Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASTE1 | ATR | ENSCAFP00000009160 | ENSCAFP00000011639 | Asteroid homolog 1. | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.488 |
| ASTE1 | DBF4 | ENSCAFP00000009160 | ENSCAFP00000002695 | Asteroid homolog 1. | RUN domain containing 3B. | 0.454 |
| ASTE1 | EXO1 | ENSCAFP00000009160 | ENSCAFP00000023179 | Asteroid homolog 1. | Exonuclease 1. | 0.409 |
| ASTE1 | MAD2L2 | ENSCAFP00000009160 | ENSCAFP00000024383 | Asteroid homolog 1. | Mitotic arrest deficient 2 like 2. | 0.419 |
| ASTE1 | MRE11 | ENSCAFP00000009160 | ENSCAFP00000006193 | Asteroid homolog 1. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.453 |
| ASTE1 | MUS81 | ENSCAFP00000009160 | ENSCAFP00000019472 | Asteroid homolog 1. | MUS81 structure-specific endonuclease subunit. | 0.493 |
| ASTE1 | PALB2 | ENSCAFP00000009160 | ENSCAFP00000037206 | Asteroid homolog 1. | Partner and localizer of BRCA2. | 0.401 |
| ASTE1 | PIAS4 | ENSCAFP00000009160 | ENSCAFP00000028253 | Asteroid homolog 1. | Protein inhibitor of activated STAT 4. | 0.414 |
| ASTE1 | RAD50 | ENSCAFP00000009160 | ENSCAFP00000040203 | Asteroid homolog 1. | RAD50 double strand break repair protein. | 0.459 |
| ASTE1 | RIF1 | ENSCAFP00000009160 | ENSCAFP00000008476 | Asteroid homolog 1. | Replication timing regulatory factor 1. | 0.722 |
| ASTE1 | SHLD2 | ENSCAFP00000009160 | ENSCAFP00000051714 | Asteroid homolog 1. | Shieldin complex subunit 2. | 0.439 |
| ASTE1 | STN1 | ENSCAFP00000009160 | ENSCAFP00000042623 | Asteroid homolog 1. | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. | 0.446 |
| ASTE1 | TEN1 | ENSCAFP00000009160 | ENSCAFP00000039495 | Asteroid homolog 1. | TEN1 subunit of CST complex. | 0.535 |
| ASTE1 | TICRR | ENSCAFP00000009160 | ENSCAFP00000066250 | Asteroid homolog 1. | TOPBP1 interacting checkpoint and replication regulator. | 0.453 |
| ASTE1 | TP53BP1 | ENSCAFP00000009160 | ENSCAFP00000018569 | Asteroid homolog 1. | Tumor protein p53 binding protein 1. | 0.604 |
| ATM | ATR | ENSCAFP00000035996 | ENSCAFP00000011639 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.998 |
| ATM | BARD1 | ENSCAFP00000035996 | ENSCAFP00000021054 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | BRCA1 associated RING domain 1. | 0.888 |
| ATM | BLM | ENSCAFP00000035996 | ENSCAFP00000018251 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | BLM RecQ like helicase. | 0.910 |
| ATM | BRCA1 | ENSCAFP00000035996 | ENSCAFP00000048759 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.996 |
| ATM | BRCA2 | ENSCAFP00000035996 | ENSCAFP00000009557 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | BRCA2 DNA repair associated. | 0.943 |
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