMP1	Matrix metallopeptidase 1. (465 aa)
	MMP21	Matrix metallopeptidase 21. (658 aa)

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MMP1	MMP12	ENSCAFP00000038708	ENSCAFP00000031802	Matrix metallopeptidase 1.	ZnMc domain-containing protein.	0.443
MMP1	MMP13	ENSCAFP00000038708	ENSCAFP00000022174	Matrix metallopeptidase 1.	Matrix metallopeptidase 13.	0.698
MMP1	MMP2	ENSCAFP00000038708	ENSCAFP00000013872	Matrix metallopeptidase 1.	Matrix metallopeptidase 2.	0.946
MMP1	MMP3	ENSCAFP00000038708	ENSCAFP00000022195	Matrix metallopeptidase 1.	Stromelysin-1; Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase (By similarity); Belongs to the peptidase M10A family.	0.950
MMP1	MMP7	ENSCAFP00000038708	ENSCAFP00000030464	Matrix metallopeptidase 1.	Matrix metallopeptidase 7.	0.675
MMP1	MMP9	ENSCAFP00000038708	ENSCAFP00000035167	Matrix metallopeptidase 1.	Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity).	0.952
MMP12	MMP1	ENSCAFP00000031802	ENSCAFP00000038708	ZnMc domain-containing protein.	Matrix metallopeptidase 1.	0.443
MMP12	MMP9	ENSCAFP00000031802	ENSCAFP00000035167	ZnMc domain-containing protein.	Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity).	0.424
MMP13	MMP1	ENSCAFP00000022174	ENSCAFP00000038708	Matrix metallopeptidase 13.	Matrix metallopeptidase 1.	0.698
MMP13	MMP14	ENSCAFP00000022174	ENSCAFP00000016472	Matrix metallopeptidase 13.	Matrix metallopeptidase 14.	0.815
MMP13	MMP16	ENSCAFP00000022174	ENSCAFP00000013128	Matrix metallopeptidase 13.	Matrix metallopeptidase 16.	0.796
MMP13	MMP2	ENSCAFP00000022174	ENSCAFP00000013872	Matrix metallopeptidase 13.	Matrix metallopeptidase 2.	0.683
MMP13	MMP3	ENSCAFP00000022174	ENSCAFP00000022195	Matrix metallopeptidase 13.	Stromelysin-1; Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase (By similarity); Belongs to the peptidase M10A family.	0.703
MMP13	MMP7	ENSCAFP00000022174	ENSCAFP00000030464	Matrix metallopeptidase 13.	Matrix metallopeptidase 7.	0.625
MMP13	MMP9	ENSCAFP00000022174	ENSCAFP00000035167	Matrix metallopeptidase 13.	Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity).	0.700
MMP14	MMP13	ENSCAFP00000016472	ENSCAFP00000022174	Matrix metallopeptidase 14.	Matrix metallopeptidase 13.	0.815
MMP14	MMP15	ENSCAFP00000016472	ENSCAFP00000012558	Matrix metallopeptidase 14.	Matrix metallopeptidase 15.	0.548
MMP14	MMP16	ENSCAFP00000016472	ENSCAFP00000013128	Matrix metallopeptidase 14.	Matrix metallopeptidase 16.	0.567
MMP14	MMP2	ENSCAFP00000016472	ENSCAFP00000013872	Matrix metallopeptidase 14.	Matrix metallopeptidase 2.	0.711
MMP14	MMP24	ENSCAFP00000016472	ENSCAFP00000011799	Matrix metallopeptidase 14.	Matrix metallopeptidase 24.	0.521